ChemicalBook >> CAS DataBase List >>N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE

CAS No.
54130-36-8
Chemical Name:
N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
Synonyms
PGF2ALPHA-NET;Prostaglandin F2α ethyl amide;Prostaglandin F2α ethyl amide;PROSTAGLANDIN F2ALPHA ETHYL AMIDE;N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE;Prosta-5,13-dien-1-amide, N-ethyl-9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)- (9CI);(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
CBNumber:
CB3245107
Molecular Formula:
C22H39NO4
Molecular Weight:
381.55
MDL Number:
MFCD03411992
MOL File:
54130-36-8.mol
Last updated:2023-06-08 09:03:09

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Properties

storage temp. Store at -20°C
solubility DMF: 33mg/ml; DMSO: 16 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 300 μg/ml

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16016 Prostaglandin F2α ethyl amide ≥98% 54130-36-8 1mg $54 2024-03-01 Buy
Cayman Chemical 16016 Prostaglandin F2α ethyl amide ≥98% 54130-36-8 5mg $231 2024-03-01 Buy
Cayman Chemical 16016 Prostaglandin F2α ethyl amide ≥98% 54130-36-8 10mg $410 2024-03-01 Buy
AK Scientific 1928AH N-Ethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide 54130-36-8 5mg $355 2021-12-16 Buy
Product number Packaging Price Buy
16016 1mg $54 Buy
16016 5mg $231 Buy
16016 10mg $410 Buy
1928AH 5mg $355 Buy

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Chemical Properties,Uses,Production

Description

Prostaglandin F ethyl amide (PGF-NEt) is an analog of PGF in which the C-1 carboxyl group has been modified to an N-ethyl amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that PG ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. PGF-NEt would be expected to show the typical intraocular effects of PGF free acid, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE PROSTAGLANDIN F2ALPHA ETHYL AMIDE PGF2ALPHA-NET Prostaglandin F2α ethyl amide (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethylhept-5-enamide Prosta-5,13-dien-1-amide, N-ethyl-9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)- (9CI) Prostaglandin F2α ethyl amide 54130-36-8