ChemicalBook >> CAS DataBase List >>Lurasidone hydrochloride
Lurasidone hydrochloride
- CAS No.
- 367514-88-3
- Chemical Name:
- Lurasidone hydrochloride
- Synonyms
- Lurasidonhydrochloride;Lurasidon hcl;(3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride;CS-864;lurasidone HCI;Latuda, SM 13496;urasidone HydrochL;Exodiene Lurasidone;Lurasidonhydrochlorid;Lurasidone Hydrochlorid
- CBNumber:
- CB32500192
- Molecular Formula:
- C28H37ClN4O2S
- Molecular Weight:
- 529.14
- MDL Number:
- MFCD18917095
- MOL File:
- 367514-88-3.mol
Last updated:2025-01-27 09:38:02
| Melting point | 198-205°C |
|---|---|
| Flash point | 9℃ |
| storage temp. | Refrigerator |
| solubility | DMSO : 10 mg/mL (18.90 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| color | White to off-white |
| InChIKey | PQXKDMSYBGKCJA-CVTJIBDQSA-N |
| SMILES | O=C1N(C(=O)[C@@]2([H])[C@]3([H])CC[C@@]([H])(C3)[C@@]12[H])C[C@@H]1CCCC[C@H]1CN1CCN(C2=NSC3=CC=CC=C23)CC1.Cl |&1:5,7,11,14,17,22,r| |
| FDA UNII | O0P4I5851I |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H301+H311+H331-H370 |
| Precautionary statements | P210-P260-P280-P301+P310-P311 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 1 |
Lurasidone hydrochloride price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L-030 | Lurasidone hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 367514-88-3 | 1mL | $196 | 2024-03-01 | Buy |
| TRC | L474920 | LurasidoneHydrochloride | 367514-88-3 | 5mg | $180 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 27700 | LurasidoneHCl | 367514-88-3 | 5mg | $590 | 2021-12-16 | Buy |
| ChemScene | CS-0866 | LurasidoneHydrochloride 99.87% | 367514-88-3 | 500mg | $600 | 2021-12-16 | Buy |
| ChemScene | CS-0866 | LurasidoneHydrochloride 99.87% | 367514-88-3 | 200mg | $288 | 2021-12-16 | Buy |
Lurasidone hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
An antipsychotic used for treatment of schizophrenia.
Uses
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively
Definition
ChEBI: A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia.
Biological Activity
Lurasidone is an atypical antipsychotic, used clinically for treatment of schizophrenia and bi-polar disorder. It has nanomolar activity as an antagonist at dopamine D2, serotonin 5-HT2A, 5-HT7, and α2C-adrenergic receptors and as an agonist at 5-HT1A receptors.
Synthesis of Lurasidone hydrochloride from (3aR,7aR)-4'-(1,2-Benzisothiazol-3-yl)octahydrospiro[2H-isoindole-2,1'-piperaziniuM] Methanesulfonate and (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione
Lurasidone hydrochloride Preparation Products And Raw materials
Global( 346)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Jianfeng Chemical Co., Ltd | +86-0531-88110457 +86-15562555968 | info@pharmachemm.com | China | 334 | 58 |
| Shandong Risen-Sun Pharmaceutical Co., Ltd | +86-15552509998 +86-15621883869 | liutf@jewim.com.cn | China | 251 | 58 |
| Jinan Million Pharmaceutical Co., Ltd | 0531-68659554 +8613031714605 | info@millionpharm.com | China | 294 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 283 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10983 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
Related articles
- Lurasidone Hydrochloride: Pharmacodynamics, Clinical Effectiveness and Adverse Effects
- Lurasidone hydrochloride is clinically beneficial in treating patients with schizophrenia and bipolar depression.
- Nov 8，2024
- The application of Lurasidone hydrochloride
- The lurasidone hydrochloride, with the CAS No: 367514-88-3, is also known as Lurasidonhydrochloride. This chemical’s molecular....
- Jan 10，2023
View Lastest Price from Lurasidone hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-27 | Lurasidone hydrochloride
367514-88-3
|
US $2.00 / kg | 1kg | 99% | 200KG/M | Jinan Million Pharmaceutical Co., Ltd | |
 |
2025-04-27 | Luracidon hydrochloride
367514-88-3
|
US $2.00 / kg | 1kg | 99% | 200KG | Jinan Million Pharmaceutical Co., Ltd | |
 |
2025-04-23 | Lurasidone hydrochloride
367514-88-3
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Lurasidone hydrochloride
367514-88-3
- US $2.00 / kg
- 99%
- Jinan Million Pharmaceutical Co., Ltd
-
- Luracidon hydrochloride
367514-88-3
- US $2.00 / kg
- 99%
- Jinan Million Pharmaceutical Co., Ltd
-
- Lurasidone hydrochloride
367514-88-3
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
367514-88-3(Lurasidone hydrochloride)Related Search:
Lurasidonhydrochlorid
(3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride
(1R,2S,3R,4S)-N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinylMethyl]-1-cyclohexylMethyl]-2,3-bicyclo[2.2.1]heptanedicarboxyiMide hydrochloride
Latuda, SM 13496
Lurasidone Hydrochlorid
(3aR,4S,7R,7aS)-2-[(1R,2R)-2-[4-(1,2-Benzisothiazol-3-yl)piperazin-1-ylMethyl]cyclohexylMethyl]hexahydro-1H-4,7-Methanoisoindole-1,3-dione hydrochloride
Lurasidone Hydrochloride API
4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, hydrochloride (1:1), (3aR,4S,7R,7aS)-
Lurasidone hydrochloride solution
Lurasidone Hydrochloride Tablets
Exodiene Lurasidone
Lurasidone HCl / Lurasidone Hydrochloride
(3aR,4R,7S,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)
CS-864
SM-13496 (Hydrochloride)
urasidone HydrochL
(1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione hydrochloride
(3aR,4S,7R,7aS)-2-[(1R,2R)-2-[4-(1,2-Benzisothiazol-3-yl)piperazin-1-
Lurasidone hydrochloride USP/EP/BP
Lurasidone hydrochloride salt
(3aR,4S,7R,7aS)-2-{(1R,2R)-2-[4-(1,2-Benzisothiazol-3-yl)piperazin-1-yl methyl] cyclohexylmethyl}hexahydro-4,7-methano-2H-isoindole-1,3-dione hydrochloride
Lurasidone HCl (SM-13496)
(3aR,4S,7R,7aS)-2-[(1R,2R)-2-[4-(1,2-Benzisothiazol-3-yl)pip...
urasidone hydrochloride
Lurasidone HydrochlorideQ: What is
Lurasidone Hydrochloride Q: What is the CAS Number of
Lurasidone Hydrochloride Q: What is the storage condition of
Lurasidone Hydrochloride Q: What are the applications of
Lurasidone Hydrochloride
Lurasidonhydrochloride
Lurasidon hcl
(3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride
lurasidone HCI
Lurasidone hydrochloride,SM13496,Inhibitor,5-hydroxytryptamine Receptor,Lurasidone,5-HT Receptor,Dopamine Receptor,inhibit,SM 13496,Serotonin Receptor
(R)-2-[[2-(4-aminophenyl ethyl] aminol-1-phenylethanol monohydrochloride
Luracidon hydrochloride
Lurasidone hydrochloride, 10 mM in DMSO
Lurasidone (hydrochloride) (CRM)
367514-88-3
C28H36N4O2SHCl
C28H37ClN4O2S
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals
367514-88-3
API