SR 59230A HCl
- CAS No.
- 1135278-41-9
- Chemical Name:
- SR 59230A HCl
- Synonyms
- SR-59230A hydrochloride,SR59230A hydrochloride
- CBNumber:
- CB33038511
- Molecular Formula:
- C21H27NO2.HCl
- Molecular Weight:
- 361.91
- MDL Number:
- MFCD06795851
- MOL File:
- 1135278-41-9.mol
SR 59230A HCl price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 21407 | SR 59230A (hydrochloride) ≥99% | 1135278-41-9 | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 21407 | SR 59230A (hydrochloride) ≥99% | 1135278-41-9 | 5mg | $116 | 2024-03-01 | Buy |
Cayman Chemical | 21407 | SR 59230A (hydrochloride) ≥99% | 1135278-41-9 | 10mg | $195 | 2024-03-01 | Buy |
Cayman Chemical | 21407 | SR 59230A (hydrochloride) ≥99% | 1135278-41-9 | 25mg | $442 | 2024-03-01 | Buy |
TRC | S684443 | SR59230AHydrochloride | 1135278-41-9 | 10mg | $145 | 2021-12-16 | Buy |
SR 59230A HCl Chemical Properties,Uses,Production
Description
SR 59230A (hydrochloride) is a β3-adrenergic receptor (β3-AR) antagonist (pA2s = 8.76, 7.31, and 6.63 in rat proximal colon, guinea pig atrium, and guinea pig trachea, respectively). It is less selective for β3-AR in cells transfected with the human β-AR subtypes (Kis = 16.4, 61.9, and 122 nM for β1-, β2-, and β3-AR, respectively). At low concentrations, SR 59230A blocks MDMA-induced hyperthermia, while at high concentrations it blocks hyperthermia but also increases heat loss through an α1-AR antagonistic mechanism. In adipocytes, it induces phosphorylation of p38 MAPK via the Gs pathway. It has also been used in studies of heart failure to elucidate the role of the β3-ARs.
Uses
SR 59230A Hydrochloride is a potent and selective β3 adrenergic receptor antagonist.
storage
Store at RT
SR 59230A HCl Preparation Products And Raw materials
Raw materials
Preparation Products
SR 59230A HCl Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3770 | 55 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |