ChemicalBook >> CAS DataBase List >>2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

CAS No.
5381-99-7
Chemical Name:
2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE
Synonyms
2-Chloro-4H-benzo[d][1,3,2]dioxaphosphinin-4-one;Salicyl Phosphorochloridite;2-CHLORO-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE;2-CHLORO-4H-1,2,3-BENZODIOXAPHOSPHORIN-4-ONE;SALICYLCHLOROPHOSPHITE;SalPCl;NSC 40209;VAN BOOM'S REAGENT;ChloroHbenzodioxaphosphorinone;Salicylchlorophosphite Van Boom's Reagent
CBNumber:
CB3312737
Molecular Formula:
C7H4ClO3P
Molecular Weight:
202.53
MDL Number:
MFCD00013353
MOL File:
5381-99-7.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Properties

Melting point 36-40 °C (lit.)
Boiling point 127-128 °C/11 mmHg (lit.)
Flash point >230 °F
storage temp. 2-8°C
solubility Soluble in acetonitrile, dichloromethane, tetrahydrofuron and dimethylformamide.
form solid
color White or Colorless to Orange to Green
BRN 1311951
Stability Water Sensitive
CAS DataBase Reference 5381-99-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C
Risk Statements  14-34-37
Safety Statements  26-36/37/39-43-45
RIDADR  UN 3261 8/PG 1
WGK Germany  3
3-10
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  29349990
NFPA 704
1
3 0

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 324124 2-Chloro-1,3,2-benzodioxaphosphorin-4-one 95% 5381-99-7 5g $127 2024-03-01 Buy
Sigma-Aldrich 324124 2-Chloro-1,3,2-benzodioxaphosphorin-4-one 95% 5381-99-7 25g $343 2024-03-01 Buy
TCI Chemical C1210 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one >95.0%(T) 5381-99-7 5g $59 2024-03-01 Buy
TCI Chemical C1210 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one >95.0%(T) 5381-99-7 25g $178 2024-03-01 Buy
Alfa Aesar B21086 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one, 97% 5381-99-7 5g $68.65 2024-03-01 Buy
Product number Packaging Price Buy
324124 5g $127 Buy
324124 25g $343 Buy
C1210 5g $59 Buy
C1210 25g $178 Buy
B21086 5g $68.65 Buy

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

2-Chloro-1,3,2-benzodioxaphosphorin-4-one is used as a reagent:

  • In the phosphorylation and phosphitylation of alcohols.
  • In the formation of H-phosphonates which are commonly utilized in the synthesis of nucleotides.
  • To synthesize nucleoside triphosphates by treating with acyl protected nucleoside.

Uses

Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs

Uses

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one is a reagent used in phosphorylation and phosphitylation of alcohols and in the formation of H-phosphonates. It is also reactive cyclic phosphitylating reagent involved in fast coupling rates and hydrolytic cleavage more readily compare to that of a acyclic analog.

69-72-7
5381-99-7
Synthesis of 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE from Salicylic acid

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Preparation Products And Raw materials

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Suppliers

Global( 118)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3002 58
Richest Group Ltd
18017061086 oled@richest-group.com CHINA 5600 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 13505 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58

View Lastest Price from 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one   pictures 2020-03-16 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one
5381-99-7
US $1.00-0.00 / KG 1KG 99% 20 tons Shaanxi Dideu Medichem Co. Ltd
VAN BOOM'S REAGENT 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE ChloroHbenzodioxaphosphorinone 2-Chloro-4H-1,2,3-benzodioxaphosphorin-4-one 90% 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE 97% NSC 40209 Salicylchlorophosphite Van Boom's Reagent 2-Chloro-4H-1,3,2-benzodioxaphosphinin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one, Salicyl chlorophosphite SalPCl 2-Chloro-1,3,2-benzodioxaphosphorin-4-one 95% 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one,97% 4H-1,3,2-Benzodioxaphosphorin-4-one,2-chloro- 2-chloro-1,3,2-benzodioxaphosphonic heterocyclohexane-4-one 2-chloro-1,3,2-benzodioxaphosphinin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphinin-4-one 95% 2-chloro-2,4-dihydro-1,3,2-benzodioxaphosphinin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one > 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one (90%) "2-Chloro-4H-1,2,3-benzodioxaphosphorin-4-one 90%" 5381-99-7 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE C7H4ClO3P 2-Chloro-4H-benzo[d][1,3,2]dioxaphosphinin-4-one Salicyl Phosphorochloridite 2-CHLORO-4H-1,2,3-BENZODIOXAPHOSPHORIN-4-ONE 2-CHLORO-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE SALICYLCHLOROPHOSPHITE 5381-99-7 C7H4ClO3P Phosphorylating Agents Phosphorylation DNA / RNA Synthesis Catalysis and Inorganic Chemistry Phosphorus Compounds Phosphorus Precursors Phospholipids - 13C & 2H Biochemistry Nucleosides, Nucleotides & Related Reagents Phosphorylating and Phosphorothioating Agents Phosphorylation Protecting Agents, Phosphorylating Agents & Condensing Agents Synthetic Organic Chemistry Phosphorylating and Phosphitylating Agents