ChemicalBook >> CAS DataBase List >>2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE structure

CAS No.: 5381-99-7

Chemical Name:: 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

Synonyms: 2-Chloro-4H-benzo[d][1,3,2]dioxaphosphinin-4-one;Salicyl Phosphorochloridite;2-CHLORO-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE;2-CHLORO-4H-1,2,3-BENZODIOXAPHOSPHORIN-4-ONE;SALICYLCHLOROPHOSPHITE;SalPCl;NSC 40209;VAN BOOM'S REAGENT;ChloroHbenzodioxaphosphorinone;Salicylchlorophosphite Van Boom's Reagent

CBNumber:: CB3312737

Molecular Formula:: C7H4ClO3P

Molecular Weight:: 202.53

MDL Number:: MFCD00013353

MOL File:: 5381-99-7.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Properties

Melting point	36-40 °C (lit.)
Boiling point	127-128 °C/11 mmHg (lit.)
Flash point	>230 °F
storage temp.	2-8°C
solubility	Soluble in acetonitrile, dichloromethane, tetrahydrofuron and dimethylformamide.
form	solid
color	White or Colorless to Orange to Green
BRN	1311951
Stability	Water Sensitive
CAS DataBase Reference	5381-99-7(CAS DataBase Reference)
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

Hazard Codes

Risk Statements

14-34-37

Safety Statements

26-36/37/39-43-45

RIDADR

UN 3261 8/PG 1

WGK Germany

3-10

Hazard Note

Corrosive

HazardClass

PackingGroup

HS Code

29349990

NFPA 704

	1
3		0

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	324124	2-Chloro-1,3,2-benzodioxaphosphorin-4-one 95%	5381-99-7	5g	$127	2024-03-01	Buy
Sigma-Aldrich	324124	2-Chloro-1,3,2-benzodioxaphosphorin-4-one 95%	5381-99-7	25g	$343	2024-03-01	Buy
TCI Chemical	C1210	2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one >95.0%(T)	5381-99-7	5g	$59	2024-03-01	Buy
TCI Chemical	C1210	2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one >95.0%(T)	5381-99-7	25g	$178	2024-03-01	Buy
Alfa Aesar	B21086	2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one, 97%	5381-99-7	5g	$68.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
324124	5g	$127	Buy
324124	25g	$343	Buy
C1210	5g	$59	Buy
C1210	25g	$178	Buy
B21086	5g	$68.65	Buy

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

2-Chloro-1,3,2-benzodioxaphosphorin-4-one is used as a reagent:

In the phosphorylation and phosphitylation of alcohols.
In the formation of H-phosphonates which are commonly utilized in the synthesis of nucleotides.
To synthesize nucleoside triphosphates by treating with acyl protected nucleoside.

Uses

Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs

Uses

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one is a reagent used in phosphorylation and phosphitylation of alcohols and in the formation of H-phosphonates. It is also reactive cyclic phosphitylating reagent involved in fast coupling rates and hydrolytic cleavage more readily compare to that of a acyclic analog.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE synthesis

Synthesis of 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE from Salicylic acid

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Preparation Products And Raw materials

Raw materials

4H-1,3,2-Benzodioxaphosphorin-4-one, 2-oxide Sodium acetate Salicylic acid

Preparation Products

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Suppliers

Global( 121)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21633	55
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3003	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11842	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30236	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Richest Group Ltd	58
Antai Fine Chemical Technology Co.,Limited	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-03-16	2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 5381-99-7	US $1.00-0.00 / KG	1KG	99%	20 tons	Shaanxi Dideu Medichem Co. Ltd

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one
5381-99-7
US $1.00-0.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Spectrum

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE(5381-99-7)Raman 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE(5381-99-7)IR 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE(5381-99-7)FT-IR

5381-99-7(2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE)Related Search:

NAD+ 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 2-oxide DIMETHYLCHLOROPHOSPHITE 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

VAN BOOM'S REAGENT 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE ChloroHbenzodioxaphosphorinone 2-Chloro-4H-1,2,3-benzodioxaphosphorin-4-one 90% 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE 97% NSC 40209 Salicylchlorophosphite Van Boom's Reagent 2-Chloro-4H-1,3,2-benzodioxaphosphinin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one, Salicyl chlorophosphite SalPCl 2-Chloro-1,3,2-benzodioxaphosphorin-4-one 95% 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one,97% 4H-1,3,2-Benzodioxaphosphorin-4-one,2-chloro- 2-chloro-1,3,2-benzodioxaphosphonic heterocyclohexane-4-one 2-chloro-1,3,2-benzodioxaphosphinin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphinin-4-one 95% 2-chloro-2,4-dihydro-1,3,2-benzodioxaphosphinin-4-one 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one > 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one (90%) "2-Chloro-4H-1,2,3-benzodioxaphosphorin-4-one 90%" 5381-99-7 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE C7H4ClO3P 2-Chloro-4H-benzo[d][1,3,2]dioxaphosphinin-4-one Salicyl Phosphorochloridite 2-CHLORO-4H-1,2,3-BENZODIOXAPHOSPHORIN-4-ONE 2-CHLORO-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE SALICYLCHLOROPHOSPHITE 5381-99-7 C7H4ClO3P Phosphorylating Agents Phosphorylation DNA / RNA Synthesis Catalysis and Inorganic Chemistry Phosphorus Compounds Phosphorus Precursors Phospholipids - 13C & 2H Biochemistry Nucleosides, Nucleotides & Related Reagents Phosphorylating and Phosphorothioating Agents Phosphorylation Protecting Agents, Phosphorylating Agents & Condensing Agents Synthetic Organic Chemistry Phosphorylating and Phosphitylating Agents