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2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane structure

CAS No.: 1807503-91-8

Chemical Name:: 2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane

Synonyms: AUN03918;C-NH-Boc-C-Bis-(C-PEG1-Boc);2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane;tert-butyl 3-[2-(tert-butoxycarbonylamino)-3-(3-tert-butoxy-3-oxo-propoxy)propoxy]propanoate;Propanoic acid, 3,3'-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, 1,1'-bis(1,1-dimethylethyl) ester

CBNumber:: CB33363815

Molecular Formula:: C22H41NO8

Molecular Weight:: 447.56

MDL Number:: MFCD28505566

MOL File:: 1807503-91-8.mol

Last updated:2023-02-23 14:24:01

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2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Properties

Boiling point	513.4±50.0 °C(Predicted)
Density	1.055±0.06 g/cm3(Predicted)
pka	11.51±0.46(Predicted)

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
BroadPharm	BP-22629	2-(t-Butoxycarbonylamido)-1,3-bis(t-butoxycarbonylethoxy)propane 96%	1807503-91-8	500mg	$230	2021-12-16	Buy

Product number	Packaging	Price	Buy
BP-22629	500mg	$230	Buy

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Chemical Properties,Uses,Production

Biological Activity

C-NH-Boc-C-Bis-(C-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Preparation Products And Raw materials

Raw materials

Preparation Products

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Jinan elephant international trading co., LTD		13006575422@163.com	China	6357	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1249	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Jinan elephant international trading co., LTD	58
Changzhou Furuisi Biotechnology Co., Ltd	58
Beijing Biocreative Technology Co., Ltd.	58

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane C-NH-Boc-C-Bis-(C-PEG1-Boc) Propanoic acid, 3,3'-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, 1,1'-bis(1,1-dimethylethyl) ester AUN03918 tert-butyl 3-[2-(tert-butoxycarbonylamino)-3-(3-tert-butoxy-3-oxo-propoxy)propoxy]propanoate 1807503-91-8 C22H41NO8