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Methyl 4-oxotetrahydrothiophene-3-carboxylate

Methyl 4-oxotetrahydrothiophene-3-carboxylate structure

CAS No.: 2689-68-1

Chemical Name:: Methyl 4-oxotetrahydrothiophene-3-carboxylate

Synonyms: AKOS 92615;methyl tetrahydro-4-oxo-3-thenoate;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE;3-Carbomethoxytetrahydrothiophene-4-one;METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE;METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE;Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97%;Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+%;tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester

CBNumber:: CB3354748

Molecular Formula:: C6H8O3S

Molecular Weight:: 160.19

MDL Number:: MFCD00052381

MOL File:: 2689-68-1.mol

Last updated:2023-05-16 17:00:21

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Methyl 4-oxotetrahydrothiophene-3-carboxylate Properties

Melting point	37-38 °C
Boiling point	95 °C
Density	1.309±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
solubility	Chloroform
form	Solid
pka	10.52±0.20(Predicted)
color	Light Yellow
InChI	InChI=1S/C6H8O3S/c1-9-6(8)4-2-10-3-5(4)7/h4H,2-3H2,1H3
InChIKey	LEAKUJFYXNILRB-UHFFFAOYSA-N
SMILES	C1SCC(=O)C1C(OC)=O
EPA Substance Registry System	3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester (2689-68-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319-H335
Precautionary statements	P271-P280
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
HazardClass	IRRITANT
HS Code	29339900

Methyl 4-oxotetrahydrothiophene-3-carboxylate price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	T294170	Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster	2689-68-1	5G	$440	2021-12-16	Buy
TRC	T294170	Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster	2689-68-1	25g	$1650	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0030710	METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 95.00%	2689-68-1	10G	$1320.38	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0030710	METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 95.00%	2689-68-1	1G	$631.34	2021-12-16	Buy
Medical Isotopes, Inc.	67223	Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster	2689-68-1	500mg	$650	2021-12-16	Buy

Product number	Packaging	Price	Buy
T294170	5G	$440	Buy
T294170	25g	$1650	Buy
CHM0030710	10G	$1320.38	Buy
CHM0030710	1G	$631.34	Buy
67223	500mg	$650	Buy

Methyl 4-oxotetrahydrothiophene-3-carboxylate Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

Methyl 4-oxotetrahydrothiophene-3-carboxylate is used in the preparation of a new class of neuroleptic agents.

Synthesis

2,3,4,5-Tetrahydro-4-oxo-3-thiophene carboxylic acid, methyl ester (L75a): 25.3 g (1.1 mol) of sodium were implemented in 190 mL abs. methanol to methylate. To methylate solution 70 g (0.360 mol) (L74) was added dropwise at the boiling point and the reaction mixture was heated for 45 min under reflux. The cooling mixture was poured onto a mixture of 500 mL ice and 300 mL water, acidified with 100 mL conc. HCl and the oily precipitating product was brought to crystallize under cooling with ice/sodium chloride bath. The crystals were sucked off, resumed in 100 mL methylene chloride and dried over sodium sulfate and evaporated. There were obtained 16.7 g of pale beige crystals. The aqueous phase was extracted three times with 100 mL of methylene chloride, the organic phase dried over sodium sulfate and evaporated. 30 g of crystalline product Methyl 4-oxotetrahydrothiophene-3-carboxylate was obtained. Yield: 46.7 g of light beige crystals (81 % of theory). mp 29-31 degC. TLC: Bz:MeOH:AcOH = 45:8:4, Rf = 0.75.

Methyl 4-oxotetrahydrothiophene-3-carboxylate synthesis

Synthesis of Methyl 4-oxotetrahydrothiophene-3-carboxylate from DIMETHYL 3-THIAADIPATE

Methyl 4-oxotetrahydrothiophene-3-carboxylate Preparation Products And Raw materials

Raw materials

Methyl thioglycolate Toluene Sodium Methoxide Methyl acrylate Dimethyl Thiodiglycolate

DIMETHYL 3-THIAADIPATE acrylic acid methyl ester

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Preparation Products

Cantharidin METHYL 4-AMINOTHIOPHENE-3-CARBOXYLATE METHYL 3-OXOTETRAHYDROTHIOPHENE-2-CARBOXYLATE Thieno[3,4-c]furan-1,3(4H,6H)-dione 5,7-dihydro-2-methylthieno[3,4-d]pyrimidin-4-ol

Methyl 4-oxotetrahydrothiophene-3-carboxylate Suppliers

Global( 133)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	17453	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8838	58
Xi'an Yutbon Pharmaceutical Technology Co., Ltd	029-81140587 +8618717328141	sales@yutbon.com	China	454	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Changzhou Ansciep Chemical Co., Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Xi'an Yutbon Pharmaceutical Technology Co., Ltd	58

View Lastest Price from Methyl 4-oxotetrahydrothiophene-3-carboxylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-09-23	Methyl 4-oxotetrahydrothiophene-3-carboxylate 2689-68-1	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2022-04-12	METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 2689-68-1	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
2019-12-23	METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 2689-68-1	US $1.00 / KG	1KG	85.0-99.8%	20ton	Career Henan Chemical Co

Methyl 4-oxotetrahydrothiophene-3-carboxylate
2689-68-1
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE
2689-68-1
US $1.10 / g
99.00%
Dideu Industries Group Limited

METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE
2689-68-1
US $1.00 / KG
85.0-99.8%
Career Henan Chemical Co

2689-68-1(Methyl 4-oxotetrahydrothiophene-3-carboxylate )Related Search:

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3-MERCAPTOISOBUTYRIC ACID 4-OXOTETRAHYDROTHIOPHENE-2,3-DICARBOXYLIC ACID DIMETHYL ESTER Tetrahydrothiophen-3-one 4-Mercapto-2-butanone 2-METHYL-1-BUTANETHIOL

1-(Methylthio)-2-butanone 4-METHYLTETRAHYDROTHIOPHEN-3-ONE 3-Methylthiolane METHYL 4-(METHYLTHIO)BUTYRATE

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4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE AKOS 92615 tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE methyl tetrahydro-4-oxo-3-thenoate 4-Oxo-Tetrahydro-Thiophene-3-CarboxylicAcidMethylEster 4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+% METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE Tetrahydro-4-oxo-3-thiophenecarboxylic acid methyl ester Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97% Methyl 4-oxotetrahydrothiophene-3-carboxylate , Tech. 3-(Methoxycarbonyl)-4-oxotetrahydrothiophene, 3-(Methoxycarbonyl)-4-oxothiolane Methyl 4-oxotetrahydrothiophene-3-carboxylate, technical METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE ISO 9001：2015 REACH 4-Oxytetrahydrophenol-3-carboxylic acid methyl ester 3-Carbomethoxytetrahydrothiophene-4-one 2689-68-1 KETONE Esters Thiophenes & Benzothiophenes Thiophenes & Benzothiophenes