Mesotrione
- CAS No.
- 104206-82-8
- Chemical Name:
- Mesotrione
- Synonyms
- MESOTRION;2-(4-MESYL-2-NITROBENZOYL)-1,3-CYCLOHEXANEDIONE;Weedicide Mesotrione;MESOTRIONE;Messotrione;Mesotrione 0.1;MESOTRION, PESTANAL;Mesotrione Standard;Mesotrione 100g/L SC;Mesotrione 480g/l sc
- CBNumber:
- CB3462579
- Molecular Formula:
- C14H13NO7S
- Molecular Weight:
- 339.32
- MDL Number:
- MFCD04112617
- MOL File:
- 104206-82-8.mol
| Melting point | 165° |
|---|---|
| Boiling point | 643.3±55.0 °C(Predicted) |
| Density | 1.474±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | pKa (20°): 3.12 |
| color | White to off-white |
| BRN | 8999656 |
| InChIKey | KPUREKXXPHOJQT-UHFFFAOYSA-N |
| LogP | -0.700 (est) |
| CAS DataBase Reference | 104206-82-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 48TR68G21T |
| Pesticides Freedom of Information Act (FOIA) | Mesotrione |
| EPA Substance Registry System | Mesotrione (104206-82-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361d-H373-H410 |
| Precautionary statements | P202-P260-P273-P280-P308+P313-P391 |
| Hazard Codes | N |
| Risk Statements | 50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 |
| WGK Germany | 2 |
| Toxicity | LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 in rats (mg/l): >5 by inhalation; LC50 (96 hr) in bluegill sunfish, rainbow trout (mg/l): >120, >120 |
Mesotrione price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 33855 | Mesotrione PESTANAL?, analytical standard | 104206-82-8 | 100mg | $98.8 | 2024-03-01 | Buy |
| TRC | M225765 | Mesotrione | 104206-82-8 | 1g | $215 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 59649 | Mesotrione | 104206-82-8 | 250mg | $610 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PST0000234 | MESOTRIONE 95.00% | 104206-82-8 | 5G | $909.56 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 59649 | Mesotrione | 104206-82-8 | 10g | $1375 | 2021-12-16 | Buy |
Mesotrione Chemical Properties,Uses,Production
Description
Mesotrione (2-[4-(methylsulfonyl)-2-nitrobenzoyl]-cylohexane-1,3-dione) is a selective herbicide which is also referred to as Callisto and Tenacity (trademarks). It was introduced to the market in 2001 for use in maize plantations as a control measure against grass and broad-leaved weeds. Mesotrione is a triketone herbicide which was formulated after the discovery of the naturally occurring phytotoxin leptospermone secreted by the Callistemon citrinus plant.
Chemical and Physical Properties
Mesotrione is a light yellow opaque solid with a faint pleasant odour. It dissolves at a rate of 2.2 g/l at 200 C in unbuffered water whose pH is 4.8. It also dissolves in n-heptane <0.5, xylene 1.6, toluene 3.1, methanol 4.6, ethyl acetate 18.6, 1,2-dichloroethane 66.3, acetone 93.3, and in acetonitrile 117.0, all in g/l at 200 C.
Mesotrione has a molecular weight of 339.318 g/mol, a monoisotopic mass of 339.041 g/mol and an exact mass of 339.041 g/mol. It has a heavy atom count of 23 and a complexity of 627.
Mechanism of Action
Studies indicate that the toxic influence of the compound can be attributed to high plasma concentration levels of tyrosine which is resultant of inhibition by 4-hydroxyphenylpyruvate dioxygenase (HPPD). HPPD is an essential constituent of the biochemical route that aids the conversion of tyrosine to alpha-tocopherol and plastoquino\ne.
Mesotrione is a highly potent agonist of HPPD against Arabidopsis thaliana, which is indicated by the Ki figure of c 6-18 pM. It is readily absorbed by weed species after foliar application and it is widely distributed to various parts of the plant through basipetal and acropetal movement.
Maize crops are generally tolerant to Mesotrione as a result of selective metabolism by the plant. The compound may take a relatively long time to be absorbed in some weed species hence Mesotrione is applied as a selective herbicide in maize plantations.
The plasma half-life of the compound is approximately 1 hour.
Preparation
Mesotrione is synthesized through the reaction of acetyl chloride with 3-methylmercaptonitrobenzene with aluminum trichloride as the catalyst. The relative ketone is oxidized with sodium oxychloride which results in the 4-methylsulfonyl compound, which is condensed with cyclohexane-1,3-dione to obtain the respective enol ester. The latter is reorganized to the appropriate form of the product with potassium cyanide with triethylamine as the catalyst.
Mesotrione is available as a soluble solid or concentrates, as a pressurized liquid, a ready to use solution, soluble concentrate, emulsifiable concentrate, water dispersible granules and in granular form.
Some of its premix partners may include terbuthylazine, Rimsulfron, Nicosulfron, S-Metolachlor, Glyphosphate and Atrazine.
Consumption
A study indicated that the total usage of the compound in the last 5 years is primarily in corn, which accounts for about 98% of the total acres treated and the total pounds of the applied Mesotrione. Field corn accounts for the highest percentage of the treated crops in regards to the acres treated and the acreage of crops grown at 20.2%.
Precautionary Statements
The applicator should put on protective gear when handling Mesotrione concentrate or contaminated surfaces. It is recommended that one avoids eating, drinking or smoking while handling the product and that one should always wash off any splashes that come into contact with the skin immediately.
During the application process, the sprayer should ensure that the machine is calibrated appropriately, the nozzles are in a matched set and the machine is adjusted to the respective level of the crop. The concentrates should not be left in the sprayer for extended periods of time.
Mesotrione may cause mild or acute eye irritation. However, it is not a dermal irritant.
Uses
Herbicide.
Uses
Mesotrione is a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of l epospermone.
Definition
ChEBI: An aromatic ketone that is cyclohexa-1,3-dione in which one of the hydrogens at position 2 is substituted by a 4-(methanesulfonyl)-2-nitrobenzoyl group.
Mesotrione Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12837 | 58 |
| Qingdao Trust Agri Chemical Co.,Ltd | +8613573296305 | aroma@qdtrustagri.com | China | 301 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21639 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29886 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
View Lastest Price from Mesotrione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-30 | Mesotrione
104206-82-8
|
US $123.00-52.00 / mg | 99.39% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-10-17 | Mesotrione
104206-82-8
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-08-27 | MESOTRIONE
104206-82-8
|
US $0.00 / KG | 100KG | 98 | 200TONS | qingdao trust agri chemical co.,ltd |
-
- Mesotrione
104206-82-8
- US $123.00-52.00 / mg
- 99.39%
- TargetMol Chemicals Inc.
-
- Mesotrione
104206-82-8
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- MESOTRIONE
104206-82-8
- US $0.00 / KG
- 98
- qingdao trust agri chemical co.,ltd