Z-LEHD-FMK
- CAS No.
- 210345-04-3
- Chemical Name:
- Z-LEHD-FMK
- Synonyms
- CS-1506;abs813893;Z-LEHD-FMK;CASPASE-9 INHIBITOR;Z-LE(OME)HD(OME)-FMK;CASPASE-9 INHIBITOR I;Z-LEHD-FLUOROMETHYLKETONE;Z-LEU-GLU(OME)-HIS-ASP(OME)-FMK;Z-LEHD-FMK, caspase-9 inhibitor;Z-LE(OME)HD(OME)-FLUOROMETHYLKETONE
- CBNumber:
- CB3758272
- Molecular Formula:
- C32H43FN6O10
- Molecular Weight:
- 690.73
- MDL Number:
- MFCD01862609
- MOL File:
- Mol file
Z-LEHD-FMK price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J64966 | Z-Leu-Glu(OMe)-His-Asp(OMe)-fluoromethyl ketone trifluoroacetate salt hydrate | 210345-04-3 | 1mg | $242 | 2023-06-20 | Buy |
| ApexBio Technology | B3233 | Z-LEHD-FMK | 210345-04-3 | 1mg | $259 | 2021-12-16 | Buy |
| ApexBio Technology | B3233 | Z-LEHD-FMK | 210345-04-3 | 5mg | $715 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000771 | Z-LEHD-FMK 95.00% | 210345-04-3 | 1MG | $811.34 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573379 | Z-LEHD-FMK >98% | 210345-04-3 | 100mg | $2245.7 | 2021-12-16 | Buy |
Z-LEHD-FMK Chemical Properties,Uses,Production
Uses
A cell-permeable inhibitor of caspase-9, which exhibits competitive and irreversible inhibition
Biological Activity
Cell-permeable inhibitor of caspase-9. Inhibits MG 132-induced cancer cell death and protects isolated rat hearts against ischemia-reperfusion injury. Neuroprotective following cerebral ischemia in rats in vivo .
References
[1]. ozoren n, kim k, burns tf, et al. the caspase 9 inhibitor z-lehd-fmk protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand. cancer res, 2000, 60(22): 6259-6265.
[2]. mouw g, zechel jl, zhou y, et al. caspase-9 inhibition after focal cerebral ischemia improves outcome following reversible focal ischemia. metab brain dis, 2002, 17(3): 143-151.
[3]. colak a, karaoğlan a, barut s, et al. neuroprotection and functional recovery after application of the caspase-9 inhibitor z-lehd-fmk in a rat model of traumatic spinal cord injury. j neurosurg spine, 2005, 2(3): 327-334.
Z-LEHD-FMK Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Shanghai Zhengyi Pharmaceutical Co., Ltd | 17740884366 | derek1229@163.com | China | 61 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| Jinan Trio PharmaTech Co., Ltd. | +86 (531) 88811783 | sales@trio-pharmatech.com (International market) | China | 1856 | 62 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
View Lastest Price from Z-LEHD-FMK manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Z-LEHD-fmk
210345-04-3
|
US $198.00-877.00 / mg | 96.13% | 10g | TargetMol Chemicals Inc. |
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- Z-LEHD-fmk
210345-04-3
- US $198.00-877.00 / mg
- 96.13%
- TargetMol Chemicals Inc.