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MURISTERONE A

MURISTERONE A Structure
MURISTERONE A structure
CAS No.
38778-30-2
Chemical Name:
MURISTERONE A
Synonyms
MURA;Muristerone;MURISTERONE A;Ecdysonic sterol;MURISTERONE A(P);MURISTERONE A USP/EP/BP;MURISTERONE A, IPOMOEA SPP;5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE;2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE;2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
CBNumber:
CB3781616
Molecular Formula:
C27H44O8
Molecular Weight:
496.63
MDL Number:
MFCD00056450
MOL File:
38778-30-2.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
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MURISTERONE A Properties

Boiling point 707.2±60.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO
form solid
pka 11.78±0.70(Predicted)
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

MURISTERONE A price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 11741 Muristerone A ≥95% 38778-30-2 250μg $57 2024-03-01 Buy
Cayman Chemical 11741 Muristerone A ≥95% 38778-30-2 1mg $155 2024-03-01 Buy
TRC M732780 MuristeroneA 38778-30-2 1mg $205 2021-12-16 Buy
Usbiological 255918 Muristerone A 38778-30-2 1mg $480 2021-12-16 Buy
Usbiological 045051 Muristerone A 38778-30-2 250ug $289 2021-12-16 Buy
Product number Packaging Price Buy
11741 250μg $57 Buy
11741 1mg $155 Buy
M732780 1mg $205 Buy
255918 1mg $480 Buy
045051 250ug $289 Buy

MURISTERONE A Chemical Properties,Uses,Production

Description

Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.

Uses

Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.

Biological Activity

Ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

storage

+4°C

MURISTERONE A Preparation Products And Raw materials

Raw materials

Preparation Products

MURISTERONE A Suppliers

Global( 79)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 26925 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3989 66
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9708 58
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
Dideu Industries Group Limited 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky（shanghai）International Co.,Ltd. 50
Shanghai Tauto Biotech Co., Ltd. 66
EMMX Biotechnology LLC 60
Shanghai EFE Biological Technology Co., Ltd. 58

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2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE 2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTAHYDROXY-5BETA,7-CHOLESTEN-6-ONE 2BETA,3BETA,5BETA,11ALPHA,14ALPHA,20R,22R-HEPTAHYDROXYCHOLEST-7-EN-6-ONE 5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE 5BETA,7-CHOLESTENE-2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTOL-6-ONE MurA, 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one (22R)-2β,3β,5,11α,14,20,22-Heptahydroxy-5β-cholest-7-en-6-one Ecdysonic sterol Muristerone Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2beta,3beta,5beta,11alpha,22R)- (2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one MURISTERONE A(P) (2beta,3beta,5beta,11alpha,22R)-2,3,5,11,14,20,22-Heptahydroxy-cholest-7-en-6-one MURISTERONE A MURISTERONE A, IPOMOEA SPP MURA 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one MURISTERONE A USP/EP/BP Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2β,3β,5β,11α,22R)- 38778-30-2 BioChemical Apoptosis and Cell Cycle Cell Biology Apoptosis Inducers Cell Signaling and Neuroscience Miscellaneous Natural Products