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INDEX NAME NOT YET ASSIGNED

INDEX NAME NOT YET ASSIGNED structure

CAS No.: 2365478-58-4

Chemical Name:: INDEX NAME NOT YET ASSIGNED

Synonyms: HaloPROTAC-E;(2S,4R)-N-(2-(2-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide

CBNumber:: CB39321394

Molecular Formula:: C39H56ClN5O8S

Molecular Weight:: 790.41

MDL Number:

MOL File:: 2365478-58-4.mol

Last updated:2024-07-02 08:55:07

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INDEX NAME NOT YET ASSIGNED Properties

Boiling point	983.9±65.0 °C(Predicted)
Density	1.27±0.1 g/cm3(Predicted)
pka	12.28±0.20(Predicted)
form	Oil
color	Colorless to light yellow

INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production

Description

HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14) and no other proteins were significantly degraded.

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

INDEX NAME NOT YET ASSIGNED Suppliers

Global( 13)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5225	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	3897	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62163	58
WEITIXIHAUGONG	0371-53370800 18037197114	2853031799@qq.com	China	9998	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	024-024-88590548 18341751992	757984502@qq.com	China	891	58
Wuhan Jingkangen Biomedical Technology Co., Ltd	13720134139 13720134139	orders@jknbiochem.com	China	5776	58
Shanghai Easy CDMO Co.,Ltd	021-61734564	August@easycdmo.com	China	10010	58
ZhengZhou Edward Biology Co.,Ltd	13298105281 13298105281	1522334715@qq.com	China	7511	58

Supplier	Advantage
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
Shanghai EFE Biological Technology Co., Ltd.	58
ShangHai ChuanQian Chemcial Technique Centre	58
Bide Pharmatech Ltd.	58
WEITIXIHAUGONG	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Wuhan Jingkangen Biomedical Technology Co., Ltd	58
Shanghai Easy CDMO Co.,Ltd	58
ZhengZhou Edward Biology Co.,Ltd	58

HaloPROTAC-E (2S,4R)-N-(2-(2-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide 2365478-58-4 C39H56ClN5O8S