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NPX809

CAS No.
1693734-80-3
Chemical Name:
NPX809
Synonyms
NPX800;NPX809;NXP-800;NXP-800,Heat shock proteins,NXP 800,inhibit,NXP800,CCT-361814,HSP,Inhibitor,CCT 361814;6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-fluorophenyl]-2-[(4-ethyl-1-piperazinyl)methyl]-
CBNumber:
CB410819294
Molecular Formula:
C32H32FN5O4
Molecular Weight:
569.63
MDL Number:
MOL File:
1693734-80-3.mol
Last updated:2024-07-02 08:55:07

NPX809 Properties

Boiling point 612.2±55.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (175.55 mM; Need ultrasonic)
pka 11.46±0.70(Predicted)
form Solid
color Light yellow to green yellow

NPX809 Chemical Properties,Uses,Production

Biological Activity

NXP800 (CCT361814) is a potent heat shock factor 1 (HSF1) inhibitor. NXP800 has the potential for cancer research[1]. NXP800 (example 169) inhibits U20S cells viability (IC50=0.056 μM)[1].

References

[1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1.

NPX809 Preparation Products And Raw materials

Raw materials

Preparation Products

NPX809 Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32760 60
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 950 64
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3465 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4287 55
Chengdu DingDang Pharmaceutical Co., Ltd. 028-86040038 13980902949; market@dingdangchem.com China 1850 55
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2973 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9929 58
Wuhan Sun-shine Bio-technology Corporation Limited +86-027-6552-2453 sales@sun-shinechem.com China 727 58
NPX809 NXP-800 NPX800 NXP-800,Heat shock proteins,NXP 800,inhibit,NXP800,CCT-361814,HSP,Inhibitor,CCT 361814 6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-fluorophenyl]-2-[(4-ethyl-1-piperazinyl)methyl]- 1693734-80-3