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16-PHENYL TETRANOR PROSTAGLANDIN E2

16-PHENYL TETRANOR PROSTAGLANDIN E2 Structure
16-PHENYL TETRANOR PROSTAGLANDIN E2 structure
CAS No.
38315-44-5
Chemical Name:
16-PHENYL TETRANOR PROSTAGLANDIN E2
Synonyms
DXWJXQSQVUJRNS-YYWARMNLSA-N;16-PHENYL TETRANOR PROSTAGLANDIN E2;9-OXO-11ALPHA-15S-DIHYDROXY-16-PHENYL-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-4-phenyl-1-buten-1-yl]-5-oxocyclopentyl]-, (5Z)-
CBNumber:
CB4130778
Molecular Formula:
C22H28O5
Molecular Weight:
372.45
MDL Number:
MFCD00797648
MOL File:
38315-44-5.mol
Last updated:2023-05-04 17:34:38
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16-PHENYL TETRANOR PROSTAGLANDIN E2 Properties

Boiling point 576.8±50.0 °C(Predicted)
Density 1.235±0.06 g/cm3(Predicted)
solubility DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol); Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >0.8 mg/ml
pka 4.75±0.10(Predicted)

16-PHENYL TETRANOR PROSTAGLANDIN E2 Chemical Properties,Uses,Production

Description

16-phenyl tetranor PGE2 is a metabolically stable synthetic analog of PGE2. 16-phenyl tetranor PGE2 is five times more potent than PGE2 in causing hypotension in dogs (0.1 μg/kg dose).1 It is comparable to PGE2 in inhibiting histamine-induced bronchoconstriction in conscious guinea pigs.1

Definition

ChEBI: 16-Phenyl-tetranor-PGE2 is a prostanoid.

References

1. Johnson, M.R., Schaaf, T.K., Constantine, J.W., et al. Structure activity studies leading to a tissue-selective hypotensive prostaglandin analog, 13,14-dihydro-16-phenyl-ω-tetranor PGE2 Prostaglandins 20(3),515-520(1980).

16-PHENYL TETRANOR PROSTAGLANDIN E2 Preparation Products And Raw materials

Raw materials

Preparation Products

16-PHENYL TETRANOR PROSTAGLANDIN E2 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1990 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19704 58
Supplier Advantage
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
TargetMol Chemicals Inc. 58

38315-44-5(16-PHENYL TETRANOR PROSTAGLANDIN E2)Related Search:

16-PHENYL TETRANOR PROSTAGLANDIN E2
9-OXO-11ALPHA-15S-DIHYDROXY-16-PHENYL-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID 16-PHENYL TETRANOR PROSTAGLANDIN E2 DXWJXQSQVUJRNS-YYWARMNLSA-N 5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-4-phenyl-1-buten-1-yl]-5-oxocyclopentyl]-, (5Z)- 38315-44-5