excisanin A
- CAS No.
- 78536-37-5
- Chemical Name:
- excisanin A
- Synonyms
- 1α,7α,12α,14β-Tetrahydroxykaura-16-ene-15-one;(14R)-1α,7α,12α,14-Tetrahydroxykaur-16-en-15-one;Kaur-16-en-15-one, 1,7,12,14-tetrahydroxy-, (1α,7α,12α,14R)-;1alpha,7alpha,12alpha,14beta-Tetrahydroxy-ent-kaur-16-en-15-one
- CBNumber:
- CB41308495
- Molecular Formula:
- C20H30O5
- Molecular Weight:
- 350.452
- MDL Number:
- MFCD32644906
- MOL File:
- 78536-37-5.mol
excisanin A Chemical Properties,Uses,Production
Description
Excisanin A is a diterpenoid compound purified from Isodon macrocalyxin D that has anti-cancer properties with little toxicity.
Uses
Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer[1].
References
[1] Qin J, et al. A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling. Life Sci. 2013 Nov 4;93(18-19):655-63. DOI:10.1016/j.lfs.2013.09.002
excisanin A Preparation Products And Raw materials
Raw materials
Preparation Products
excisanin A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5653 | 65 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15178 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| Guangdong wengjiang Chemical Reagent Co., Ltd. | 0751-2815688 13927872512 | 3007421951@qq.com | China | 9955 | 58 |
| Absin Bioscience Inc. | 021-38015121 18438616290 | wulan@absin.cn | China | 24731 | 58 |