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(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid

CAS No.
135042-12-5
Chemical Name:
(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid
Synonyms
BOC-D-CISHYP-OH;Boc-cis-D-Hyp-OH;cis-Boc-D-Hyp-OH;N-Boc-D-cis-Hyp-OH;N-Boc-cis-D-Hyp-OH;ATTERCOP-CHM AT700573;Boc-cis-4-hydroxy-D-proL;BOC-CIS-4-HYDROXY-D-PROLINE;N-BOC-CIS-6-HYDROXY-D-PROLINE;N-BOC-CIS-4-HYDROXY-D-PROLINE
CBNumber:
CB4141253
Molecular Formula:
C10H17NO5
Molecular Weight:
231.25
MDL Number:
MFCD02094407
MOL File:
135042-12-5.mol
Last updated:2023-04-23 13:52:06

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Properties

Melting point 146-151 °C
alpha +48~+52°(c=0.67,MeOH,24℃)
Boiling point 390.9±42.0 °C(Predicted)
Density 1.312
storage temp. 2-8°C
form powder to crystal
pka 3.80±0.40(Predicted)
color White to Light yellow
optical activity [α]22/D +50.0°, c = 1 in methanol
InChIKey BENKAPCDIOILGV-RNFRBKRXSA-N
FDA UNII I467853HPL

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
0 0

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 706574 N-Boc-cis-4-hydroxy-D-proline 97% 135042-12-5 1g $74.5 2023-06-20 Buy
TCI Chemical B5886 cis-N-(tert-Butoxycarbonyl)-4-hydroxy-D-proline 135042-12-5 1G $34 2024-03-01 Buy
TCI Chemical B5886 cis-N-(tert-Butoxycarbonyl)-4-hydroxy-D-proline 135042-12-5 5G $95 2024-03-01 Buy
TRC H945705 (2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicAcid1-(1,1-Dimethylethyl)Ester 135042-12-5 2.5g $75 2021-12-16 Buy
Usbiological 263617 N-Boc-cis-4-hydroxy-d-proline 135042-12-5 5g $337 2021-12-16 Buy
Product number Packaging Price Buy
706574 1g $74.5 Buy
B5886 1G $34 Buy
B5886 5G $95 Buy
H945705 2.5g $75 Buy
263617 5g $337 Buy

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

N-Boc-cis-4-hydroxy-D-proline can be used:

  • As a starting material in the synthesis of DNA mimicking pyrrolidine peptide nucleic acid (PNA) analog.
  • In the synthesis of biologically important macrocyclic dilactones.
  • As an intermediate in the synthesis of histamine H3?receptor antagonists.

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 210)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
GenicBio Limited
+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
HaBo Hong Kong Co., Limited.
+86-25-18512596065 info@habotech.com CHINA 933 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 17777 58
Chengdu Pukang Biotechnology Co., Ltd
028-82550498 export@pu-kang.com CHINA 210 58
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2158 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58

View Lastest Price from (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Boc-cis-4-hydroxy-D-proline pictures 2022-01-26 N-Boc-cis-4-hydroxy-D-proline
135042-12-5
US $0.00 / KG 1KG 99.5% 100 tons Honest Joy Holdings Limited
(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid pictures 2021-07-13 (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid
135042-12-5
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid pictures 2021-07-10 (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid
135042-12-5
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Spectrum

(2R,4R)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID BOC-(2R,4R)-(+)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID BOC-CIS-4-HYDROXY-D-PROLINE BOC-D-CISHYP-OH N-T-BOC-CIS-4-HYDROXY-D-PROLINE N-BOC-CIS-4-HYDROXY-D-PROLINE N-ALPHA-BUTOXYCARBONYL-CIS-4-HYDROXY-D-PROLINE N-BOC-CIS-6-HYDROXY-D-PROLINE (2r,4r)-n-boc-4-hydroxypyrrolidine-2-carboxylic acid (2R,4R)-N-BOC-4-HYDROXY-D-PROLINE (2R,4R)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic acid (2R,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (2R,4R)-N-Boc-4-hydroxy-2-pyrrolidinecarboxylic acid ATTERCOP-CHM AT700573 (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-D-proline 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) ester, (2R-cis)- Boc-cis-D-Hyp-OH cis-Boc-D-Hyp-OH N-Boc-D-cis-Hyp-OH 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) ester, (2R,4R)- N-α-(t-Butoxycarbonyl)-cis-4-hydroxy-D-proline (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid USP/EP/BP Boc-cis-4-hydroxy-D-proL cis-N-(tert-Butoxycarbonyl)-4-hydroxy-D-proline N-Boc-cis-D-Hyp-OH (2R,4R)-N-Boc-cis-4-hydroxy-D-proline (2R,4R)N-Boc-trans-4-hydroxy-D-proline N-Boc-cis-4-hydroxy-D-proline 95+% cis-N-Boc-4-hydroxy-D-proline (Tert-Butoxy)Carbonyl cis-D-Hyp-OH 1-(1,1-Dimethylethyl) (2R,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 135042-12-5 C10H17NO7