ChemicalBook >> CAS DataBase List >>NOSCAPINE HYDROCHLORIDE
NOSCAPINE HYDROCHLORIDE
- CAS No.
- 912-60-7
- Chemical Name:
- NOSCAPINE HYDROCHLORIDE
- Synonyms
- capvalhydrochloride;NOSCAPINEHCL;opianhydrochloride;noscapiniumchlorid;lyobexhydrochloride;nsc5366hydrochloride;vadebexhydrochloride;NOSCAPINE BASE / HCL;Noscapinhydrochlorid;coscopinhydrochloride
- CBNumber:
- CB4168056
- Molecular Formula:
- C22H24ClNO7
- Molecular Weight:
- 449.88
- MDL Number:
- MFCD00082546
- MOL File:
- 912-60-7.mol
Last updated:2023-06-08 17:06:36
Melting point | 221-223 °C(lit.) |
---|---|
storage temp. | 2-8°C |
solubility | Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand. |
color | Crystals |
Merck | 13,6752 |
FDA UNII | TTN62ITH9I |
NCI Drug Dictionary | noscapine hydrochloride |
EPA Substance Registry System | 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (912-60-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H336 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22 | |||||||||
Safety Statements | 36 | |||||||||
RIDADR | 1544 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | NP7225000 | |||||||||
F | 10 | |||||||||
HS Code | 2939.19.5000 | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
Toxicity | cyt-ham:fbr 60 mg/L ESKHA5 96,55,78 | |||||||||
NFPA 704 |
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NOSCAPINE HYDROCHLORIDE price More Price(22)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | N9007 | Noscapine hydrochloride hydrate analytical standard | 912-60-7 | 5g | $91 | 2024-03-01 | Buy |
Sigma-Aldrich | N9007 | Noscapine hydrochloride hydrate analytical standard | 912-60-7 | 25g | $360 | 2024-03-01 | Buy |
TCI Chemical | N0963 | Noscapine Hydrochloride Hydrate >98.0%(HPLC)(T) | 912-60-7 | 5g | $108 | 2024-03-01 | Buy |
Cayman Chemical | 17255 | Noscapine (hydrochloride) ≥98% | 912-60-7 | 1g | $56 | 2024-03-01 | Buy |
Cayman Chemical | 17255 | Noscapine (hydrochloride) ≥98% | 912-60-7 | 5g | $213 | 2024-03-01 | Buy |
NOSCAPINE HYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder or colourless crystals, hygroscopic.
Uses
Anti-Tussive
Uses
Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.
Uses
topical fluoroquinolone antibiotic for acne
Biological Activity
Opioid alkaloid with several actions. Binds to tubulin, arresting cells in mitosis and inducing apoptosis. Also is an antagonist at bradykinin receptors (pA 2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated increases in cAMP levels in CNS tissues. Clinically used antitussive agent.
Safety Profile
Poison by intravenous route.Moderately toxic by ingestion and subcutaneous routes.Mutation data reported. When heated to decomposition itemits very toxic fumes of HCl and NOx.
NOSCAPINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 145)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22883 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15354 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
Shandong Zhishang New Material Co., Ltd. | +8617653113209 | sales002@sdzschem.com | China | 3049 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
View Lastest Price from NOSCAPINE HYDROCHLORIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-06-01 | NOSCAPINE HYDROCHLORIDE USP/EP/BP
912-60-7
|
US $1.10 / g | 1g | 99.9% | 100Tons min | Dideu Industries Group Limited | ||
2020-11-16 | Noscapine Hydrochloride Hydrate
912-60-7
|
US $200.00 / KG | 1KG | 99% | 20 Tons | Longyan Tianhua Biological Technology Co., Ltd | ||
2019-07-12 | NOSCAPINE HYDROCHLORIDE
912-60-7
|
US $1.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
- NOSCAPINE HYDROCHLORIDE USP/EP/BP
912-60-7
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- Noscapine Hydrochloride Hydrate
912-60-7
- US $200.00 / KG
- 99%
- Longyan Tianhua Biological Technology Co., Ltd
- NOSCAPINE HYDROCHLORIDE
912-60-7
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
912-60-7(NOSCAPINE HYDROCHLORIDE)Related Search:
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NOSCAPINE EP STANDARD
NOSCAPINE USP STANDARD
NOSCAPINEHCL
(3S)-6,7-DIMETHOXY-3-[(5R)-5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL]-1(3H)-ISOBENZOFURANONE HYDROCHLORIDE
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]-
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI)
l-Narcotine hydrochloride
Narcotine, hydrochloride (7CI, 8CI)
NOSCAPINE BASE / HCL
Noscapine hydrate hydrochloride
6,7-Dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one hydrochloride
(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranonehydrochloride
Noscapine hydrochloride hydrate,Narcotine hydrochloride
Narcotine HCl((S,R)-Noscapine)
Noscapine HCl(Nectodon)
NoscapineHydrochlorideMonohydrate>
NOSCAPINE HYDROCHLORIDE USP/EP/BP
Noscapinhydrochlorid
capvalhydrochloride
Papaverine hydrochloride impurity A (NACOTINE HYDROCHLORIDE)
noscapiniumchlorid
912-60-7
C22H23NO7ClH
C22H23NO7HCl
C22H23NO7HClxH2O
C23H23NO7HCl
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