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NOSCAPINE HYDROCHLORIDE

CAS No.
912-60-7
Chemical Name:
NOSCAPINE HYDROCHLORIDE
Synonyms
capvalhydrochloride;NOSCAPINEHCL;opianhydrochloride;noscapiniumchlorid;lyobexhydrochloride;nsc5366hydrochloride;vadebexhydrochloride;NOSCAPINE BASE / HCL;Noscapinhydrochlorid;coscopinhydrochloride
CBNumber:
CB4168056
Molecular Formula:
C22H24ClNO7
Molecular Weight:
449.88
MDL Number:
MFCD00082546
MOL File:
912-60-7.mol
Last updated:2023-06-08 17:06:36

NOSCAPINE HYDROCHLORIDE Properties

Melting point 221-223 °C(lit.)
storage temp. 2-8°C
solubility Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand.
color Crystals
Merck 13,6752
FDA UNII TTN62ITH9I
NCI Drug Dictionary noscapine hydrochloride
EPA Substance Registry System 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (912-60-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H336
Precautionary statements  P301+P312+P330
Hazard Codes  Xn,Xi
Risk Statements  22
Safety Statements  36
RIDADR  1544
WGK Germany  3
RTECS  NP7225000
10
HS Code  2939.19.5000
HazardClass  6.1(b)
PackingGroup  III
Toxicity cyt-ham:fbr 60 mg/L ESKHA5 96,55,78
NFPA 704
0
1 0

NOSCAPINE HYDROCHLORIDE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N9007 Noscapine hydrochloride hydrate analytical standard 912-60-7 5g $91 2024-03-01 Buy
Sigma-Aldrich N9007 Noscapine hydrochloride hydrate analytical standard 912-60-7 25g $360 2024-03-01 Buy
TCI Chemical N0963 Noscapine Hydrochloride Hydrate >98.0%(HPLC)(T) 912-60-7 5g $108 2024-03-01 Buy
Cayman Chemical 17255 Noscapine (hydrochloride) ≥98% 912-60-7 1g $56 2024-03-01 Buy
Cayman Chemical 17255 Noscapine (hydrochloride) ≥98% 912-60-7 5g $213 2024-03-01 Buy
Product number Packaging Price Buy
N9007 5g $91 Buy
N9007 25g $360 Buy
N0963 5g $108 Buy
17255 1g $56 Buy
17255 5g $213 Buy

NOSCAPINE HYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals, hygroscopic.

Uses

Anti-Tussive

Uses

Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.

Uses

topical fluoroquinolone antibiotic for acne

Biological Activity

Opioid alkaloid with several actions. Binds to tubulin, arresting cells in mitosis and inducing apoptosis. Also is an antagonist at bradykinin receptors (pA 2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated increases in cAMP levels in CNS tissues. Clinically used antitussive agent.

Safety Profile

Poison by intravenous route.Moderately toxic by ingestion and subcutaneous routes.Mutation data reported. When heated to decomposition itemits very toxic fumes of HCl and NOx.

NOSCAPINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 145)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Longyan Tianhua Biological Technology Co., Ltd
0086 18039857276 18039857276 CHINA 2783 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 22883 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15354 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
Shandong Zhishang New Material Co., Ltd.
+8617653113209 sales002@sdzschem.com China 3049 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58

View Lastest Price from NOSCAPINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NOSCAPINE HYDROCHLORIDE USP/EP/BP pictures 2021-06-01 NOSCAPINE HYDROCHLORIDE USP/EP/BP
912-60-7
US $1.10 / g 1g 99.9% 100Tons min Dideu Industries Group Limited
 Noscapine Hydrochloride Hydrate pictures 2020-11-16 Noscapine Hydrochloride Hydrate
912-60-7
US $200.00 / KG 1KG 99% 20 Tons Longyan Tianhua Biological Technology Co., Ltd
NOSCAPINE HYDROCHLORIDE pictures 2019-07-12 NOSCAPINE HYDROCHLORIDE
912-60-7
US $1.00 / KG 1KG 99% 1ton Career Henan Chemical Co

NOSCAPINE HYDROCHLORIDE Spectrum

NOSCAPINE HYDROCHLORIDE NARCOTINE HYDROCHLORIDE ,3-dioxolo(4,5-g)isoquinolin-5-yl)-,hydrochloride,(s-(r*,s*))- 1(3h)isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1 1-alpha-narcotinehydrochloride coscopinhydrochloride coscotabshydrochloride key-tusscapinehydrochloride longatinhydrochloride lyobexhydrochloride methoxyhydrastinehydrochloride narcomprenhydrochloride narcosinehydrochloride nectadonhydrochloride nsc5366hydrochloride opianhydrochloride opianinehydrochloride terbenolhydrochloride tusscapinehydrochloride vadebexhydrochloride NOSCAPINE EP STANDARD NOSCAPINE USP STANDARD NOSCAPINEHCL (3S)-6,7-DIMETHOXY-3-[(5R)-5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL]-1(3H)-ISOBENZOFURANONE HYDROCHLORIDE 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]- 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI) l-Narcotine hydrochloride Narcotine, hydrochloride (7CI, 8CI) NOSCAPINE BASE / HCL Noscapine hydrate hydrochloride 6,7-Dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one hydrochloride (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranonehydrochloride Noscapine hydrochloride hydrate,Narcotine hydrochloride Narcotine HCl((S,R)-Noscapine) Noscapine HCl(Nectodon) NoscapineHydrochlorideMonohydrate> NOSCAPINE HYDROCHLORIDE USP/EP/BP Noscapinhydrochlorid capvalhydrochloride Papaverine hydrochloride impurity A (NACOTINE HYDROCHLORIDE) noscapiniumchlorid 912-60-7 C22H23NO7ClH C22H23NO7HCl C22H23NO7HClxH2O C23H23NO7HCl Analytical Standards Analytical Chromatography Product Catalog Alphabetic Chiral Building Blocks Asymmetric Synthesis Complex Molecules NJ - NZ Inhibitors