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(R)-1-Boc-3-methylpiperazine

(R)-1-Boc-3-methylpiperazine structure

CAS No.: 163765-44-4

Chemical Name:: (R)-1-Boc-3-methylpiperazine

Synonyms: tert-butyl (R)-3-methylpiperazine-1-carboxylate;(R)-4-N-BOC-2-METHYLPIPERAZINE;(R)-tert-butyl 3-Methylpiperazine-1-carboxylate;CAS:163765-44-4;(R)-4-Boc-2-Methylpi;(R)-N-BOC-2-METHYLPIPERAZINE;(R)-4-BOC-2-METHYLPIPERAZINE;(R)-1-BOC-3-METHYLPIPERAZINE;(R)-N4-BOC-2-METHYLPIPERAZINE;(3R)-1-BOC-3-METHYLPIPERAZINE

CBNumber:: CB4192376

Molecular Formula:: C10H20N2O2

Molecular Weight:: 200.28

MDL Number:: MFCD02683205

MOL File:: 163765-44-4.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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(R)-1-Boc-3-methylpiperazine Properties

Melting point	40-45 °C
Boiling point	268.7±15.0 °C(Predicted)
Density	0.997±0.06 g/cm3(Predicted)
Flash point	223 °F
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	8.52±0.40(Predicted)
form	Crystalline Powder
color	White
optical activity	[α]/D +16±2°, c = 1 in dioxane
InChIKey	FMLPQHJYUZTHQS-MRVPVSSYSA-N
CAS DataBase Reference	163765-44-4(CAS DataBase Reference)
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

37/38-41-36/37/38

Safety Statements

26-39-37/39

WGK Germany

10-34

HS Code

29335990

NFPA 704

	1
2		0

(R)-1-Boc-3-methylpiperazine price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Alfa Aesar	H27350	(R)-(+)-1-Boc-3-methylpiperazine, 97%	163765-44-4	1g	$69.65	2024-03-01	Buy
Alfa Aesar	H27350	(R)-(+)-1-Boc-3-methylpiperazine, 97%	163765-44-4	5g	$212.65	2024-03-01	Buy
Sigma-Aldrich	674761	(R)-1-Boc-3-methylpiperazine 97%	163765-44-4	1g	$90.7	2024-03-01	Buy
TRC	B656835	(R)-4-Boc-2-methylpiperazine	163765-44-4	10g	$160	2021-12-16	Buy
TRC	B656835	(R)-4-Boc-2-methylpiperazine	163765-44-4	250g	$1375	2021-12-16	Buy

Product number	Packaging	Price	Buy
H27350	1g	$69.65	Buy
H27350	5g	$212.65	Buy
674761	1g	$90.7	Buy
B656835	10g	$160	Buy
B656835	250g	$1375	Buy

(R)-1-Boc-3-methylpiperazine Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

(R)-4-Boc-2-methylpiperazine is a reagent used in organic synthesis. Used in the synthesis of orally bioavailable inhibitors of 11-β-hydroxysteroid. (R)-4-Boc-2-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

To a solution of (R)-methylpiperazine (400 mg) in dichloromethane (20 mL) at 0 ℃ was added di-tert-butyl dicarbonate (871 mg). The reaction was stirred at room temperature for 4 h and then quenched with water (20 mL), followed by extraction into dichloromethane (2 x 40 mL). The combined organics were washed with saturated aqueous brine solution (40 mL), dried (MgSO4), and concentrated to give (R)-1-Boc-3-methylpiperazine as a white solid (669 mg, 84%).

(R)-4-Boc-2-methylpiperazine

(R)-1-Boc-3-methylpiperazine synthesis

Synthesis of (R)-1-Boc-3-methylpiperazine from Di-tert-butyl dicarbonate and (R)-(-)-2-Methylpiperazine

(R)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

(R)-(-)-2-Methylpiperazine Di-tert-butyl dicarbonate 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

Preparation Products

(R)-1,2-DIMETHYL-PIPERAZINE

(R)-1-Boc-3-methylpiperazine Suppliers

Global( 285)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	7709	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29792	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	FandaChem@Gmail.com	China	8241	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32965	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29871	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	18478	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58

Supplier	Advantage
Shanghai Boc Chemical Co., Ltd.	58
Shanghai UCHEM Inc.	58
Capot Chemical Co.,Ltd.	60
Chembon Pharmaceutical Co., Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from (R)-1-Boc-3-methylpiperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-02-12	(R)-4-Boc-2-methylpiperazine 163765-44-4	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-02-08	(R)-4-Boc-2-methylpiperazine 163765-44-4	US $37.00-788.00 / g	10g	0.99	25kg	Shanghai UCHEM Inc.
2022-02-10	(R)-4-N-Boc-2-methylpiperazine 163765-44-4	US $0.00 / KG	1KG	99.3%	100 tons	Honest Joy Holdings Limited

(R)-4-Boc-2-methylpiperazine
163765-44-4
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

(R)-4-Boc-2-methylpiperazine
163765-44-4
US $37.00-788.00 / g
0.99
Shanghai UCHEM Inc.

(R)-4-N-Boc-2-methylpiperazine
163765-44-4
US $0.00 / KG
99.3%
Honest Joy Holdings Limited

(R)-1-Boc-3-methylpiperazine Spectrum

(R)-4-Boc-2-methylpiperazine(163765-44-4)¹HNMR (R)-4-Boc-2-methylpiperazine(163765-44-4)FT-IR

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(R)-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-N-BOC-2-METHYLPIPERAZINE (R)-N4-BOC-2-METHYLPIPERAZINE TERT-BUTYL (R)-3-METHYL-1-PIPERAZINECARBOXYLATE (R)-4-BOC-2-METHYLPIPERAZINE (R)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-1-BOC-3-METHYLPIPERAZINE (R)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE (R)-1-N-BOC-3-METHYLPIPERAZINE (R)-3-Methyl-1-Boc-piperazine (3R)-1-BOC-3-METHYLPIPERAZINE 4-BOC-2-(R)-METHYL-PIPERAZINE 1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3R)- (S)-1-BOC-3-METHYL-PIPERAZINE,(R)-1-Boc-3-methylpiperazine (R)-4-N-Boc-2-methylpiperazine (R )-4-N-Boc-2-methyl piperazine (R)-2-Methylpiperazine, N4-BOC protected (R)-1-Boc-3-methylpiperazine, tert-Butyl (R)-3-methyl-1-piperazinecarboxylate (R)-4-Boc-2-piperazinecarboxylic acid (R)-3-Methyl-Piperazine-1-Carbo (3R)-3-Methylpiperazine, N1-BOC protected tert-Butyl (R)-3-methyl-1-piperazinecarboxylate acid tert-Butyl (3R)-3-methylpiperazine-1-carboxylate (R)-4-N-BOC-2-METHYL-PIPERAZINE-HCl (R)-4-Boc-2-Methylpi (R)-(+)-1-Boc-3-Methylpiperazine (R)-4-N-Boc-2-Methyl-piperazine/(R)-1-Boc-3-Methylpiperazine (R)-butyl 3-Methylpiperazine-1-carboxylate (R)-(+)-1-Boc-3-methylpiperazine,97% tert-Butyl (3R)-3-methylpiperazine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-methylpiperazine (R)-4-N-BOC-2-METHYLPIPERAZINE (R)-tert-butyl 3-Methylpiperazine-1-carboxylate tert-butyl (R)-3-methylpiperazine-1-carboxylate 1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3R)- (9CI, ACI) 3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3R)- (9CI ACI) (R)-tert-butyl-2- methylpiperazine-4-carboxylate CAS:163765-44-4 163765-44-4 345-75-7 C10H20N2O2 Chiral Building Blocks Asymmetric Synthesis Heterocyclic Building Blocks Piperazines Piperaizine Piperazine series pharmacetical Piperazines