1-BENZHYDRYLPIPERAZINE
- CAS No.
- 841-77-0
- Chemical Name:
- 1-BENZHYDRYLPIPERAZINE
- Synonyms
- Diphenylmethylpiperazine;1-(DIPHENYLMETHYL)PIPERAZINE;NSC 35536;norcyclizine;AKOS NCG1-0108;AKOS BBS-00003601;TIMTEC-BB SBB003136;BENZHYDRYLPIPERAZINE;Benzhydrol piperzine;LABOTEST-BB LT00454383
- CBNumber:
- CB8117067
- Molecular Formula:
- C17H20N2
- Molecular Weight:
- 252.35
- MDL Number:
- MFCD00038379
- MOL File:
- 841-77-0.mol
| Melting point | 90-93 °C |
|---|---|
| Boiling point | 185°C/2mmHg(lit.) |
| Density | 1.0546 (rough estimate) |
| vapor pressure | 0.001Pa at 20℃ |
| refractive index | 1.5794 (estimate) |
| Flash point | 115 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 9.05±0.10(Predicted) |
| color | White to light yellow |
| Water Solubility | 0.45 g/L (20 ºC) |
| Sensitive | Air Sensitive |
| BRN | 222773 |
| LogP | 0.6 at 20℃ |
| CAS DataBase Reference | 841-77-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | NU6V5ZHD9P |
| NIST Chemistry Reference | Benzhydryl piperazine(841-77-0) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TL6465000 | |||||||||
| F | 34 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
1-BENZHYDRYLPIPERAZINE price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3760 | 1-Benzhydrylpiperazine >98.0%(GC)(T) | 841-77-0 | 5g | $84 | 2024-03-01 | Buy |
| TCI Chemical | B3760 | 1-Benzhydrylpiperazine >98.0%(GC)(T) | 841-77-0 | 25g | $251 | 2024-03-01 | Buy |
| Alfa Aesar | L11530 | 1-Benzhydrylpiperazine, 97% | 841-77-0 | 25g | $39.7 | 2024-03-01 | Buy |
| Alfa Aesar | L11530 | 1-Benzhydrylpiperazine, 97% | 841-77-0 | 100g | $85.6 | 2024-03-01 | Buy |
| TRC | B196950 | 1-Benzhydrylpiperazine | 841-77-0 | 50g | $95 | 2021-12-16 | Buy |
1-BENZHYDRYLPIPERAZINE Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystalline powder
Uses
1-(Diphenylmethyl)piperazine [N-(Diphenylmethyl)piperazine] may be used for the synthesis of 2-nitro-3,4,4-trichloro-1-(propylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene and 2-nitro-3,4,4-trichloro-1-(octadecylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene.
Uses
Cinnarizine (C465300) impurity.
Uses
1-Benzhydrylpiperazine is an intermediate used in drug synthesis
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 1098, 1955 DOI: 10.1021/ja01610a006
General Description
1-(Diphenylmethyl)piperazine is an intermediate during drug synthesis. It has been reported to be formed during the oxidative metabolism of cinnarizine (CZ) [1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine] in rat liver microsomes. It reacts with quinone in acetonitrile, followed by oxidation with an alkaline potassium ferricyanide, to afford 4-amino-3,6-di(tert-butyl)-o-benzoquinones.
Flammability and Explosibility
Not classified
1-BENZHYDRYLPIPERAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xuchang Hengsheng Pharmaceutical Co., Ltd | +86-03745692999 +86-13569491380 | xccxn@xchsyy.com | China | 15 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6383 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
View Lastest Price from 1-BENZHYDRYLPIPERAZINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | 1-Benzhydrylpiperazine
841-77-0
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-08-07 | 1-(diphenylmethyl)-piperazin
841-77-0
|
US $0.00 / Kg | 1Kg | ≥99.0% | 10 Tons | Xuchang Hengsheng Pharmaceutical Co., Ltd | |
 |
2023-04-12 | 1-BENZHYDRYLPIPERAZINE
841-77-0
|
US $1.00 / kg/bag | 1kg/bag | 99.45% | 3000 | Wuhan Dujiang Industrial Co., Ltd. |
-
- 1-Benzhydrylpiperazine
841-77-0
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 1-(diphenylmethyl)-piperazin
841-77-0
- US $0.00 / Kg
- ≥99.0%
- Xuchang Hengsheng Pharmaceutical Co., Ltd
-
- 1-BENZHYDRYLPIPERAZINE
841-77-0
- US $1.00 / kg/bag
- 99.45%
- Wuhan Dujiang Industrial Co., Ltd.
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