Pyridomycin
- CAS No.
- 18791-21-4
- Chemical Name:
- Pyridomycin
- Synonyms
- Pyridomycin;3-Hydroxy-N-[(2Z,5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-(1-methylpropylidene)-3,7,12-trioxo-9-(3-pyridylmethyl)-1,4-dioxa-8-azacyclododeca-6-yl]-2-pyridinecarboxamide;2-Pyridinecarboxamide, 3-hydroxy-N-[(2Z,5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-(1-methylpropylidene)-3,7,12-trioxo-9-(3-pyridinylmethyl)-1,4-dioxa-8-azacyclododec-6-yl]-
- CBNumber:
- CB42282882
- Molecular Formula:
- C27H32N4O8
- Molecular Weight:
- 540.57
- MDL Number:
- MFCD01690307
- MOL File:
- 18791-21-4.mol
| Melting point | 222° |
|---|---|
| Boiling point | 616.01°C (rough estimate) |
| Density | 1.3105 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble |
| pka | 11.54±0.70(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | ZTB2215O45 |
Pyridomycin price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17095 | Pyridomycin ≥95% | 18791-21-4 | 500μg | $364 | 2024-03-01 | Buy |
| Cayman Chemical | 17095 | Pyridomycin ≥95% | 18791-21-4 | 2.5mg | $1181 | 2024-03-01 | Buy |
| TRC | P997218 | Pyridomycin | 18791-21-4 | 1000μg | $395 | 2021-12-16 | Buy |
| TRC | P997218 | Pyridomycin | 18791-21-4 | 500μg | $245 | 2021-12-16 | Buy |
| Adipogen Life Sciences | BVT-0455-M001 | Pyridomycin ≥98%(1H-NMR,HPLC) | 18791-21-4 | 1mg | $290 | 2021-12-16 | Buy |
Pyridomycin Chemical Properties,Uses,Production
Description
Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-
Uses
Pyridomycin is a potent antibiotic active against mycobacteria.
Uses
Pyridomycin is a potent antibiotic active against mycobacteria and some Gram negative bacteria, originally isolated from Streptomyces abidoflavus by Umezawa group at the NIH Japan in 1953, and since isolated from different species and published under several names. The unusual 12-membered macrocyclic depsipeptide comprises three unique sub-units incorporating two substituted pyridines. Pyridomycin is thought to target NADH-dependent enoyl (acyl-carrier-protein) reductase InhA. Recent reports of activity against isoniazid-resistant mycobacteria has seen pyridomycin identified as a potential lead for new generation antibiotics.
Pyridomycin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21669 | 55 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56070 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8864 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903882 13626641628 | jiangnan@huidabiotech.com | China | 3657 | 58 |