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MK-677

CAS No.
159752-10-0
Chemical Name:
MK-677
Synonyms
IBUTAMORIN;Ibutamoren mesilate;MK677 MK 677 IBUTAMOREN;MK677(Ibutamoren Mesylate);nicotinamide mononucleotide powder;MK-677; CRESCENDO; MK 0677; MK-0677; MK0677;MK677;MK 677;MK-667;CS-1402;MK-0667;nutrobal
CBNumber:
CB42463801
Molecular Formula:
C28H40N4O8S2
Molecular Weight:
624.77
MDL Number:
MFCD00942284
MOL File:
159752-10-0.mol
MSDS File:
SDS
Last updated:2025-04-25 13:36:59

MK-677 Properties

Melting point 164-170°C
storage temp. 2-8°C
solubility H2O: soluble5mg/mL, clear
form powder
color white to beige
Water Solubility H2O: 5mg/mL, clear
InChIKey DUGMCDWNXXFHDE-VZYDHVRKSA-N
SMILES S(O)(=O)(=O)C.S(N1C2C=CC=CC=2C2(CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC3C=CC=CC=3)CC2)C1)(=O)(=O)C |&1:19,r|
FDA UNII R90JB6QJ2B
UNSPSC Code 51111800
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  TX1404490

MK-677 price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0993 MK-677 ≥98% (HPLC) 159752-10-0 5mg $150 2024-03-01 Buy
Sigma-Aldrich SML0993 MK-677 ≥98% (HPLC) 159752-10-0 25mg $627 2024-03-01 Buy
Cayman Chemical 18003 Ibutamoren (mesylate) ≥98% 159752-10-0 5mg $85 2024-03-01 Buy
Cayman Chemical 18003 Ibutamoren (mesylate) ≥98% 159752-10-0 10mg $158 2024-03-01 Buy
Cayman Chemical 18003 Ibutamoren (mesylate) ≥98% 159752-10-0 25mg $374 2024-03-01 Buy
Product number Packaging Price Buy
SML0993 5mg $150 Buy
SML0993 25mg $627 Buy
18003 5mg $85 Buy
18003 10mg $158 Buy
18003 25mg $374 Buy

MK-677 Chemical Properties,Uses,Production

Description

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Benefits

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies. 

Uses

Growth hormone releasing factor.MK-677 is a potent, non-peptide ghrelin receptor agonist.

Biochem/physiol Actions

It is also known as ibutamoren mesylate. MK-677 is a mimic of growth hormone (GH)-releasing peptide and is orally active.

Side effects

Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:
Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels, which can be controlled
When dosed properly, the side effects of MK-677 are minimal to none compared to the results you get from taking it properly. 

storage

Store at -20°C

MK-677 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 301)Suppliers
Supplier Tel Email Country ProdList Advantage
Anko Intermational Trade Limited
+86-18073326374 +86-18073326374 sales@goodpeptides.com China 58 58
Shanghai Longyu Biotechnology Co., Ltd.
+8619521488211 info@longyupharma.com China 2555 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
Shanghai Worldyang Chemical Co.,Ltd.
+86-021-56795779 +8613651600618 sales@worldyachem.com China 1227 58
Shaanxi Xianhe Biotech Co., Ltd
+8617709210191 Jerry@xhobio.com China 884 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3512 58
RongNa Biotechnology Co.,Ltd
+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3084 58
Shenzhen Monkono Technology Co.,Ltd
+86-17063441314 sansbiotech@outlook.com China 677 58
Shenzhen Aoxi Technology Co., Ltd.
+852-46424790 +852-46424790 frank88rawpowder@outlook.com China 135 58
Hebei Dangtong Import and export Co LTD
+86-86-4001020630 +8619831957301 admin@hbdangtong.com China 998 58

Related articles

  • Benefits of MK-677
  • MK-677, otherwise known as Ibutamoren Mesylate, works in the body by binding to GHSR receptors in the brain.
  • Oct 30,2019

Related Qustion

View Lastest Price from MK-677 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MK677 pictures 2025-04-27 MK677
159752-10-0
US $20.00 / kg 1kg 99.9% 10000 Hebei Miaoyin Technology Co.,Ltd
MK-677 pictures 2025-04-27 MK-677
159752-10-0
US $85.00-75.00 / box 1box 99.9% 2000box Strong peptide cross-border e-commerce Co. LTD
MK-677 pictures 2025-04-27 MK-677
159752-10-0
US $5.00 / Box 1Box 99.99% 20000 boxes Hebei Jiafan Trading Company Limited
  • MK677 pictures
  • MK677
    159752-10-0
  • US $20.00 / kg
  • 99.9%
  • Hebei Miaoyin Technology Co.,Ltd
  • MK-677 pictures
  • MK-677
    159752-10-0
  • US $85.00-75.00 / box
  • 99.9%
  • Strong peptide cross-border e-commerce Co. LTD
  • MK-677 pictures
  • MK-677
    159752-10-0
  • US $5.00 / Box
  • 99.99%
  • Hebei Jiafan Trading Company Limited
2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate (R)-1'-(2-Methylalanyl-O-benzyl-D-seryl)-1-(Methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine] Mesylate Crescendo IbutaMoren Mesylate(MK-677) MK-667 N-[1(R)-1,2-Dihydro-1-methanesulfonylspiro-3H-indole-3,4′-piperidin)-1′-yl]carbonyl-2-(phenylmethoxy)-ethyl-2-amino-2-methylpropanamide methanesulfonate MK-677(Ibutamoren) Ibutamoren, MK-0677 (R)-2-Amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidine]-1'-yl)-1-oxo Ibutamoren mesylate, >=98% CS-1402 mk677 mk 677 Ibutamoren,whnohe_lucy(at)163.com MK677,Mk677 MK-677 Selective Androgen Receptor Modulators SARMs Bodybuilding CAS 159752-10-0 2-Amino-N-[2-benzyloxy-(1R)-[1-(methanesulfonyl)spiro[indoline-3,4'-piperidin]-1'-ylcarbonyl]ethyl]isobutyramide methanesulfonate MK677(mesylate salt) Ibutamoren 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide,methanesulfonic acid MK-677 MK-677 White powder 99% China MK-677 mk 677 mk677 CAS 159752-10-0 supplier CAS NO. 159752-10-0 SARMs MK-677 Fat Burning Steroids CAS 159752-10-0 Ibutamoren For Muscle Gain MK-677,mk677,mk 677 MK677 MK-677 mk677 Sarms powder CAS NO.159752-10-0 MK-677(L163191,Ibutamoren) sarms mk 677 / mk677 ibutamoren MK677/MK-677/Ibutamoren Mesylate Ibutamoren Mesylate/MK677/MK-677 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-pip Ibutamoren mesylate (MK-677) sarms Ibutamoren Sarms 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide,methanesulfonicaci Ibuprofen mesylate (R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide methanesulfonate MK-677 USP/EP/BP Pharmaceutical Grade MK677 Ibmoren mesylate High quality MK 677 sarms MK677 powder 2-Amino-N-[2-benzyloxy-(1R)-[1-(methanesulfonyl)spiro[indoli... MK677 (MK6, Nutrobal)-1 gram(31) MK677 Synonyms: Ibutamoren Mesylate CHEMBL13817 Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, methanesulfonate (1:1) MK 0677 Ibutamoren mesylate IBUTAMORIN Ibutamoren mesilate MK677(Ibutamoren Mesylate) MK-677; CRESCENDO; MK 0677; MK-0677; MK0677;MK677;MK 677 MK677 MK 677 IBUTAMOREN nicotinamide mononucleotide powder nutrobal MK-677,Ibutamoren Mesylate, nutrobal MK677 Ibutamoren mesilate MK 0677,MK 677,Inhibitor,Ibutamoren,MK677,inhibit,Ibutamoren Mesylate,Growth hormone secretagogue receptor,GHSR,MK0677 Ibumolan mesylate MK-0667 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4&apos -piperidine]-1&apos -yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide Ibutamoren Mesylate, 10 mM in DMSO