AFC
- CAS No.
- 135304-07-3
- Chemical Name:
- AFC
- Synonyms
- AFC;AFC USP/EP/BP;AC-CYS(FARNESYL)-OH;Ac-L-Cys(Farnesyl)-OH;AC-CYSTEINE(FARNESYL)-OH;N-Acetyl-L-farnesylcysteine;n-acetyl-s-farnesylcysteine;ACETYL-S-FARNESYL-L-CYSTEINE;N-ACETYL-S-FARNESYL-L-CYSTEINE;N-ALPHA-ACETYL-S-FARNESYL-L-CYSTEINE
- CBNumber:
- CB4379892
- Molecular Formula:
- C20H33NO3S
- Molecular Weight:
- 367.55
- MDL Number:
- MFCD00871540
- MOL File:
- 135304-07-3.mol
- MSDS File:
- SDS
Boiling point | 566.1±50.0 °C(Predicted) |
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Density | 1.038±0.06 g/cm3(Predicted) |
storage temp. | -15°C |
solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) |
pka | 3.31±0.10(Predicted) |
form | Pale yellow oil. |
color | Yellow |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
LogP | 5.860 (est) |
FDA UNII | KK6984C8O3 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H225-H319-H336 | |||||||||
Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
HazardClass | IRRITANT | |||||||||
NFPA 704 |
|
AFC price More Price(22)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 63270 | N-acetyl-S-farnesyl-L-Cysteine ≥98% | 135304-07-3 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 63270 | N-acetyl-S-farnesyl-L-Cysteine ≥98% | 135304-07-3 | 5mg | $78 | 2024-03-01 | Buy |
Cayman Chemical | 63270 | N-acetyl-S-farnesyl-L-Cysteine ≥98% | 135304-07-3 | 10mg | $139 | 2024-03-01 | Buy |
Cayman Chemical | 63270 | N-acetyl-S-farnesyl-L-Cysteine ≥98% | 135304-07-3 | 25mg | $305 | 2024-03-01 | Buy |
TRC | A765560 | Arazine | 135304-07-3 | 10mg | $80 | 2021-12-16 | Buy |
AFC Chemical Properties,Uses,Production
Description
N-
Chemical Properties
Yellow-red oil
Uses
Arazine is an FTS (trans-Farnesylthiosalicylic Acid) compound, which does not inhibit EJ cell growth and does not affect Ras.
Definition
ChEBI: Acetyl-farnesyl-cysteine is a sesquiterpenoid.
References
1) Volker?et al.?(1991),?Effects of farnesylcyteine analogs on protein carboxyl methylation and signal transduction; J. Biol. Chem.?266?21515 2) Xu?et al.?(1996),?Inhibition of capacitative Ca2+ entry into cells by farnesyl analogs; Mol. Pharmacol.?50?1495 3) Rosado and Sage (2000),?Farnesylcyteine analogues inhibit store-regulated Ca2+ entry in human platelets: evidence for involvement of small GTP-binding proteins and actin cytoskeleton; Biochem. J.?347?183 4) Gordon?et al.?(2008),?Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site; J. Invest. Dermatol.?128?643 5) Adhami?et al.?(2012),?N-acetyl-S-farnesyl-L-cysteine suppresses chemokine production by human dermal microvascular endothelial cells;?Exp. Dermatol.?21?700
AFC Preparation Products And Raw materials
Raw materials
Preparation Products
AFC Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18621 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19673 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 23430 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |