NUCIFERINE
- CAS No.
- 475-83-2
- Chemical Name:
- NUCIFERINE
- Synonyms
- nuciferin;6a;VLT 049;Nuciferi;NUCIFERINE;fettuccine;Sanjoinine;Sanjoinine E;l-nuciferine;Nuciferine-RM
- CBNumber:
- CB4384597
- Molecular Formula:
- C19H21NO2
- Molecular Weight:
- 295.38
- MDL Number:
- MFCD01664592
- MOL File:
- 475-83-2.mol
| Melting point | 165.5°C |
|---|---|
| Boiling point | 437.06°C (rough estimate) |
| Density | 1.1156 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO : 11.11 mg/mL (37.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| pka | 7.87±0.20(Predicted) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D -145 to -165°, c = 0.5 in ethanol |
| LogP | 2.357 (est) |
| FDA UNII | W26UEB90B7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P330+P331+P310 | |||||||||
| Safety Statements | 24/25 | |||||||||
| RIDADR | UN 1544PSN1 6.1 / PGIII | |||||||||
| HS Code | 29389090 | |||||||||
| Toxicity | LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72 | |||||||||
| NFPA 704 |
|
NUCIFERINE price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2230 | Nuciferine ≥98% (HPLC) | 475-83-2 | 5mg | $63.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2230 | Nuciferine ≥98% (HPLC) | 475-83-2 | 25mg | $193 | 2024-03-01 | Buy |
| TCI Chemical | N1170 | Nuciferine | 475-83-2 | 250MG | $672 | 2024-03-01 | Buy |
| TCI Chemical | N1170 | Nuciferine | 475-83-2 | 50MG | $275 | 2021-12-16 | Buy |
| Sigma-Aldrich | PHL83282 | Nuciferine phyproof? Reference Substance | 475-83-2 | 10mg | $514 | 2024-03-01 | Buy |
NUCIFERINE Chemical Properties,Uses,Production
Uses
The lotus leaf alkaloid has the effect of weight loss and lipid reduction, and can be used for content determination/identification/pharmacological experiments.
Description
Nuciferine is an aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals when crystallized from EtOH. It is laevorotatory, the following specific rotations having been recorded; [α] 22D- 157.5° and - 215°. The ultraviolet spectrum has three absorption maxima at 230, 272 and 310 mp. Two methoxyl groups and one methylimino group are present and the alkaloid may be characterized as the hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The optically inactive base has been synthesized and has m.p. 136-7°C, giving a hydrochloride in the form of small colourless prisms from H20, m.p. 258°C (dec.).
Uses
Nuciferin is an drug candidate for the treatment of obesity-related diseases. It is not well studied and its pharmacokinetics in vivo have not been fully investigated.
Safety Profile
Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.
References
Gulland, Haworth., J. Chern. Soc., 590 (1928)
Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940)
Arthur, Cheung., J. Chern. Soc., 2306 (1959)
Kupchan et al., Tetrahedron, 19, 227 (1963)
NUCIFERINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8053 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567; +8618580541567 | sales@zhswyy.com | China | 303 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 380 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
View Lastest Price from NUCIFERINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-27 | NUCIFERINE (lotus?leaf extract)
475-83-2
|
US $0.00 / KG | 1KG | ≥98% HPLC | 1000KKG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-11-19 | Nuciferine
475-83-2
|
US $39.00-122.00 / mg | 99.18% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-06 | NUCIFERINE
475-83-2
|
US $0.00-0.00 / kg | 0.10000000149011612kg | ≥98% | 20tons | Chongqing Zhihe Biopharmaceutical Co., Ltd. |
-
- NUCIFERINE (lotus?leaf extract)
475-83-2
- US $0.00 / KG
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Nuciferine
475-83-2
- US $39.00-122.00 / mg
- 99.18%
- TargetMol Chemicals Inc.
-
- NUCIFERINE
475-83-2
- US $0.00-0.00 / kg
- ≥98%
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
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