TOPO II, P170 HUMAN
- CAS No.
- Chemical Name:
- TOPO II, P170 HUMAN
- Synonyms
- TOPO? II, p170;TOPO(R) II, p170;TOPO II, P170 HUMAN;TOPOISOMERASE II A HUMAN;Topoisomerase II α human
- CBNumber:
- CB4416832
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03458766
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
SAFETY
Risk and Safety Statements
| Safety Statements | 23-24/25 |
|---|---|
| WGK Germany | 1 |
TOPO II, P170 HUMAN Chemical Properties,Uses,Production
Uses
Human topoisomerase II α has been used in DNA cleavage assay.
General Description
Topoisomerase II α is encoded by TOP2A gene, which is located on 17q21.2 in the human chromosome. It is essential for controlling the topological state of DNA by reversibly breaking the DNA strands during replication, recombination and transcription. TOP2A expression increases at late S phase and during G2/M of the cell cycle and decreases after mitosis. Polymorphism with TOP2A causes chromosome instability and tumorigenesis. TOP2A causes tumor proliferation and invasiveness in various cancer types like breast cancer, ovarian cancer and prostate cancer.
Biochem/physiol Actions
Used to study DNA structure and topology.
TOPO II, P170 HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
TOPO II, P170 HUMAN Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
| Supplier | Advantage |
|---|---|
| Guangzhou Tomums Life Science Co., Ltd. | 58 |
(TOPO II, P170 HUMAN)Related Search:
TOPOISOMERASE II A HUMAN
TOPO II, P170 HUMAN
TOPO(R) II, p170
Topoisomerase II α human
TOPO? II, p170