Indole-3-carboxylic acid
- CAS No.
- 771-50-6
- Chemical Name:
- Indole-3-carboxylic acid
- Synonyms
- 1H-INDOLE-3-CARBOXYLIC ACID;ICO;3-Indoleformic acid;e-3-carboxyL;3-Indoleformic;3-CARBOXYINDOLE;3-indoleic acid;3-Indolecarboxylic;Indol-3-carbonsure;Indole-3-carboxylic
- CBNumber:
- CB4416867
- Molecular Formula:
- C9H7NO2
- Molecular Weight:
- 161.16
- MDL Number:
- MFCD00005624
- MOL File:
- 771-50-6.mol
- MSDS File:
- SDS
| Melting point | 232-234 °C (dec.)(lit.) |
|---|---|
| Boiling point | 287.44°C (rough estimate) |
| Density | 1.2480 (rough estimate) |
| refractive index | 1.5050 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in 95% Ethanol: 50 mg/ml, also soluble in methanol. |
| form | Powder |
| pka | 3.90±0.10(Predicted) |
| color | Light beige |
| BRN | 129435 |
| InChIKey | KMAKOBLIOCQGJP-UHFFFAOYSA-N |
| CAS DataBase Reference | 771-50-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 59711R38B0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-21/22 | |||||||||
| Safety Statements | 22-24/25-36/37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NK7882892 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
Indole-3-carboxylic acid price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 284734 | Indole-3-carboxylic acid ReagentPlus , 99% | 771-50-6 | 5g | $55.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 284734 | Indole-3-carboxylic acid ReagentPlus , 99% | 771-50-6 | 1g | $35 | 2023-06-20 | Buy |
| TCI Chemical | I0028 | Indole-3-carboxylic Acid >98.0%(T)(HPLC) | 771-50-6 | 5g | $54 | 2024-03-01 | Buy |
| TCI Chemical | I0028 | Indole-3-carboxylic Acid >98.0%(T)(HPLC) | 771-50-6 | 25g | $156 | 2024-03-01 | Buy |
| Alfa Aesar | A12634 | Indole-3-carboxylic acid, 98% | 771-50-6 | 1g | $23.65 | 2024-03-01 | Buy |
Indole-3-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
light beige crystalline powder (recrystallized from acetate-petroleum ether). Soluble in ethanol, ether, acetate, insoluble in boiling water, benzene, insoluble in petroleum ether.
Application
Indole-3-carboxylic Acid is a specific and competitive inhibitor of the potentiation of glycine of NMDA-gated current. Chemical reagent in the synthesis of thiadiazole derivatives used for anticancer activity.
Preparation
indole-3-carboxylic acid can be synthesized by the hydrolysis reaction of 3-trichloroacetyl indole: add 235g 3-trichloroacetyl indole into 1000ml methanol, slowly drop an appropriate amount of 50% KOH solution, heat up and reflux for 18 hours, cool to room temperature, The methanol was recovered by concentration, and the residual liquid was left; 1500 ml of water was added to the residual liquid, hydrochloric acid was added dropwise to adjust pH=3～4, and then filtered, and the solid obtained by filtration was dried to obtain 144g of indole-3-carboxylic acid crude product; The crude product was slurried with 100g of ethyl acetate for 25 minutes,filtered and dried to obtain indole-3-carboxylic acid (137g, yield 91.8%).
Definition
ChEBI: Indole-3-carboxylic acid is an indole-3-carboxylic acid carrying a carboxy group at position 3. It has a role as a human metabolite and a bacterial metabolite. It is a conjugate acid of an indole-3-carboxylate.
General Description
The structures of the derivatives of indole-3-carboxylic acid were studied using gas chromatography with high resolution mass spectrometry (GC-HRMS), ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry (UHPLC-HRMS), nuclear magnetic resonance spectroscopy (NMR) and Fourier transform infrared spectroscopy (FT-IR).
target
5-HT Receptor
Indole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8053 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9214 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
View Lastest Price from Indole-3-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | Indole-3-carboxylic acid
771-50-6
|
US $0.00-0.00 / kg | 1kg | 99%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-19 | Indole-3-carboxylic acid
771-50-6
|
US $42.00 / mg | 99.76% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-18 | 3-Indoleformic acid
771-50-6
|
US $25.00 / ASSAYS | 100ASSAYS | 99.5% | 100 mt | Hebei Weibang Biotechnology Co., Ltd |
-
- Indole-3-carboxylic acid
771-50-6
- US $0.00-0.00 / kg
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Indole-3-carboxylic acid
771-50-6
- US $42.00 / mg
- 99.76%
- TargetMol Chemicals Inc.
-
- 3-Indoleformic acid
771-50-6
- US $25.00 / ASSAYS
- 99.5%
- Hebei Weibang Biotechnology Co., Ltd