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HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE

CAS No.
19179-12-5
Chemical Name:
HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE
Synonyms
cyclo(glycylprolyl);HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE;octahydropyrrolo[1,2-a]piperazine-1,4-dione;Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-;(Pro-Gly).Hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione;2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione;Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- (6CI,7CI,8CI,9CI)
CBNumber:
CB4418533
Molecular Formula:
C7H10N2O2
Molecular Weight:
154.17
MDL Number:
MFCD01083707
MOL File:
19179-12-5.mol
Last updated:2025-04-18 09:52:23

HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Properties

Boiling point 447.9±34.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
pka 13.21±0.20(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P305+P351+P338

HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 123479 Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione 95+% 19179-12-5 1g $364 2021-12-16 Buy
AK Scientific 6826AJ Hexahydropyrrolo[1,2-A]pyrazine-1,4-dione 19179-12-5 5g $566 2021-12-16 Buy
Crysdot CD11175905 Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione 95+% 19179-12-5 5g $371 2021-12-16 Buy
Alichem 19179125 Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione 19179-12-5 5g $390 2021-12-16 Buy
Arctom CFN90272 Cyclo(Pro-Gly) 19179-12-5 10mg $332 2021-12-16 Buy
Product number Packaging Price Buy
123479 1g $364 Buy
6826AJ 5g $566 Buy
CD11175905 5g $371 Buy
19179125 5g $390 Buy
CFN90272 10mg $332 Buy

HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Chemical Properties,Uses,Production

Uses

Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2].

Definition

ChEBI: Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

in vivo

Cyclo-(Pro-Gly) (0.1 and 10 mg/kg, ip ) seems to be a memory facilitating substance and its presence in rat brain suggests the existence of a new mechanism of memory regulation[3].

References

[1] Ying-ying Sun, et al. Isolation, Purification, and Identification of Antialgal Substances in Green Alga Ulva Prolifera for Antialgal Activity Against the Common Harmful Red Tide Microalgae. Environ Sci Pollut Res Int. 2016 Jan;23(2):1449-59. DOI:10.1007/s11356-015-5377-7
[2] Fumitaka Hayasaka, et al. Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research, 22 (4), 477-483, 2016.
[3] T A Gudasheva, et al. Identification of a Novel Endogenous Memory Facilitating Cyclic Dipeptide Cyclo-Prolylglycine in Rat Brain. FEBS Lett. 1996 Aug 5;391(1-2):149-52. DOI:10.1016/0014-5793(96)00722-3

HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 19825 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12185 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10244 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514 ada@ipurechemical.com CHINA 3461 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38636 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
ForeChem (Nantong) Technology Co.,Ltd. 513-85982855 18921614129 sales@xianxingpharm.com China 3100 61
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 sales@accelachem.com China 11616 64
HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- (6CI,7CI,8CI,9CI) cyclo(glycylprolyl) 2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione octahydropyrrolo[1,2-a]piperazine-1,4-dione (Pro-Gly).Hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- 19179-12-5 PIPERIDINE PYRROLE