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Porcupine-IN-1

CAS No.
2036044-77-4
Chemical Name:
Porcupine-IN-1
Synonyms
CS-2802;PORCN-IN-1;Porcupine-IN-1;Porcn inhibitor 1;Porcupine-IN-1 free base;Porcupine,inhibit,PorcnIN1,Inhibitor,Porcn IN 1;N-((3-Fluoro-2'-methyl-[2,4'-bipyridin]-5-yl)methyl)-9H-carbazole-2-carboxamide;9H-Carbazole-2-carboxamide, N-[(3-fluoro-2'-methyl[2,4'-bipyridin]-5-yl)methyl]-
CBNumber:
CB44204130
Molecular Formula:
C25H19FN4O
Molecular Weight:
410.44
MDL Number:
MOL File:
2036044-77-4.mol
Last updated:2024-07-02 08:55:09

Porcupine-IN-1 Properties

storage temp. Store at -20°C
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: slightly soluble
form A crystalline solid
color White to off-white

SAFETY

Risk and Safety Statements

Porcupine-IN-1 price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25834 Porcupine-IN-1 ≥98% 2036044-77-4 1mg $75 2024-03-01 Buy
Cayman Chemical 25834 Porcupine-IN-1 ≥98% 2036044-77-4 5mg $281 2024-03-01 Buy
Cayman Chemical 25834 Porcupine-IN-1 ≥98% 2036044-77-4 10mg $488 2024-03-01 Buy
Cayman Chemical 25834 Porcupine-IN-1 ≥98% 2036044-77-4 25mg $938 2024-03-01 Buy
ChemScene CS-0041562 Porcn-IN-1 99.08% 2036044-77-4 10mg $250 2021-12-16 Buy
Product number Packaging Price Buy
25834 1mg $75 Buy
25834 5mg $281 Buy
25834 10mg $488 Buy
25834 25mg $938 Buy
CS-0041562 10mg $250 Buy

Porcupine-IN-1 Chemical Properties,Uses,Production

Description

Porcupine-IN-1 is an inhibitor of the Wnt and hedgehog signaling pathways (IC50s = 0.5 and 71 nM, respectively, in cell-based reporter assays). It inhibits secretion of Wnt3A from Wnt3A-transfected HEK293T cells when used at a concentration of 0.1 μM, indicating inhibition of porcupine, an enzyme that catalyzes palmitoylation of Wnt proteins.

Uses

Porcupine-IN-1, is a potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.

Porcupine-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7887 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4566 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8012 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2991 58
Shanghai Chaolan Chemical Technology Center 021-QQ:65489617 15618227136 Sales@ATKchemical.com China 7290 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
Porcupine-IN-1 PORCN-IN-1 Porcn inhibitor 1 CS-2802 9H-Carbazole-2-carboxamide, N-[(3-fluoro-2'-methyl[2,4'-bipyridin]-5-yl)methyl]- Porcupine-IN-1 free base Porcupine,inhibit,PorcnIN1,Inhibitor,Porcn IN 1 N-((3-Fluoro-2'-methyl-[2,4'-bipyridin]-5-yl)methyl)-9H-carbazole-2-carboxamide 2036044-77-4