ChemicalBook >> CAS DataBase List >>Porcupine-IN-1
Porcupine-IN-1
- CAS No.
- 2036044-77-4
- Chemical Name:
- Porcupine-IN-1
- Synonyms
- CS-2802;PORCN-IN-1;Porcupine-IN-1;Porcn inhibitor 1;Porcupine-IN-1 free base;Porcupine,inhibit,PorcnIN1,Inhibitor,Porcn IN 1;N-((3-Fluoro-2'-methyl-[2,4'-bipyridin]-5-yl)methyl)-9H-carbazole-2-carboxamide;9H-Carbazole-2-carboxamide, N-[(3-fluoro-2'-methyl[2,4'-bipyridin]-5-yl)methyl]-
- CBNumber:
- CB44204130
- Molecular Formula:
- C25H19FN4O
- Molecular Weight:
- 410.44
- MDL Number:
- MOL File:
- 2036044-77-4.mol
Last updated:2024-07-02 08:55:09
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
NFPA 704 |
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Porcupine-IN-1 price More Price(21)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 25834 | Porcupine-IN-1 ≥98% | 2036044-77-4 | 1mg | $75 | 2024-03-01 | Buy |
Cayman Chemical | 25834 | Porcupine-IN-1 ≥98% | 2036044-77-4 | 5mg | $281 | 2024-03-01 | Buy |
Cayman Chemical | 25834 | Porcupine-IN-1 ≥98% | 2036044-77-4 | 10mg | $488 | 2024-03-01 | Buy |
Cayman Chemical | 25834 | Porcupine-IN-1 ≥98% | 2036044-77-4 | 25mg | $938 | 2024-03-01 | Buy |
ChemScene | CS-0041562 | Porcn-IN-1 99.08% | 2036044-77-4 | 10mg | $250 | 2021-12-16 | Buy |
Porcupine-IN-1 Chemical Properties,Uses,Production
Description
Porcupine-IN-1 is an inhibitor of the Wnt and hedgehog signaling pathways (IC50s = 0.5 and 71 nM, respectively, in cell-based reporter assays). It inhibits secretion of Wnt3A from Wnt3A-transfected HEK293T cells when used at a concentration of 0.1 μM, indicating inhibition of porcupine, an enzyme that catalyzes palmitoylation of Wnt proteins.
Uses
Porcupine-IN-1, is a potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.
Porcupine-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 39)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4566 | 55 | |
ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8012 | 62 |
Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2991 | 58 |
Shanghai Chaolan Chemical Technology Center | 021-QQ:65489617 15618227136 | Sales@ATKchemical.com | China | 7290 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9409 | 58 |
Porcupine-IN-1
PORCN-IN-1
Porcn inhibitor 1
CS-2802
9H-Carbazole-2-carboxamide, N-[(3-fluoro-2'-methyl[2,4'-bipyridin]-5-yl)methyl]-
Porcupine-IN-1 free base
Porcupine,inhibit,PorcnIN1,Inhibitor,Porcn IN 1
N-((3-Fluoro-2'-methyl-[2,4'-bipyridin]-5-yl)methyl)-9H-carbazole-2-carboxamide
2036044-77-4