4-THIOURACIL
- CAS No.
- 591-28-6
- Chemical Name:
- 4-THIOURACIL
- Synonyms
- KC 135;4-thiouracyl;4-THIOURACIL;4-Thiouracil97%;Uracil, 4-thio-;4-Thiouracil 97%;4-Thiouracil ,98%;4-mercaptopyrimidin-2-ol;4-Thioxo-1H-pyrimidin-2-one;2-HYDROXY-4-MERCAPTOPYRIMIDINE
- CBNumber:
- CB4469328
- Molecular Formula:
- C4H4N2OS
- Molecular Weight:
- 128.15
- MDL Number:
- MFCD00090842
- MOL File:
- 591-28-6.mol
- MSDS File:
- SDS
Melting point | 295 °C (dec.) (lit.) |
---|---|
Density | 1.368 (estimate) |
refractive index | 1.7000 (estimate) |
storage temp. | Store at -20°C |
solubility | 1 M NaOH: soluble50mg/mL |
form | Powder |
pka | 5.38±0.20(Predicted) |
color | Yellow |
CAS DataBase Reference | 591-28-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332 | |||||||||
Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 20/21/22 | |||||||||
Safety Statements | 36 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 29335990 | |||||||||
NFPA 704 |
|
4-THIOURACIL price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 440736 | 4-Thiouracil 97% | 591-28-6 | 1g | $105 | 2024-03-01 | Buy |
TCI Chemical | T2757 | 4-Thiouracil >97.0%(HPLC)(T) | 591-28-6 | 1g | $137 | 2024-03-01 | Buy |
Alfa Aesar | H61919 | 4-Thiouracil, 97% | 591-28-6 | 1g | $80.65 | 2024-03-01 | Buy |
Alfa Aesar | H61919 | 4-Thiouracil, 97% | 591-28-6 | 250mg | $29.1 | 2023-06-20 | Buy |
Cayman Chemical | 16952 | 4-Thiouracil ≥98% | 591-28-6 | 1g | $88 | 2024-03-01 | Buy |
4-THIOURACIL Chemical Properties,Uses,Production
Description
4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts. It absorbs ultraviolet light >300 nm and, in the presence of oxygen, acts as an energy donor to produce singlet oxygen by triplet-triplet energy transfer. The highly reactive oxygen species then reacts readily with 4-thiouracil, leading to the production of uracil and uracil-6-sulfonate, which is fluorescent at a wavelength of ~390 nm. 4-Thiouracil is used as a T. gondii uracil phosphoribosyltransferase substrate to produce 4-thiouridine monophosphate, which can ultimately be incorporated into RNA.
Chemical Properties
yellow powder
Uses
4-Thiouracil is suitable reagent employed in Schneider′s media for the embryos during RNA extraction. It may be employed as reagent for the Northwestern blotting technique.
Uses
4-Thiouracil is a derivative of Uracil (U801000), which is a nitrogenous base in RNA nucleic acid. 4-Thiouracil is used for tagging in cell type-specific RNA isolation from intact complex tissues.
Synthesis Reference(s)
Synthesis, p. 256, 1987 DOI: 10.1055/s-1987-27906
4-THIOURACIL Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29899 | 58 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49403 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3958 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
Hunan Jibang Biological Technology Co., LTD | +8613776644403 | sales02@kingboomtech.com | China | 1806 | 58 |
View Lastest Price from 4-THIOURACIL manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-05-15 | 4-Thiouracil
591-28-6
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | ||
2019-07-06 | 4-THIOURACIL
591-28-6
|
US $1.00 / kg | 1kg | 98% | 200kg | Career Henan Chemical Co |
- 4-Thiouracil
591-28-6
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
- 4-THIOURACIL
591-28-6
- US $1.00 / kg
- 98%
- Career Henan Chemical Co
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