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α-GalCer analog 8

α-GalCer analog 8 Structure
α-GalCer analog 8 structure
CAS No.
922727-14-8
Chemical Name:
α-GalCer analog 8
Synonyms
α-GalCer analog 8;α-GalCer analog 8;α-Galactosylceramide analog 8;α-GalCer analog 8 (α-Galactosylceramide analog 8);α-D-Galactopyranoside, (2S,3S,4R)-3,4-dihydroxy-2-(4-tetracosyl-1H-1,2,3-triazol-1-yl)octadecyl
CBNumber:
CB44815381
Molecular Formula:
C50H97N3O8
Molecular Weight:
868.34
MDL Number:
MOL File:
922727-14-8.mol
Last updated:2023-05-21 10:59:17
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α-GalCer analog 8 Properties

Boiling point 928.8±75.0 °C(Predicted)
Density 1.09±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 12.92±0.70(Predicted)

α-GalCer analog 8 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26660 α-GalCer analog 8 922727-14-8 500μg $242 2024-03-01 Buy
Cayman Chemical 26660 α-GalCer analog 8 922727-14-8 1mg $378 2021-12-16 Buy
Product number Packaging Price Buy
26660 500μg $242 Buy
26660 1mg $378 Buy

α-GalCer analog 8 Chemical Properties,Uses,Production

Description

α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.1 It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 μg per animal dose, indicating a Th2 response.

References

1. Lee, T., Cho, M., Ko, S.-Y., et al. Synthesis and evaluation of 1,2,3-triazole containing analogues of the immunostimulant α-GalCer J. Med. Chem. 50(3),585-589(2007).

α-GalCer analog 8 Preparation Products And Raw materials

Raw materials

Preparation Products

α-GalCer analog 8 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29802 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Maclean Biochemical Technology Co., LTD 58
α-GalCer analog 8 α-Galactosylceramide analog 8 α-GalCer analog 8 α-D-Galactopyranoside, (2S,3S,4R)-3,4-dihydroxy-2-(4-tetracosyl-1H-1,2,3-triazol-1-yl)octadecyl α-GalCer analog 8 (α-Galactosylceramide analog 8) 922727-14-8