PIMARIC ACID
- CAS No.
- 127-27-5
- Chemical Name:
- PIMARIC ACID
- Synonyms
- Pimaric;NSC 2956;PIMARIC ACID;Pimaric Acid (>DextropiMaric Acid;Δ8(14)-PiMaric Acid;Pimaric acid (PiMA);Pimaric Acid (> 75%);Hexazinone Impurity 27;8(14),15-PiMaradien-18-oic Acid
- CBNumber:
- CB4506393
- Molecular Formula:
- C20H30O2
- Molecular Weight:
- 302.45
- MDL Number:
- MFCD28369457
- MOL File:
- 127-27-5.mol
| Melting point | 217-219° |
|---|---|
| alpha | D18 +74.7° (c = 0.4 in chloroform); D20 +87.3° (in chloroform) |
| Boiling point | bp18 282° |
| Density | 1.0434 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble,Water: soluble |
| pka | 4.68±0.60(Predicted) |
| form | Solid |
| color | White to off-white |
| LogP | 6.731 (est) |
| Indirect Additives used in Food Contact Substances | PIMARIC ACID |
| FDA 21 CFR | 175.105 |
| FDA UNII | 88R98Z71NI |
| EPA Substance Registry System | Pimaric acid (127-27-5) |
PIMARIC ACID price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26062 | Pimaric Acid | 127-27-5 | 500μg | $68 | 2022-04-27 | Buy |
| Cayman Chemical | 26062 | Pimaric Acid | 127-27-5 | 5mg | $269 | 2022-04-27 | Buy |
| Cayman Chemical | 26062 | Pimaric Acid | 127-27-5 | 1mg | $122 | 2022-04-27 | Buy |
| Usbiological | 286933 | Pimaric acid | 127-27-5 | 1mg | $582 | 2021-12-16 | Buy |
| TRC | P445100 | PimaricAcid(>75%) | 127-27-5 | 10mg | $1540 | 2021-12-16 | Buy |
PIMARIC ACID Chemical Properties,Uses,Production
Description
Pimaric acid is a resin acid that has been found in A. cordata and various pines. It reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs) in a concentration-dependent manner when used at concentrations ranging from 5 to 20 μM. Pimaric acid (10-20 μM) reduces nuclear expression and binding of the transcription factors NF-κB and AP-1 to the MMP-9 promoter in HASMCs. Pimaric acid also reduces TNF-α-induced HASMC migration to control levels when used at a concentration of 20 μg/ml.
Uses
A novel activators of large-conductance Ca2+-activated K+ channel α-subunit.
Definition
ChEBI: (+)-Pimaric acid is a diterpenoid.
PIMARIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38659 | 58 | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | thtang@dycnchem.com | China | 53900 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from PIMARIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | PIMARIC ACID
127-27-5
|
US $1.00 / KG | 1KG | 85.0-99.8% | 20 tons | Career Henan Chemical Co |
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- PIMARIC ACID
127-27-5
- US $1.00 / KG
- 85.0-99.8%
- Career Henan Chemical Co