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(R)-BAY1238097

CAS No.
1564269-85-7
Chemical Name:
(R)-BAY1238097
Synonyms
(R)-BAY1238097;(R)BAY1238097,(R) BAY1238097,(R)-BAY-1238097;3H-2,3-Benzodiazepine-3-carboxamide, 4,5-dihydro-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methyl-1-piperazinyl)phenyl]-, (4R)-
CBNumber:
CB45419641
Molecular Formula:
C25H33N5O3
Molecular Weight:
451.56
MDL Number:
MOL File:
1564269-85-7.mol
Last updated:2024-10-23 13:36:13

(R)-BAY1238097 Properties

Density 1.22±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 150 mg/mL (332.18 mM);Water : < 0.1 mg/mL (insoluble)
form Solid
pka 15.43±0.60(Predicted)
color Light yellow to yellow

(R)-BAY1238097 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 5mg $250 2021-12-16 Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 10mg $390 2021-12-16 Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 50mg $1250 2021-12-16 Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 100mg $2100 2021-12-16 Buy
Product number Packaging Price Buy
CS-0089882 5mg $250 Buy
CS-0089882 10mg $390 Buy
CS-0089882 50mg $1250 Buy
CS-0089882 100mg $2100 Buy

(R)-BAY1238097 Chemical Properties,Uses,Production

Description

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome[1][2]. BET[1].

References

[1]. Lejeune, P., et al. (2015) Abstract 3524: BAY 1238097, a novel BET inhibitor with strong efficacy in hematological tumor models. Cancer Research, 75(15 Suppl), 884. [2]. Bernasconi E, et al. Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma. Br J Haematol. 2017 Sep;178(6):936-948.

(R)-BAY1238097 Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-BAY1238097 Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29785 68
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
InvivoChem 13549236410 sales@invivochem.cn China 6753 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58

View Lastest Price from (R)-BAY1238097 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-BAY1238097 pictures 2024-10-24 (R)-BAY1238097
1564269-85-7
US $1740.00-766.00 / mg 10g TargetMol Chemicals Inc.
  • (R)-BAY1238097 pictures
  • (R)-BAY1238097
    1564269-85-7
  • US $1740.00-766.00 / mg
  • TargetMol Chemicals Inc.
(R)-BAY1238097 3H-2,3-Benzodiazepine-3-carboxamide, 4,5-dihydro-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methyl-1-piperazinyl)phenyl]-, (4R)- (R)BAY1238097,(R) BAY1238097,(R)-BAY-1238097 1564269-85-7