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Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092

CAS No.
2250261-59-5
Chemical Name:
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092
Synonyms
F092;F092 inhibitor;Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092;N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)-5-pyrimidinecarboxamide;5-Pyrimidinecarboxamide, N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)-
CBNumber:
CB46197674
Molecular Formula:
C20H17N5O2
Molecular Weight:
359.38
MDL Number:
MOL File:
2250261-59-5.mol
Last updated:2024-07-02 08:55:09

Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Properties

Boiling point 509.0±48.0 °C(Predicted)
Density 1.359±0.06 g/cm3(Predicted)
solubility DMF: 3 mg/ml; DMSO: 5 mg/ml; Ethanol: partially soluble; PBS (pH 7.2): partially soluble
form A crystalline solid
pka 10.70±0.70(Predicted)
color White to off-white

Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Chemical Properties,Uses,Production

Description

Prostaglandin D synthase (hematopoietic-type) inhibitor F092 is an inhibitor of hematopoietic-type prostaglandin D synthase (H-PGDS; KD = 0.14 nM).1

References

1. Takaya, D., Inaka, K., Omura, A., et al. Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies Bioorg. Med. Chem. 26(16),4726-4734(2018).

Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Preparation Products And Raw materials

Raw materials

Preparation Products

Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32836 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9949 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5597 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 F092 inhibitor 5-Pyrimidinecarboxamide, N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)- N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)-5-pyrimidinecarboxamide F092 2250261-59-5