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levallorphan
- CAS No.
- 152-02-3
- Chemical Name:
- levallorphan
- Synonyms
- C07069;MCL 113;Naloxiphan;Levalorfano;levallorphan;Levallorphane;Levallorphanum;17-Allylmorphinan-3-ol;N-Allyl-3-hydroxymorphinan;l-N-Allyl-3-hydroxymorphinan
- CBNumber:
- CB4928450
- Molecular Formula:
- C19H25NO
- Molecular Weight:
- 283.41
- MDL Number:
- MFCD00867732
- MOL File:
- 152-02-3.mol
Last updated:2024-03-19 15:37:51
Melting point | 180-182° |
---|---|
alpha | D20 -88.9° (c = 3 in methanol) |
Boiling point | 425.96°C (rough estimate) |
Density | 1.0260 (rough estimate) |
refractive index | 1.5000 (estimate) |
pka | 10.17±0.20(Predicted) |
FDA UNII | 353613BU4U |
levallorphan Chemical Properties,Uses,Production
Definition
ChEBI: Levallorphan is a morphinane alkaloid.
brand name
Lorfan (Roche).
Clinical Use
Levallorphan is an opioid antagonist with practically no analgesic action. It has been used as one of the first relative pure antagonists for the treatment of opioid overdosage, to reverse opioid central depression and to antagonize opioidinduced respiratory impairment . The compound is now replaced by naloxone .
Synthesis
Starting material for the levallorphan
synthesis is 1-(4-methoxybenzyl)-
1,2,3,4,5,6,7,8-octahydro isoquinoline (1)
.
Purification Methods
It crystallises from aqueous EtOH. It is a narcotic antagonist. [Schneider & Grüssner Helv Chim Acta 34 2211 1951, Hellerbach Helv Chim Acta 39 429 1956.]
levallorphan Preparation Products And Raw materials
Raw materials
Preparation Products
levallorphan Suppliers
Global( 7)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9003 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
Jinan Ruisi Pharmaceutical Technology Co., LTD | 0531-69900633 18340090523 | changyuan20@163.com | China | 1980 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
152-02-3(levallorphan)Related Search:
17-(2-propenyl)morphinan-3-ol
C07069
levallorphan
(-)-3-Hydroxy-N-allylmorphinan
17-Allylmorphinan-3-ol
2H-10,4a-Iminoethanophenanthren-6-ol, 11-allyl-1,3,4,9,10,10a-hexahydro- (6CI)
l-N-Allyl-3-hydroxymorphinan
MCL 113
Morphinan-3-ol, 17-(2-propenyl)- (9CI)
Morphinan-3-ol, 17-allyl- (8CI)
N-Allyl-3-hydroxymorphinan
Morphinan-3-ol, 17-(2-propen-1-yl)-
Levallorphane
Levallorphanum
Levalorfano
Naloxiphan
152-02-3