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(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid structure

CAS No.: 5746-03-2

Chemical Name:: (2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid

Synonyms: CEL (>70% purity);Loratadine Impurity 71;N-6-(Carboxyethyl)-L-lysine;N(6)-(1-carboxyethyl)lysine;Nε-(1-Carboxyethyl)-L-lysine;L-Lysine, N6-(1-carboxyethyl)-;N-[(5S)-5-amino-5-carboxypentyl]-DL-alanine;(2S)-2-amino-6-(1-carboxyethylamino)hexanoic acid;Nμ-(1-Carboxyethyl)-L-lysine\n(Mixture of Diastereomers);Nε-(1-Carboxyethyl)-L-lysine_x000b_(Mixture of Diastereomers)

CBNumber:: CB51112970

Molecular Formula:: C9H18N2O4

Molecular Weight:: 218.25

MDL Number:: MFCD09951918

MOL File:: 5746-03-2.mol

Last updated:2023-05-09 09:30:43

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(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Properties

Boiling point	427.7±45.0 °C(Predicted)
Density	1?+-.0.06 g/cm3(Predicted)
solubility	Water: Slightly Soluble
form	A solid
pka	2.30±0.10(Predicted)
FDA UNII	N8KUP1WS1O

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	25333	Nε-(1-Carboxyethyl)-L-lysine ≥95%	5746-03-2	1mg	$37	2024-03-01	Buy
Cayman Chemical	25333	Nε-(1-Carboxyethyl)-L-lysine ≥95%	5746-03-2	5mg	$161	2024-03-01	Buy
Cayman Chemical	25333	Nε-(1-Carboxyethyl)-L-lysine ≥95%	5746-03-2	10mg	$301	2024-03-01	Buy
TRC	C178070	Nε-(1-Carboxyethyl)-L-lysine(MixtureofDiastereomers)	5746-03-2	10mg	$160	2021-12-16	Buy
Iris Biotech GmbH	HAA2940	CEL	5746-03-2	50mg	$270	2021-12-16	Buy

Product number	Packaging	Price	Buy
25333	1mg	$37	Buy
25333	5mg	$161	Buy
25333	10mg	$301	Buy
C178070	10mg	$160	Buy
HAA2940	50mg	$270	Buy

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Chemical Properties,Uses,Production

Description

N^ε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end product (AGE) produced by the reaction of methyl glyoxal with lysine residues in proteins. Protein bound, but not free, CEL binds to the receptor for AGEs (RAGE). CEL levels are elevated in the lens of diabetic patients with cataract. Long-term caloric restriction decreases CEL levels in rat heart mitochondria. It decreases glutamate uptake and secretion of S100B in rat hippocampal slices in a RAGE-independent manner when used at a concentration of 1 mM.

Uses

CEL and CML are two stable, nonenzymatic chemical modifications of protein lysine residues resulting from glycation and oxidation reactions.

Definition

ChEBI: N(6)-(1-carboxyethyl)-L-lysine is a L-lysine derivative formed during the reaction between methylglyoxal and protein. CEL is a homologue of N(epsilon)-(carboxymethyl)lysine (CML), an advanced glycation end-product that is formed on reaction of glyoxal or glycolaldehyde with protein and on oxidative cleavage of fructoselysine, the Amadori adduct formed on glycation of protein by glucose. It is a L-lysine derivative and a non-proteinogenic L-alpha-amino acid.

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Suppliers

Global( 16)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	16168	55
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Shenzhen Regent Biochemical Technology Co., Ltd.	0755-0755-85201366 18938635012	sales@regentsciences.com	China	9305	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
ShangHai Anpel Co, Ltd.	18501792038; 18501792038	shanpel@anpel.com.cn	China	9614	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
TCI (Shanghai) Chemical Trading Co., Ltd.	021-021-61109150	sales@tcisct.com	China	31163	58
LGC Science (Shanghai) Ltd.	17717235263	cindy.yang@lgcgroup.com	China	11572	58
Shanghai Haohong Scientific Co., Ltd.	400-400-8210725	malulu@leyan.com	China	40041	58

Supplier	Advantage
Shanghai Macklin Biochemical Co.,Ltd.	55
Shanghai Kewel Chemical Co., Ltd.	50
Shenzhen Regent Biochemical Technology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
ShangHai Anpel Co, Ltd.	58
Energy Chemical	58
TCI (Shanghai) Chemical Trading Co., Ltd.	58
LGC Science (Shanghai) Ltd.	58
Shanghai Haohong Scientific Co., Ltd.	58

5746-03-2((2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid)Related Search:

NE-CARBOXYMETHYL-L-LYSINE (2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid

N(6)-(1-carboxyethyl)lysine Nε-(1-Carboxyethyl)-L-lysine (2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Nμ-(1-Carboxyethyl)-L-lysine\n(Mixture of Diastereomers) L-Lysine, N6-(1-carboxyethyl)- N-6-(Carboxyethyl)-L-lysine (2S)-2-amino-6-(1-carboxyethylamino)hexanoic acid CEL (>70% purity) Loratadine Impurity 71 N-[(5S)-5-amino-5-carboxypentyl]-DL-alanine Nε-(1-Carboxyethyl)-L-lysine_x000b_(Mixture of Diastereomers) 5746-03-2