NΕ-(1-CARBOXYETHYL)-L-LYSINE (MIXTURE OF DIASTEREOMERS) 化学特性,用途語,生産方法
説明
N
ε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end product (AGE) produced by the reaction of methyl glyoxal with lysine residues in proteins. Protein bound, but not free, CEL binds to the receptor for AGEs (RAGE). CEL levels are elevated in the lens of diabetic patients with cataract. Long-term caloric restriction decreases CEL levels in rat heart mitochondria. It decreases glutamate uptake and secretion of S100B in rat hippocampal slices in a RAGE-independent manner when used at a concentration of 1 mM.
使用
CEL and CML are two stable, nonenzymatic chemical modifications of protein lysine residues resulting from glycation and oxidation reactions.
NΕ-(1-CARBOXYETHYL)-L-LYSINE (MIXTURE OF DIASTEREOMERS) 上流と下流の製品情報
原材料
準備製品