ChemicalBook >> CAS DataBase List >>1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
- CAS No.
- 306935-41-1
- Chemical Name:
- 1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
- Synonyms
- IBC 293;IPBT-5CA;BUTTPARK 36\04-50;GPR109 receptor agonist-1;1-ISOPROPYLBENZOTRIAZOLE-5-CARBOXYLIC ACID;1-propan-2-yl-5-benzotriazolecarboxylic acid;1-propan-2-ylbenzotriazole-5-carboxylic acid;1-ISOPROPYL-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID;1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid;1-(1-METHYLETHYL)-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID
- CBNumber:
- CB5160800
- Molecular Formula:
- C10H11N3O2
- Molecular Weight:
- 205.21
- MDL Number:
- MFCD01570664
- MOL File:
- 306935-41-1.mol
Last updated:2024-11-18 17:01:59
| Melting point | 229-230°C |
|---|---|
| Boiling point | 413.9±18.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| form | Light brown solid |
| pka | 3.50±0.30(Predicted) |
| color | Off-white |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| CAS DataBase Reference | 306935-41-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15223 | IPBT-5CA ≥98% | 306935-41-1 | 50mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15223 | IPBT-5CA ≥98% | 306935-41-1 | 1g | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 15223 | IPBT-5CA ≥98% | 306935-41-1 | 100mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 15223 | IPBT-5CA ≥98% | 306935-41-1 | 500mg | $153 | 2024-03-01 | Buy |
| Tocris | 2469 | IBC293 ≥99%(HPLC) | 306935-41-1 | 10 | $96 | 2021-12-16 | Buy |
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID Chemical Properties,Uses,Production
Description
IPBT-5CA (306935-41-1) is a highly selective agonist for the human orphan G-protein-coupled receptor GPR109b (EC50 = 400 nM). No activity was reported at the highly homologous high-affinity niacin receptor GPR109a.
Definition
ChEBI: 1-propan-2-yl-5-benzotriazolecarboxylic acid is a member of benzotriazoles.
Biological Activity
Highly selective agonist for GPR109B (HM74), the human orphan G-protein-coupled receptor expressed in adipocytes. Selective for GPR109B over closely related niacin receptor GPR109A (HM74A); EC 50 values are 400 nM and > 1 μ M respectively. In vitro, inhibits isoproterenol-stimulated lipolysis in isolated human adipocytes.
References
1) Semple et al. (2006) 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b; J. Med. Chem., 49 1227
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID Suppliers
Global( 83)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7514 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32112 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11598 | 64 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 | market03@meryer.com | China | 40228 | 62 |
View Lastest Price from 1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | IBC 293
306935-41-1
|
US $44.00-118.00 / mg | 99.63% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-01 | 1-Isopropyl-1H-1,2,3-Benzotriazole-5-Carboxylic Acid
306935-41-1
|
US $104.00-597.00 / g | 1g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2020-01-10 | 1-propan-2-ylbenzotriazole-5-carboxylic acid
306935-41-1
|
US $0.01 / KG | 1KG | 98%; 99% | 500g;1kg； 25kg | Career Henan Chemical Co |
-
- IBC 293
306935-41-1
- US $44.00-118.00 / mg
- 99.63%
- TargetMol Chemicals Inc.
-
- 1-Isopropyl-1H-1,2,3-Benzotriazole-5-Carboxylic Acid
306935-41-1
- US $104.00-597.00 / g
- 0.98
- Shanghai UCHEM Inc.
-
- 1-propan-2-ylbenzotriazole-5-carboxylic acid
306935-41-1
- US $0.01 / KG
- 98%; 99%
- Career Henan Chemical Co
306935-41-1(1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID)Related Search:
Zafirlukast
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID
SC-51089
Benzotriazole-5-carboxylic acid
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1-CYCLOHEXYL-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
BUTTPARK 147\04-50
1-CYCLOBUTYL-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1-SEC-BUTYL-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1of4
BUTTPARK 36\04-50
IBC 293
IPBT-5CA
1-ISOPROPYL-1H-BENZO[D][1,2,3]TRIAZOLE-5-CARBOXYLIC ACID
1-ISOPROPYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1-ISOPROPYL-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1-ISOPROPYLBENZOTRIAZOLE-5-CARBOXYLIC ACID
1-(1-METHYLETHYL)-1H-BENZOTRIAZOLE-5-CARBOXYLIC ACID
1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid
1-(Prop-2-yl)-1H-benzotriazole-5-carboxylic acid, 5-Carboxy-1-isopropyl-1H-benzotriazole
1H-Benzotriazole-5-carboxylic acid, 1-(1-methylethyl)-
1-propan-2-yl-5-benzotriazolecarboxylic acid
1-propan-2-ylbenzotriazole-5-carboxylic acid
GPR109 receptor agonist-1
GPR109b,GPR109A,HCAR2,PUMA-G,Inhibitor,GPR109 receptor agonist-1,HCA2,inhibit,cardio-metabolic diseases,IBC 293,HM74A
306935-41-1