CARUMONAM
- CAS No.
- 87638-04-8
- Chemical Name:
- CARUMONAM
- Synonyms
- AMA 1080;CARUMONAM;Ro 17-2301;CarlliIIonaln;CARUMONAM USP/EP/BP;Ro-17-2301:A-masulin;Antibiotic Ro 17-2301;(2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid;[[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid;[[[(Z)-2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3-yl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
- CBNumber:
- CB5165269
- Molecular Formula:
- C12H14N6O10S2
- Molecular Weight:
- 466.4
- MDL Number:
- MFCD00871292
- MOL File:
- 87638-04-8.mol
- MSDS File:
- SDS
alpha | D26 -45° (c = 1 in DMSO) |
---|---|
Density | 2.13±0.1 g/cm3(Predicted) |
pka | -0.43±0.60(Predicted) |
FDA UNII | 486890PI06 |
ATC code | J01DF02 |
CARUMONAM Chemical Properties,Uses,Production
Description
Canunonam is an injectable antibiotic, the second monobactam ever developed (the first being Squibb’s aztreonam). It is highly active against Gram negative bacteria, particularly pseudomom, and is reportedly effective in the treatment of pneumonia, cystitis, peritonitis and secondary infections.
Originator
Takeda (Japan)
Definition
ChEBI: An N-sulfonated monobactam antibiotic.
brand name
Amasulin
Antimicrobial activity
A synthetic monobactam with activity against common
pathogenic organisms similar to that of aztreonam. It is resistant
to hydrolysis by the common plasmid and chromosomal
β-lactamases, but it can be hydrolyzed by ESBLs.
It is administered intravenously, achieving a concentration
of c. 78 mg/L after a 20-min infusion of 1 g. The plasma halflife
is 1.7 h and the plasma protein binding 18–28%.
Carumonam is almost entirely eliminated in the glomerular
filtrate, probenecid having no effect on excretion; 96%
of labeled compound is found in the urine, with 3% in the
feces. Between 68% and 91% of the dose appears in the urine
within 24 h.
Side effects and clinical use are similar to those of
aztreonam.
CARUMONAM Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3131 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28200 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 18958018566; | info@afinechem.com | China | 15377 | 58 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 | sales@sunlidabio.com | China | 3750 | 55 |
View Lastest Price from CARUMONAM manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-20 | CaruMonaM
87638-04-8
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | ||
2021-06-22 | CARUMONAM USP/EP/BP
87638-04-8
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | ||
2019-12-26 | CARUMONAM
87638-04-8
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
- CaruMonaM
87638-04-8
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
- CARUMONAM USP/EP/BP
87638-04-8
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- CARUMONAM
87638-04-8
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co