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Medetomidine hydrochloride

CAS No.
86347-15-1
Chemical Name:
Medetomidine hydrochloride
Synonyms
MEDETOMIDINE HYDROCHLORIDE;edetomidine;(R)-4-[1-(2;medeomidine hcl;Metetomidine HCl;Medetomidine HCl Powder;Ethyl Acetate Impurity 85;Medetomidine HCl (MPV-785);Metoclopramide (metoclopramide);Medetomidine Hydrochloride Impurities
CBNumber:
CB52130917
Molecular Formula:
C13H17ClN2
Molecular Weight:
236.74
MDL Number:
MOL File:
86347-15-1.mol
Last updated:2024-11-19 23:02:33

Medetomidine hydrochloride Properties

Melting point 164-166°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
InChI InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
InChIKey VPNGEIHDPSLNMU-UHFFFAOYSA-N
SMILES C(C1N=CNC=1)(C1C=CC=C(C)C=1C)C.Cl
FDA UNII BH210P244U

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338

Medetomidine hydrochloride price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16454 Medetomidine (hydrochloride) ≥98% 86347-15-1 5mg $62 2024-03-01 Buy
Cayman Chemical 16454 Medetomidine (hydrochloride) ≥98% 86347-15-1 10mg $96 2024-03-01 Buy
Cayman Chemical 16454 Medetomidine (hydrochloride) ≥98% 86347-15-1 50mg $388 2024-03-01 Buy
Tocris 5160 Medetomidinehydrochloride ≥99%(HPLC) 86347-15-1 50 $596 2021-12-16 Buy
Tocris 5160 Medetomidinehydrochloride ≥99%(HPLC) 86347-15-1 10 $152 2021-12-16 Buy
Product number Packaging Price Buy
16454 5mg $62 Buy
16454 10mg $96 Buy
16454 50mg $388 Buy
5160 50 $596 Buy
5160 10 $152 Buy

Medetomidine hydrochloride Chemical Properties,Uses,Production

Description

Medetomidine hydrochloride is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). It is an imidazole compound. Medetomidine hydrochloride shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). In addition, it influences the adrenergic system by mimicking the action of adrenergic neurotransmitters.

Chemical Properties

White Solid

Uses

An α2-Adrenergic agonist. Sedative; analgesic.

Uses

Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor

Definition

ChEBI: Medetomidine hydrochloride is a hydrochloride.

Biological Activity

medetomidine is a selective α2-adrenoceptor agonist, with ki of 1.08 nm, exhibts 1620-fold selectivity over α1-adrenoceptor.

Side effects

Medetomidine hydrochloride is an alpha-2 adrenoreceptor agonist. Symptoms after absorption may involve clinical effects, including dose dependent sedation, respiratory depression, bradycardia, hypotension, a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also been reported. Respiratory and haemodynamic symptoms should be treated symptomatically.

storage

Desiccate at RT

1021949-47-2
86347-15-1
Synthesis of Medetomidine hydrochloride from 5-[1-(2,3-DiMethylphenyl)ethenyl]iMidazole

Medetomidine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 232)Suppliers
Supplier Tel Email Country ProdList Advantage
Dorne Chemical Technology co. LTD
+86-86-13583358881 +8618560316533 Ethan@dornechem.com China 3095 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9414 58
Wuhan Golt Biotech Co., Ltd.
+8615389281203 maria@goltbiotech.com China 970 58
shandong perfect biotechnology co.ltd
+86-53169958659 +86-13153181156 sales@sdperfect.com China 294 58
Guangzhou Tengyue Chemical Co., Ltd.
+86-86-18148706580 +8618826483838 evan@tyvovo.com China 148 58
Shandong Huisheng Import & Export Co., Ltd.
+86-13176845580 +86-13176845580 da@zhongda-biotech.com China 232 58
Hebei Xinsheng New Material Technology Co., LTD.
+86-16632316109 xinshengkeji@xsmaterial.com China 1085 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20287 58
Shandong Hanjiang Chemical Co., Ltd
+86-0533-2066820 +8618369939125 hanson@sdhanjiang.com China 999 58
Hebei Ganmiao New material Technology Co., LTD
+86-17332992504 +86-17332992504 sales8@hbganmiao.com China 299 58

View Lastest Price from Medetomidine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Metetomidine HCl pictures 2024-11-22 Metetomidine HCl
86347-15-1
US $10.00 / ASSAYS 1ASSAYS 99% 100kg Dorne Chemical Technology co. LTD
Medetomidine hydrochloride pictures 2024-11-22 Medetomidine hydrochloride
86347-15-1
US $990.00-800.00 / ton 1ton 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Medetomidine hydrochloride pictures 2024-11-19 Medetomidine hydrochloride
86347-15-1
US $30.00-90.00 / mg 96.72% 10g TargetMol Chemicals Inc.
  • Metetomidine HCl pictures
  • Metetomidine HCl
    86347-15-1
  • US $10.00 / ASSAYS
  • 99%
  • Dorne Chemical Technology co. LTD
(r)-4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride 1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1) 5-[1-(2,3-diMethylphenyl)ethyl]-1H-IMidazole hydrochloride edetomidine Medetomidine hydrochloride (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole monohydrochloride Metetomidine HCl (R)-4-[1-(2 3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride Medetomidine (hydrochloride) cas86347-15-1 SIMS1031 Medetomidine HCl ---86347-15-1 25g 2-amino-5-(2-ethoxyanilino)-4-hydroxy-1H-pyrimidin-6-one Medetomidine Hcl Medetomidine Hydrochloride (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride USP/EP/BP Medetomidine Hydrochloride Impurities Metoclopramide (metoclopramide) medeomidine hcl Medetomidine HCl (MPV-785) MEDETOMIDINE HYDROCHLORIDE Medetomidine hydrochloride,anxiolysis,inhibit,sedation,Medetomidine,α2-adrenoceptor,MPV-785,peripheral nervous system,analgesia,MPV 785,central nervous system,Inhibitor,muscle relaxation,Beta Receptor,Adrenergic Receptor Ethyl Acetate Impurity 85 Medetomidine HCl Powder 86347-15-1 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Inhibitors