- Metetomidine HCl
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- $10.00 / 1ASSAYS
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2024-10-16
- CAS:86347-15-1
- Min. Order: 1ASSAYS
- Purity: 99%
- Supply Ability: 100kg
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| | Medetomidine hydrochloride Basic information |
| | Medetomidine hydrochloride Chemical Properties |
| Melting point | 164-166°C | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White to Off-White | | InChI | InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H | | InChIKey | VPNGEIHDPSLNMU-UHFFFAOYSA-N | | SMILES | C(C1N=CNC=1)(C1C=CC=C(C)C=1C)C.Cl |
| | Medetomidine hydrochloride Usage And Synthesis |
| Description |
Medetomidine hydrochloride is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). It is an imidazole compound. Medetomidine hydrochloride shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). In addition, it influences the adrenergic system by mimicking the action of adrenergic neurotransmitters.
| | Chemical Properties | White Solid | | Uses | An α2-Adrenergic agonist. Sedative; analgesic. | | Uses | Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor | | Definition | ChEBI: Medetomidine hydrochloride is a hydrochloride. | | Biological Activity | medetomidine is a selective α2-adrenoceptor agonist, with ki of 1.08 nm, exhibts 1620-fold selectivity over α1-adrenoceptor. | | Side effects | Medetomidine hydrochloride is an alpha-2 adrenoreceptor agonist. Symptoms after absorption may involve clinical effects, including dose dependent sedation, respiratory depression, bradycardia, hypotension, a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also been reported. Respiratory and haemodynamic symptoms should be treated symptomatically. | | storage | Desiccate at RT |
| | Medetomidine hydrochloride Preparation Products And Raw materials |
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