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5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester

CAS No.
247237-43-0
Chemical Name:
5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester
Synonyms
Tolvaptan Impurity 22;Poly(ethylene glycol) Standard (Mw 3,350);methyl 5-chloro-2-(N-(4-ethoxy-4-oxobutyl)-4-methylphenylsulfonamido)benzoate;Methyl 5-Chloro-2-[(4-ethoxy-4-oxobutyl)-(4-methylphenyl)sulfonylamino]benzoate;5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester;Benzoic acid, 5-chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]-, methyl ester;N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo [b]azepine-1-carbonyl)-3-methylphenyl)-2-methyl-N-(2-methylbenzoyl)benzamide
CBNumber:
CB52510043
Molecular Formula:
C21H24ClNO6S
Molecular Weight:
453.94
MDL Number:
MFCD16038729
MOL File:
247237-43-0.mol
MSDS File:
SDS
Last updated:2023-06-27 08:28:13

5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester Properties

Boiling point 580.4±60.0 °C(Predicted)
Density 1.30
pka -4.31±0.50(Predicted)
FDA UNII R49MW47YHC

5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M295545 Methyl5-Chloro-2-[(4-ethoxy-4-oxobutyl)-(4-methylphenyl)sulfonylamino]benzoate 247237-43-0 250mg $165 2021-12-16 Buy
American Custom Chemicals Corporation HCH0036837 5-CHLORO-2-[(3-ETHOXYCARBONYL-PROPYL)-(TOLUENE-4-SULFONYL)-AMINO]-BENZOIC ACID METHYL ESTER 95.00% 247237-43-0 5G $909.56 2021-12-16 Buy
American Custom Chemicals Corporation HCH0036837 5-CHLORO-2-[(3-ETHOXYCARBONYL-PROPYL)-(TOLUENE-4-SULFONYL)-AMINO]-BENZOIC ACID METHYL ESTER 95.00% 247237-43-0 10G $1334.03 2021-12-16 Buy
Product number Packaging Price Buy
M295545 250mg $165 Buy
HCH0036837 5G $909.56 Buy
HCH0036837 10G $1334.03 Buy

5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester Chemical Properties,Uses,Production

Uses

Methyl 5-Chloro-2-[(4-ethoxy-4-oxobutyl)-(4-methylphenyl)sulfonylamino]benzoate can be used as a reactant in the synthesis of Tolvaptan (T536650) and its intermediates. Tolvaptan is a nonpeptide arginine vasopressin (AVP) V2 receptor antagonist.

2969-81-5
247237-38-3
247237-43-0
Synthesis of 5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester from Ethyl 4-bromobutyrate and 5-Chloro-2-[[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester

5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester Suppliers

Global( 29)Suppliers
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CONIER CHEM AND PHARMA LIMITED
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Golden Pharma Co., Limited
+undefined18958062155 sales@zjgoldpharm.com China 5905 58
China National Standard Pharmaceutical Corporation Limited
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Amadis Chemical Company Limited
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Beijing Comparison Pharmaceutical Technology Co., Ltd 010-010-52878169 15801002657 sales@bjcomparison.com China 4749 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8012 62
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9592 60
Nanjing crow LuNing pharmaceutical technology co., LTD 13382066392 CHINA 4880 58
Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd. 0531-58897130 15508676053 drug_impurity@sdcclh.com China 1827 58
Shenzhen Botel Biotechnology Co. Ltd. 0755-22202135 13316968096 1979313431@qq.com China 8333 58
5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester methyl 5-chloro-2-(N-(4-ethoxy-4-oxobutyl)-4-methylphenylsulfonamido)benzoate Tolvaptan Impurity 22 Methyl 5-Chloro-2-[(4-ethoxy-4-oxobutyl)-(4-methylphenyl)sulfonylamino]benzoate Benzoic acid, 5-chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]-, methyl ester Poly(ethylene glycol) Standard (Mw 3,350) N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo [b]azepine-1-carbonyl)-3-methylphenyl)-2-methyl-N-(2-methylbenzoyl)benzamide 247237-43-0 C21H24ClNO6S