ChemicalBook >> CAS DataBase List >>5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

CAS No.
133627-17-5
Chemical Name:
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms
BIRH 414;BIRH 414 BS;Nevirapine EP Impurity A;Nevirapine Related CoMpound A;Nevirapine USP Related Compound A;11-Ethyl-4-methyl-5,11-dihydro-6H-d;Nevirapine Related Compound A (15 mg);Nevirapine EP Impurity A/ Nevirapine Related Compound A;11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
CBNumber:
CB52539709
Molecular Formula:
C14H14N4O
Molecular Weight:
254.29
MDL Number:
MFCD27967300
MOL File:
133627-17-5.mol
MSDS File:
SDS
Last updated:2022-12-21 16:56:50

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Properties

Melting point 212-214℃ (1,2-dichloroethane )
Boiling point 389.8±42.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
pka 12.05±0.20(Predicted)
FDA UNII O3PEN5V8WL

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H317-H373
Precautionary statements  P260-P280-P301+P330+P331+P310
HS Code  2933997500

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1460725 Nevirapine Related Compound A United States Pharmacopeia (USP) Reference Standard 133627-17-5 15MG $1300 2024-03-01 Buy
TRC B399700 BIRH414 133627-17-5 100mg $1510 2021-12-16 Buy
Usbiological 162856 BIRH 414 133627-17-5 10mg $502 2021-12-16 Buy
AvaChem 3831 Nevirapine Impurity A 133627-17-5 25mg $575 2021-12-16 Buy
AvaChem 3831 Nevirapine Impurity A 133627-17-5 5mg $175 2021-12-16 Buy
Product number Packaging Price Buy
1460725 15MG $1300 Buy
B399700 100mg $1510 Buy
162856 10mg $502 Buy
3831 25mg $575 Buy
3831 5mg $175 Buy

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemical Properties,Uses,Production

Uses

BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme. This is also an impurity found in Nevirapine (N391275).

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Preparation Products And Raw materials

Raw materials

Preparation Products

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Suppliers

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Nevirapine Related CoMpound A Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one) BIRH 414 11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one BIRH 414 BS Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one} 11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Nevirapine EP Impurity A/ Nevirapine Related Compound A Nevirapine Related Compound A (15 mg) 6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-ethyl-5,11-dihydro-4-methyl- 11-Ethyl-4-methyl-5,11-dihydro-6H-d Nevirapine EP Impurity A 11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one Nevirapine impurity Ⅱ {11-ethyl-4-methyl-5,11-dihydr o-6H-dipyrido[3,2-b:2′,3′ -e][1,4] diazepin-6-one} Nevirapine USP Related Compound A Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 11-Ethyl-4-methyl-5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 133627-17-5 25429 Pharmaceuticals, Intermediates & Fine Chemicals