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4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline

CAS No.
630125-91-6
Chemical Name:
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline
Synonyms
4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)aniline;4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline;Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-
CBNumber:
CB52627024
Molecular Formula:
C14H20F3N3
Molecular Weight:
287.32
MDL Number:
MFCD09909923
MOL File:
630125-91-6.mol
MSDS File:
SDS
Last updated:2023-05-15 10:44:02

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Properties

Boiling point 344.9±42.0 °C(Predicted)
Density 1.195±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility soluble in Dichloromethane;
form Solid
pka 7.76±0.10(Predicted)
color Yellow

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E924295 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine 630125-91-6 50mg $430 2021-12-16 Buy
TRC E924295 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine 630125-91-6 250mg $1850 2021-12-16 Buy
ChemScene CS-M1925 4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline 99.10% 630125-91-6 1g $303 2021-12-16 Buy
ChemScene CS-M1925 4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline 99.10% 630125-91-6 10g $1519 2021-12-16 Buy
Matrix Scientific 183114 4-(4-Ethylpiperazin-1-ylmethyl)-3-trifluoromethylphenylamine 95% 630125-91-6 2.500g $1568 2021-12-16 Buy
Product number Packaging Price Buy
E924295 50mg $430 Buy
E924295 250mg $1850 Buy
CS-M1925 1g $303 Buy
CS-M1925 10g $1519 Buy
183114 2.500g $1568 Buy

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Chemical Properties,Uses,Production

Uses

4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N''-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Cochemical Co. Ltd.
+86-029-86115547 +86-17791676824 sales@cochemical.com China 3952 58
Allfluoro pharmaceutical co. ltd.
+86-400-0216110 +86-15958047586 sales@allfluoro.com China 11385 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7552 61
Changzhou Chemscaler Pharmtech Co., Ltd. 0519-81096292 15312577869 chemscaler@yahoo.com.cn China 307 60
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3016 58
Bide Pharmatech Ltd. 400-164-7117 13681763483 product02@bidepharm.com China 41457 60
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)aniline Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)- 630125-91-6 3630125-91-6