Paraffin, liquid
- CAS No.
- 8012-95-1
- Chemical Name:
- Paraffin, liquid
- Synonyms
- Paraffin oil;LIQUID PARAFFIN;OIL;PARAFFIN LIQUID;NUJOL;paraffins;drakeol;fonoline;LIGHT WHITE OIL;LIQUID PETROLATUM
- CBNumber:
- CB5266104
- Molecular Formula:
- unspecified
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131611
- MOL File:
- Mol file
| Melting point | -24 °C (lit.) |
|---|---|
| Boiling point | 300 °C (lit.) |
| Density | 0.827-0.890 g/mL at 20 °C |
| refractive index |
n |
| Flash point | >300°C |
| storage temp. | Store at room temperature. |
| solubility | Practically insoluble in ethanol (95%), glycerin, and water; soluble in acetone, benzene, chloroform, carbon disulfide, ether, and petroleum ether. Miscible with volatile oils and fixed oils, with the exception of castor oil. |
| form | light oil |
| color | white |
| Specific Gravity | 0.870 (20/4℃) |
| Odor | Odorless |
| Water Solubility | Soluble in ether. Sparingly soluble in ethanol. Not miscible or difficult to mix in water. |
| Merck | 14,7023 |
| Exposure limits |
ACGIH: TWA 5 mg/m3 OSHA: TWA 5 mg/m3 NIOSH: IDLH 2500 mg/m3; TWA 5 mg/m3; STEL 10 mg/m3 |
| Dielectric constant | 2.0（Ambient） |
| Substances Added to Food (formerly EAFUS) | MINERAL OIL, WHITE |
| FDA UNII | T5L8T28FGP |
| EPA Substance Registry System | Paraffin oils (8012-95-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H304 | |||||||||
| Precautionary statements | P301+P310-P331-P405-P501 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 36-51/53 | |||||||||
| Safety Statements | 26-61 | |||||||||
| OEB | B | |||||||||
| OEL | TWA: 5 mg/m3, STEL: 10 mg/m3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | PY8030000 | |||||||||
| Autoignition Temperature | 245°C | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 27122090 | |||||||||
| Toxicity | LD50 oral in rat: > 24gm/kg | |||||||||
| IDLA | 2,500 mg/m3 | |||||||||
| NFPA 704 |
|
Paraffin, liquid price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PX0047 | Paraffin Oil Light | 8012-95-1 | 500ML | $49.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | PX0047 | Paraffin Oil Light | 8012-95-1 | 20L | $394 | 2024-03-01 | Buy |
| Sigma-Aldrich | PX0046 | Paraffin Oil heavy | 8012-95-1 | 500ML | $77.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 18512 | Paraffin oil puriss., meets analytical specification of Ph. Eur., BP, viscous liquid | 8012-95-1 | 1l | $98.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1443952 | Mineral oil United States Pharmacopeia (USP) Reference Standard | 8012-95-1 | 1.5ml | $474 | 2024-03-01 | Buy |
Paraffin, liquid Chemical Properties,Uses,Production
Description
Mineral oil mist is a colorless, oily liquid aero-sol dispersed in air with an odor like burned lubricating oil.The odor threshold is 1.0 ppm. Specific gravity (H2O:1)=0.865 at 60℃; Boiling point = 250- 360*C; Vaporpressure = <0.5 mmHg at 20℃; Flash point= 193℃;Autoignition temperature = 260- 371℃. HazardIdentification (based on NFPA-704 M Rating System):Health 0, Flammability 1, Reactivity 0. Insoluble in water.
Chemical Properties
Mineral oil is a transparent, colorless, viscous oily liquid, without fluorescence in daylight. It is practically tasteless and odorless when cold, and has a faint odor of petroleum when heated.
Chemical Properties
Clear colorless oil
Uses
Mineral oil is a lubricant and is used as a solvent for inks in the printing industry.
Uses
Laxative; pharmaceutic aid (solvent).
Uses
Paraffin Oils is a useful organic solvent for isolating the nucleus of the gian amphibian oocyte.
Production Methods
Mineral oil is obtained by distillation of petroleum. The lighter hydrocarbons are first removed by distillation and the residue is then redistilled between 330–390°C. The distillate is chilled and the solid fractions are removed by filtration. The filtrate is then further purified and decolorized by high-pressure hydrogenation or sulfuric acid treatment; the purified filtrate is then filtered through adsorbents. The liquid portion obtained is distilled and the portion boiling below 360°C is discarded. A suitable stabilizer may be added to the mineral oil;
Definition
Liquid hydrocarbons from petroleum.
brand name
Balneol (Solvay Pharmaceuticals); Neo-Cultol (Fisons); Nujol (Schering-Plough HealthCare).
General Description
Transparent colorless oily liquid. Practically tasteless and odorless, even when warmed.
Air & Water Reactions
Flammable. Insoluble in water.
Reactivity Profile
OIL. [MINERAL] may be incompatible with strong oxidizing agents like nitric acid. Charring may occur followed by ignition of unreacted oil and other nearby combustibles. In other settings, mostly unreactive. Not affected by aqueous solutions of acids, alkalis, most oxidizing agents, and most reducing agents. Burns exothermically when heated sufficiently or when ignited in the presence of air, oxygen or strong oxidizing agents.
Hazard
Inhalation of vapor or particulates can causeaspiration pneumonia. Combustible liquid. Upperrespiratory tract irritant. Questionable carcinogen.
Health Hazard
Highly refined mineral oil mist is of low toxicity.
Fire Hazard
PARAFFIN is combustible.
Pharmaceutical Applications
Mineral oil is used primarily as an excipient in topical pharmaceutical
formulations, where its emollient properties are exploited as an
ingredient in ointment bases. It is additionally used in
oil-in-water emulsions,as a solvent, and as a lubricant in
capsule and tablet formulations, and to a limited extent as a mold-release agent for cocoa butter suppositories. It has also been used in
the preparation of microspheres and as a vaccine adjunct.
Therapeutically, mineral oil has been used as a laxative.It is indigestible and thus has limited absorption.
Mineral oil is used in ophthalmic formulations for its lubricant
properties. It is also used in cosmetics and some food products.
Safety Profile
A human teratogen by inhalation that causes testicular tumors in the fetus. Inhalation of vapor or particulates can cause aspiration pneumonia. A skin and eye irritant. Highly purified food grades are of low toxicity. Questionable human carcinogen producing gastrointestinal tumors. Slightly combustible liquid when exposed to heat or flame. To fight fire, use dry chemical, CO2, foam. When heated to decomposition it emits acrid smoke and fumes.
Safety
Mineral oil is used as an excipient in a wide variety of
pharmaceutical formulations. It is also used in
cosmetics and in some food products.
Therapeutically, mineral oil has been used in the treatment of
constipation, as it acts as a lubricant and stool softener when taken
orally. Daily doses of up to 45mL have been administered orally,
while doses of up to 120mL have been used as an enema. However,
excessive dosage of mineral oil, either orally or rectally, can result in
anal seepage and irritation, and its oral use as a laxative is not
considered desirable.
Chronic oral consumption of mineral oil may impair the appetite
and interfere with the absorption of fat-soluble vitamins. Prolonged
use should be avoided. Mineral oil is absorbed to some extent when
emulsified and can lead to granulomatous reactions. Similar
reactions also occur upon injection of the oil;injection may
also cause vasospasm.
The most serious adverse reaction to mineral oil is lipoid
pneumonia caused by aspiration of the oil.Mineral oil can
enter the bronchial tree without eliciting the cough reflex.With
the reduction in the use of mineral oil in nasal formulations, the
incidence of lipoid pneumonia has been greatly reduced. However,
lipoid pneumonia has also been associated with the use of mineral
oil-containing cosmetics and ophthalmic preparations.It is
recommended that products containing mineral oil not be used in
very young children, the elderly, or persons with debilitating
illnesses.
Given its widespread use in many topical products, mineral oil
has been associated with few instances of allergic reactions.
The WHO has not specified an acceptable daily intake of
mineral oil given the low concentration consumed in foods.
LD50 (mouse, oral): 22 g/kg
Potential Exposure
Tumorigen,Human Data; Primary Irritant. Mineral oil is used in cosmetics, pharmaceutical bases, food, and fiber production; ascarriers and bases; as a lubricating oil; and as a solvent forinks in the printing industry. Oil mist would be encounteredin quenching of hot metal parts and in metal machiningoperations.
First aid
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility
storage
Mineral oil undergoes oxidation when exposed to heat and light.
Oxidation begins with the formation of peroxides, exhibiting an
‘induction period’. Under ordinary conditions, the induction period
may take months or years. However, once a trace of peroxide is
formed, further oxidation is autocatalytic and proceeds very
rapidly. Oxidation results in the formation of aldehydes and
organic acids, which impart taste and odor. Stabilizers may be added to retard oxidation; butylated hydroxyanisole, butylated
hydroxytoluene, and alpha tocopherol are the most commonly used
antioxidants.
Mineral oil may be sterilized by dry heat.
Mineral oil should be stored in an airtight container, protected
from light, in a cool, dry place.
Purification Methods
Treat the oil with fuming H2SO4 (care), then wash it with water and dilute aqueous NaOH, then percolate it through activated silica gel. Paraffin Wax. Melt the wax in the presence of NaOH, wash it with water until all of the base had been removed. The paraffin is allowed to solidify after each wash. Finally, 5g of paraffin is melted by heating it on a water-bath, then shaken for 20-30minutes with 100mL of boiling water and and dry the melt under vacuum.
Incompatibilities
Incompatible with strong oxidizing agents.
Regulatory Status
GRAS listed. Accepted in the UK for use in certain food applications. Included in the FDA Inactive Ingredients Database (dental preparations; IV injections; ophthalmic preparations; oral capsules and tablets; otic, topical, transdermal, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Paraffin, liquid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2541 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from Paraffin, liquid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-27 | PARAFFIN
8012-95-1
|
US $10.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-05 | PARAFFIN
8012-95-1
|
US $0.00-0.00 / KG | 1g | 99% | 20tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-10-30 | PARAFFIN
8012-95-1
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd |
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