ChemicalBook >> CAS DataBase List >>N-palMitoyl-1-deoxysphinganine (M18:0/16:0)
N-palMitoyl-1-deoxysphinganine (M18:0/16:0)
- CAS No.
- 378755-69-2
- Chemical Name:
- N-palMitoyl-1-deoxysphinganine (M18:0/16:0)
- Synonyms
- N-C16-deoxysphinganine;N-palMitoyl-1-deoxysphinganine (M18:0/16:0);Hexadecanamide, N-[(1S,2R)-2-hydroxy-1-methylheptadecyl]-;N-PALMITOYL-1-DEOXYSPHINGANINE (M18:0/16:0);N-C16-DEOXYSPHINGANINE
- CBNumber:
- CB52720716
- Molecular Formula:
- C34H69NO2
- Molecular Weight:
- 523.92
- MDL Number:
- MFCD22416666
- MOL File:
- 378755-69-2.mol
N-palMitoyl-1-deoxysphinganine (M18:0/16:0) price More Price(1)
N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Chemical Properties,Uses,Production
General Description
N-C16-deoxysphinganine Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The N-acyl group can be 16, 20 and 24 carbon chain. N-acylsphinganines (dihydroceramides) are synthesized by the acylation of sphingoid bases in the presence of ceramide synthases (CerS).
Biochem/physiol Actions
N-acylsphinganines (dihydroceramides) levels are lower during ceramide synthase inhibition. They are intermediates of ceramide and dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.
N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Preparation Products And Raw materials
Raw materials
Preparation Products
N-palMitoyl-1-deoxysphinganine (M18:0/16:0) Suppliers
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N-palMitoyl-1-deoxysphinganine (M18:0/16:0)
N-C16-deoxysphinganine
N-PALMITOYL-1-DEOXYSPHINGANINE (M18:0/16:0);N-C16-DEOXYSPHINGANINE
Hexadecanamide, N-[(1S,2R)-2-hydroxy-1-methylheptadecyl]-
378755-69-2
C34H69NO2