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ML-180

ML-180 structure

CAS No.: 863588-32-3

Chemical Name:: ML-180

Synonyms: SR1848;ML-180;ML-180 (SR1848);SR1848 >=98% (HPLC);6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2，4-dione;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-

CBNumber:: CB53152684

Molecular Formula:: C20H25ClN4O2

Molecular Weight:: 388.89

MDL Number:: MFCD05894342

MOL File:: 863588-32-3.mol

MSDS File:: SDS

Last updated:2024-11-09 21:40:10

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ML-180 Properties

Density	1.312±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 10 mg/ml
form	A crystalline solid
pka	9.37±0.40(Predicted)
color	Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P330-P501

NFPA 704

	0
2		0

ML-180 price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	15181	ML-180 ≥98%	863588-32-3	1mg	$37	2024-03-01	Buy
Cayman Chemical	15181	ML-180 ≥98%	863588-32-3	5mg	$108	2024-03-01	Buy
Cayman Chemical	15181	ML-180 ≥98%	863588-32-3	10mg	$161	2024-03-01	Buy
Cayman Chemical	15181	ML-180 ≥98%	863588-32-3	25mg	$345	2024-03-01	Buy
AK Scientific	SYN5289	ML180	863588-32-3	10mg	$160	2021-12-16	Buy

Product number	Packaging	Price	Buy
15181	1mg	$37	Buy
15181	5mg	$108	Buy
15181	10mg	$161	Buy
15181	25mg	$345	Buy
SYN5289	10mg	$160	Buy

ML-180 Chemical Properties,Uses,Production

Description

ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC₅₀ = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC₅₀ = 2.05 μM).

Definition

ChEBI: 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione is a member of piperazines.

ML-180 Preparation Products And Raw materials

Raw materials

Preparation Products

ML-180 Suppliers

Global( 52)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32951	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32077	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30241	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38468	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973	sales@jamxmpharmatech.com	China	1106	58
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4428	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58
Guangzhou Isun Pharmaceutical Co., Ltd	55

View Lastest Price from ML-180 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-09	ML-180 863588-32-3	US $30.00-70.00 / mg		99.74%	10g	TargetMol Chemicals Inc.
	2024-11-09	ML-180 863588-32-3	US $30.00-70.00 / mg		99.74%	10g	TargetMol Chemicals Inc.

ML-180
863588-32-3
US $30.00-70.00 / mg
99.74%
TargetMol Chemicals Inc.

ML-180
863588-32-3
US $30.00-70.00 / mg
99.74%
TargetMol Chemicals Inc.

ML-180 Spectrum

ML-180(863588-32-3)¹HNMR

863588-32-3(ML-180)Related Search:

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ML188 ML418 [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone ML213 N-(3,4-difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine

ML-327 PTP1B-IN-2 ML264

1of4

ML-180 SR1848 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione 2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl- 6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione SR1848 >=98% (HPLC) ML-180 (SR1848) 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ML-180,steroidogenic,SR-1848,Inhibitor,ML180,Orphan,factor-1,LRH-1,cancers,nuclear,NR5A2,NR5A1,ML 180,inhibit,homolog,liver,SR 1848,receptor,SF-1 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2，4-dione 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione 863588-32-3