ChemicalBook >> CAS DataBase List >>Sp-Cyclic AMPS (sodium salt)

Sp-Cyclic AMPS (sodium salt)

CAS No.
142439-95-0
Chemical Name:
Sp-Cyclic AMPS (sodium salt)
Synonyms
YTUKZYORDGLGPR-BIQAKYJPSA-M;Sp-Cyclic AMPS (sodium salt)
CBNumber:
CB53152745
Molecular Formula:
C10H13N5NaO5PS
Molecular Weight:
369.27
MDL Number:
MFCD03703496
MOL File:
142439-95-0.mol
Last updated:2023-05-21 10:59:17

Sp-Cyclic AMPS (sodium salt) Properties

storage temp. Store at -20°C
solubility ≤25mg/ml in H2O
form crystalline solid

Sp-Cyclic AMPS (sodium salt) price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14983 Sp-Cyclic AMPS (sodium salt) ≥98% 142439-95-0 1mg $68 2024-03-01 Buy
Cayman Chemical 14983 Sp-Cyclic AMPS (sodium salt) ≥98% 142439-95-0 5mg $302 2024-03-01 Buy
ApexBio Technology C4942 Sp-CyclicAMPS(sodiumsalt) 142439-95-0 5mg $344 2021-12-16 Buy
ChemScene CS-0107086 Sp-cAMPS(sodiumsalt) 142439-95-0 5mg $500 2021-12-16 Buy
ChemScene CS-0107086 Sp-cAMPS(sodiumsalt) 142439-95-0 10mg $850 2021-12-16 Buy
Product number Packaging Price Buy
14983 1mg $68 Buy
14983 5mg $302 Buy
C4942 5mg $344 Buy
CS-0107086 5mg $500 Buy
CS-0107086 10mg $850 Buy

Sp-Cyclic AMPS (sodium salt) Chemical Properties,Uses,Production

Description

Several cyclic nucleotide phosphodiesterases (PDE2, -5, -6, -10, and -11) contain a tandem of GAF domains in their N-terminal regulatory region that are thought to mediate cAMP- or cGMP-induced stimulation of adenylyl and guanylyl cyclases. Sp-cyclic AMPS (Sp-cAMPS) is a derivative of cAMP that binds the PDE10 GAF domain (EC50 = 40 μM). It has been used to study GAF-mediated stimulation of PDE10.

References

[1] dostmann w r, taylor s s, genieser h g, et al. probing the cyclic nucleotide binding sites of camp-dependent protein kinases i and ii with analogs of adenosine 3', 5'-cyclic phosphorothioates[j]. journal of biological chemistry, 1990, 265(18): 10484-10491.
[2] hanks s k, quinn a m, hunter t. the protein kinase family: conserved features and deduced phylogeny of the catalytic domains[j]. science, 1988, 241(4861): 42-52.
[3] spicuzza l, belvisi m g, birrell m a, et al. evidence that the anti‐spasmogenic effect of the β‐adrenoceptor agonist, isoprenaline, on guinea‐pig trachealis is not mediated by cyclic amp‐dependent protein kinase[j]. british journal of pharmacology, 2001, 133(8): 1201-1212.

Sp-Cyclic AMPS (sodium salt) Preparation Products And Raw materials

Raw materials

Preparation Products

Sp-Cyclic AMPS (sodium salt) Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762 sales@hasunny.com China 2380 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9154 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
Sp-Cyclic AMPS (sodium salt) YTUKZYORDGLGPR-BIQAKYJPSA-M 142439-95-0