ChemicalBook >> CAS DataBase List >>E3 ligase Ligand-Linker Conjugates 5
E3 ligase Ligand-Linker Conjugates 5
- CAS No.
- 2097971-11-2
- Chemical Name:
- E3 ligase Ligand-Linker Conjugates 5
- Synonyms
- VH032-PEG3-NH2 hydrochloride;(S,R,S)-AHPC-PEG3-NH2 hydrochloride;E3 ligase Ligand-Linker Conjugates 5;(S,R,S)-AHPC-PEG3-NH2 hydrochloride >=95%;VHL Ligand-Linker Conjugates 1 hydrochloride;(S,R,S)-AHPC-PEG3-NH2 hydrochloride（E3 ligase Ligand-Linker Conjugates 5）;(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2R,4S)-1-((R)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride;(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride;(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
- CBNumber:
- CB53386472
- Molecular Formula:
- C30H46ClN5O7S
- Molecular Weight:
- 656.24
- MDL Number:
- MFCD31656714
- MOL File:
- 2097971-11-2.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:11
E3 ligase Ligand-Linker Conjugates 5 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 901511 | (S,R,S)-AHPC-PEG3-NH2 hydrochloride ≥95% | 2097971-11-2 | 50mg | $326 | 2024-03-01 | Buy |
| Iris Biotech GmbH | PTC1330 | (S,R,S)-AHPC-PEG3-NH2 hydrochloride | 2097971-11-2 | 50mg | $499.5 | 2021-12-16 | Buy |
| DC Chemicals | 027599 | (S,R,S)-AHPC-PEG3-NH2hydrochloride（E3ligaseLigand-LinkerConjugates5） | 2097971-11-2 | 001 | $500 | 2021-12-16 | Buy |
| DC Chemicals | 027599 | (S,R,S)-AHPC-PEG3-NH2hydrochloride（E3ligaseLigand-LinkerConjugates5） | 2097971-11-2 | 002 | $850 | 2021-12-16 | Buy |
| DC Chemicals | 027599 | (S,R,S)-AHPC-PEG3-NH2hydrochloride（E3ligaseLigand-LinkerConjugates5） | 2097971-11-2 | 003 | $1700 | 2021-12-16 | Buy |
E3 ligase Ligand-Linker Conjugates 5 Chemical Properties,Uses,Production
Uses
Protein degrader builiding block (S,R,S)-AHPC-PEG3-NH2 (HCl salt) enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with pendant amine for reactivity with a carboxyl group on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant amine, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
E3 ligase Ligand-Linker Conjugates 5 Preparation Products And Raw materials
Raw materials
Preparation Products
E3 ligase Ligand-Linker Conjugates 5 Suppliers
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6930 | 58 |
| Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 | sales@tihondan.com | China | 3725 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ChemShuttle, Inc. | 0510-83588313-802 18800520310; | sales@chemshuttle.com | China | 3000 | 62 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25014 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9887 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4824 | 58 |
View Lastest Price from E3 ligase Ligand-Linker Conjugates 5 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | (S,R,S)-AHPC-PEG3-NH2 hydrochloride
2097971-11-2
|
US $0.00 / mg | 250mg | >98.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- (S,R,S)-AHPC-PEG3-NH2 hydrochloride
2097971-11-2
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
E3 ligase Ligand-Linker Conjugates 5
VH032-PEG3-NH2 hydrochloride
VHL Ligand-Linker Conjugates 1 hydrochloride
(S,R,S)-AHPC-PEG3-NH2 hydrochloride >=95%
(S,R,S)-AHPC-PEG3-NH2 hydrochloride（E3 ligase Ligand-Linker Conjugates 5）
(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
(2R,4S)-1-((R)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
2097971-11-2