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Prednicarbate

Prednicarbate structure

CAS No.: 73771-04-7

Chemical Name:: Prednicarbate

Synonyms: Regemt;Regenit;HOE-777;Dermatop;Prednitop;S-77-0777;PREDNICARBATE;UNII-V901LV1K7D;Prednicarbate CRS;Prednicarbate, >=98%

CBNumber:: CB5342987

Molecular Formula:: C27H36O8

Molecular Weight:: 488.57

MDL Number:: MFCD00867445

MOL File:: 73771-04-7.mol

Last updated:2023-09-04 15:51:00

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Prednicarbate Properties

Melting point	110-112°; mp 183°
alpha	D20 +63° (c = 0.1 in ethanol)
Boiling point	640.7±55.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), sparingly soluble in propylene glycol. It shows polymorphism (5.9).
pka	14.05±0.70(Predicted)
color	White to Off-White
FDA UNII	V901LV1K7D
ATC code	D07AC18

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS08

Signal word

Danger

Hazard statements

H360D

Precautionary statements

P201-P280-P308+P313

HS Code

2937290000

NFPA 704

	0
2		0

Prednicarbate price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0002231	Prednicarbate for peak identification CRS, European Pharmacopoeia (EP) Reference Standard	73771-04-7	Y0002231	$161	2024-03-01	Buy
Sigma-Aldrich	PHR3101	Prednicarbate pharmaceutical secondary standard, certified reference material	73771-04-7	500MG	$186	2024-03-01	Buy
Sigma-Aldrich	P2698000	Prednicarbate European Pharmacopoeia (EP) Reference Standard	73771-04-7	p2698000	$153	2024-03-01	Buy
Sigma-Aldrich	1554909	Prednicarbate	73771-04-7	200mg	$358	2024-03-01	Buy
Cayman Chemical	23668	Prednicarbate ≥98%	73771-04-7	5mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
Y0002231	Y0002231	$161	Buy
PHR3101	500MG	$186	Buy
P2698000	p2698000	$153	Buy
1554909	200mg	$358	Buy
23668	5mg	$32	Buy

Prednicarbate Chemical Properties,Uses,Production

Description

Prednicarbate is a potent topical antiinflammatory agent with minimal systemic effects. It is useful in the treatment of cutaneous inflammatory disorders such as eczema and psoriasis.

Description

Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone . It has anti-inflammatory activity comparable to that of desoximetasone in various murine models when administered topically but lacks activity when administered subcutaneously. Topical administration of prednicarbate (2 drops of a 0.1% solution per day) induces wound healing in hairless mice. Formulations containing prednicarbate have been used to treat chronic hand eczema.

Chemical Properties

White or almost white, crystalline powder.

Originator

Hoechst AG (W. Germany)

Uses

Topical anti-inflammatory agent. Glucocorticoid.
Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

Definition

ChEBI: Prednicarbate is a corticosteroid hormone.

Indications

Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

brand name

Dermatop (Sanofi Aventis).

General Description

Prednicarbate, 17-[(ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, is a prednisolone derivative with a C21 propionateester and a C17 ethyl carbonate group. It is availablefor use only in a 0.1% topical cream. Prednicarbate is amedium-potency GC.

Prednicarbate Preparation Products And Raw materials

Raw materials

Silica gel Acetic anhydride Propionyl chloride Prednisolone Tetraethyl orthocarbonate

PARA TOLUENE Sodium bicarbonate Anhydrous pyridine

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Preparation Products

Prednicarbate Suppliers

Global( 111)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29885	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32072	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15356	58
Wuhan Fortuna Chemical Co., Ltd	+86-027-59207850	info@fortunachem.com	China	5985	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Hebei Fengjia New Material Co., Ltd	+86-0311-87836622 +86-17333973358	sales06@hbduling.cn	China	8054	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58

Supplier	Advantage
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
AFINE CHEMICALS LIMITED	58
Wuhan Fortuna Chemical Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hebei Fengjia New Material Co., Ltd	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58

View Lastest Price from Prednicarbate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-04	Prednicarbate 73771-04-7	US $0.00 / Kg/Bag	1KG	97%-102%; EPV	50kgs	WUHAN FORTUNA CHEMICAL CO., LTD
	2019-07-10	Prednicarbate 73771-04-7	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

Prednicarbate
73771-04-7
US $0.00 / Kg/Bag
97%-102%; EPV
WUHAN FORTUNA CHEMICAL CO., LTD

Prednicarbate
73771-04-7
US $7.00 / KG
99%
Career Henan Chemical Co

Prednicarbate Spectrum

Prednicarbate(73771-04-7)¹HNMR

73771-04-7(Prednicarbate)Related Search:

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Clindamycin 4-Phosphate Ambroxol hydrochloride N-Deformyl-N-pivaloyl Orlistat 10-Propargyl-10-deazaaminopterin

Cilastatin Esmolol Impurity 2 HCl (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone AMbroxol EP IMpurity D GATIFLOXACIN RELATED COMPOUND A

Eflone Prednisolone-21-acetate Prednicarbate Prednicarbate Related Compound A Prednicarbate Related Compound C

Prednicarbate Related Compound B Prednisolone prednisolone 17-ethylcarbonate

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PREDNICARBATE 11β，17，21-Trihydroxypregna-1，4-diene-3，20-dione 17-(ethylcarbonate)-21-propionate [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate Dermatop HOE-777 Prednitop Regemt S-77-0777 Prednisolone 17-(ethyl carbonate) 21-propionate Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11b)- Regenit 17-[(Ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione 17-[(Ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione Prednicarbate (200 mg) (11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione Prednicarbate, >=98% Prednicarbate for system suitability A Prednicarbate for system suitability Prednicarbate CRS Prednicarbate for system suitability A CRS Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11β)- 2-((8S,9S,10R,11S,13S,14S,17R)-17-((ethoxycarbonyl)oxy)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl propionate Prednicarbate (1554909) Dermatop E emollient UNII-V901LV1K7D C16286450 Prednicarbate 73771-04-7 C27H36O8 Intermediates & Fine Chemicals Pharmaceuticals Steroids