1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
- CAS No.
- 288862-73-7
- Chemical Name:
- 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
- Synonyms
- CAY10435;1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE;1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-;1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
- CBNumber:
- CB5423194
- Molecular Formula:
- C18H26N2O2
- Molecular Weight:
- 302.41
- MDL Number:
- MFCD08062146
- MOL File:
- 288862-73-7.mol
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 10005102 | CAY10435 ≥98% | 288862-73-7 | 500μg | $53 | 2023-06-20 | Buy |
Cayman Chemical | 10005102 | CAY10435 ≥98% | 288862-73-7 | 1mg | $99 | 2023-06-20 | Buy |
Cayman Chemical | 10005102 | CAY10435 ≥98% | 288862-73-7 | 5mg | $411 | 2023-06-20 | Buy |
Cayman Chemical | 10005102 | CAY10435 ≥98% | 288862-73-7 | 10mg | $718 | 2023-06-20 | Buy |
AK Scientific | 1312AH | 1-Oxazolo[4,5-b]pyridin-2-yl-1-dodecanone | 288862-73-7 | 5mg | $564 | 2021-12-16 | Buy |
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Chemical Properties,Uses,Production
Description
Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.57 nM. Using a proteonomics approach, CAY10435 was screened against the serine hydrolase family of enzymes, of which FAAH is a member. In this assay, CAY10435 exhibited IC50 values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Knowledge of the specificity of CAY10435 obtained from this experiment should allow for more accurate interpretation of results using the inhibitor in complex environments such as whole cells or animals.
Definition
ChEBI: CAY10435 is an oxazolopyridine.
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Preparation Products And Raw materials
Raw materials
Preparation Products
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 15162312715 | sales@szzxbio.com | China | 3002 | 58 |
Supplier | Advantage |
---|---|
Shanghai Hongye Biotechnology Co. Ltd | 58 |
Suzhou Zhixin Biotechnology Co., Ltd. | 58 |