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Boc-D-Ser(Bzl)-OH

Boc-D-Ser(Bzl)-OH Structure
Boc-D-Ser(Bzl)-OH structure
CAS No.
47173-80-8
Chemical Name:
Boc-D-Ser(Bzl)-OH
Synonyms
O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE;BOC-SER(BZL)-OH;BOC-SER(BZL);BOC-D-SER(BZL);BOC-O-BENZYL-L-SERINE;(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid;(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;BOC-L-SER(BZL);(2R)-3-(benzylox;BOC-D-SER(BZL)-OH
CBNumber:
CB5438415
Molecular Formula:
C15H21NO5
Molecular Weight:
295.33
MDL Number:
MFCD00038248
MOL File:
47173-80-8.mol
MSDS File:
SDS
Last updated:2024-05-16 10:38:43
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Boc-D-Ser(Bzl)-OH Properties

Melting point 58-60 °C(lit.)
alpha -19 º (c=2 80% alcohol)
Boiling point 437.02°C (rough estimate)
Density 1.1454 (rough estimate)
refractive index -20 ° (C=2, 80% EtOH)
storage temp. Sealed in dry,Room Temperature
solubility almost transparency in Methanol
pka 3.53±0.10(Predicted)
form Powder
color White
BRN 2665080
InChI InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1
InChIKey DMBKPDOAQVGTST-GFCCVEGCSA-N
SMILES C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference 47173-80-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HS Code  2924 29 70
HazardClass  IRRITANT
NFPA 704
1
0 0

Boc-D-Ser(Bzl)-OH price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.53111 Boc-D-Ser(Bzl)-OH Novabiochem? 47173-80-8 25g $196 2024-03-01 Buy
Sigma-Aldrich 15078 Boc-D-Ser(Bzl)-OH ≥98.0% (HPLC) 47173-80-8 5g $413 2024-03-01 Buy
TCI Chemical B1863 O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T) 47173-80-8 1g $66 2024-03-01 Buy
TCI Chemical B1863 O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T) 47173-80-8 5g $212 2024-03-01 Buy
Alfa Aesar B22666 N-Boc-O-benzyl-D-serine, 99% 47173-80-8 5g $180 2021-12-16 Buy
Product number Packaging Price Buy
8.53111 25g $196 Buy
15078 5g $413 Buy
B1863 1g $66 Buy
B1863 5g $212 Buy
B22666 5g $180 Buy

Boc-D-Ser(Bzl)-OH Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

N-BOC-O-Benzyl-D-serine, is an amino acid derivative used in chemical synthesis and peptide chemistry.is used in preparation of substituted naphthyl thiadiazolidinones as protein tyrosine phosphatase degraders for treating cancer and metabolic diseases.

Biological Activity

Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.

Synthesis

N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.

Boc-D-Ser(Bzl)-OH synthesis

24424-99-5
47173-80-8
Synthesis of Boc-D-Ser(Bzl)-OH from Di-tert-butyl dicarbonate

Boc-D-Ser(Bzl)-OH Preparation Products And Raw materials

Raw materials

O-Benzyl-D-serine Di-tert-butyl dicarbonate Benzyl bromide

Preparation Products

MK-677 Carbamic acid, N-[(1R)-1-formyl-2-(phenylmethoxy)ethyl]-, 1,1-dimethylethyl ester Boc-N-Me-D-Ser(Bzl)-OH

Boc-D-Ser(Bzl)-OH Suppliers

Global( 272)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8617390183901 daisy@enlaibio.com China 1106 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3002 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18751 58
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
AB PharmaTech,LLC 		323-480-4688 sales@acrospharmatech.com United States 989 55
GenicBio Limited 		+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Supplier Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Shanghai Time Chemicals CO., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
AB PharmaTech,LLC 		55
GenicBio Limited 		58
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58

View Lastest Price from Boc-D-Ser(Bzl)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-D-Ser(Bzl)-OH pictures 2024-12-23 Boc-D-Ser(Bzl)-OH
47173-80-8
 US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
Boc-D-Ser(Bzl)-OH pictures 2024-12-23 Boc-D-Ser(Bzl)-OH
47173-80-8
 US $32.00 / kg 1kg 99% 5000kg/week Hebei Zhuanglai Chemical Trading Co.,Ltd
Boc-D-Ser(Bzl)-OH pictures 2024-12-13 Boc-D-Ser(Bzl)-OH
47173-80-8
 US $0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
  • Boc-D-Ser(Bzl)-OH pictures
  • Boc-D-Ser(Bzl)-OH
    47173-80-8
  • US $32.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd

Boc-D-Ser(Bzl)-OH Spectrum

N-Boc-O-Benzyl-D-serine(47173-80-8)MSN-Boc-O-Benzyl-D-serine(47173-80-8)1HNMRN-Boc-O-Benzyl-D-serine(47173-80-8)13CNMRN-Boc-O-Benzyl-D-serine(47173-80-8)IR1N-Boc-O-Benzyl-D-serine(47173-80-8)IR2

47173-80-8(Boc-D-Ser(Bzl)-OH)Related Search:

Benzyl chloride D-Serine Benzyl benzoate L-Homoserine tert-Butanol
Boc-Ser(tBu)-OH N-Carbobenzyloxyglycine Benzyl bromide DL-Serine Benzyltriethylammonium chloride
Benzyl alcohol L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE Boc-Aib-OH D-Cycloserine Benzyltrimethylammonium chloride
Boc-O-benzyl-L-serine, N-(tert-Butoxycarbonyl)-O-benzyl-L-serine,N-BOC-O-Benzyl-L-serine,N-T-BOC-O-BENZYL-L-SERINE CRYSTALLINE BOC-GLY-LEU-OH Boc-His(Trt)-OH

1of4

(2R)-2-(tert-butoxycarbonylamino)-3-(phenylmethoxy)propanoic acid (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethoxy)propanoic acid (2R)-2-[(tert-butoxy-oxomethyl)amino]-3-(phenylmethoxy)propanoic acid (2R)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propionic acid L-Serine, N-((1,1-dimethylethoxy)carbonyl)-O-(phenylmethyl)- Boc-D-Ser(Bzl)-OH, >=98% BOC-D-SERINE(BZL)-OH BOC-D-SER(BZL)-OH BOC-SERINE(BZL)-OH BOC-(S)-2-AMINO-3-BENZYLOXYPROPIONIC ACID BOC-O-BENZYL-D-SERINE BOC-(R)-2-AMINO-3-BENZYLOXYPROPIONIC ACID BOC-L-SER(BZL)-OH BOC-L-SERINE (BZL) BOC-L-SER(BZL) O-Benzyl-N-(tert-butoxycarbonyl)-D-serine Boc-O-benzyl-D-serine≥ 99.5% (HPLC) NALPHA-tert-Butoxycarbonyl-O-benzyl-D-serine N-BOC-O-Benzyl-D-serine,98% N-t-BOC-O-Benzyl-D-serine N-Boc-O-Benzyl-D-ser Boc-D-Ser(Bzl)-OH Boc-O-benzyl-D-Serine N-Boc-O-benzyl-D-serine Boc-D-Ser(Bzl)-OH T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE T-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE TBOC-L-SERINE (BZL) N-ALPHA-T-BOC-O-BENZYL-L-SERINE N-ALPHA-T-BOC-O-BENZYL-D-SERINE N-ALPHA-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE N-ALPHA-TERT-BOC-O-BENZYL-L-SERINE N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE N-BOC-O-BENZYL-D-SERINE Boc-DL-Ser(Bzl)-OH N-TERT-BUTOXYCARBONYL-O-BENZYL-D-SERINE N-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE (Tert-Butoxy)Carbonyl D-Ser(Bzl)-OH (2R)-3-(benzylox O-Benzyl-N-Boc-D-serine O-Benzyl-N-(tert-butoxycarbonyl)-D-serine > D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- BOC-SER(BZL)-OH BOC-SER(BZL) BOC-O-BENZYL-L-SERINE (R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE BOC-D-SER(BZL) (2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid N-[(1,1-Dimethylethoxy)carbonyl]-O-(phenylmethyl)-D-serine (s)-(+)-3-Benzyloxy-2-(Boc-amino)-1-propanol BOC-D-Ser(OBZL)-OH 47173-80-8 47473-80-8 47173-80-6 C15H20NO5 Specialty Synthesis Peptide Synthesis