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2'-C-Methylcytidine

2'-C-Methylcytidine Structure
2'-C-Methylcytidine structure
CAS No.
20724-73-6
Chemical Name:
2'-C-Methylcytidine
Synonyms
NM-107;CS-2055;-C-Methylcytidine;2''-METHYLCYTIDINE;2'-C-METHYLCYTIDINE;2’-C-Methyl cytidine;2'-CMethyl-D-cytidine;2’-β-C-Methylcytidine;Cytidine, 2'-C-methyl-;2’-b-C-Methyl cytidine
CBNumber:
CB5732016
Molecular Formula:
C10H15N3O5
Molecular Weight:
257.24
MDL Number:
MFCD02682947
MOL File:
20724-73-6.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33
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2'-C-Methylcytidine Properties

Melting point 243-245°C
Boiling point 523.9±60.0 °C(Predicted)
Density 1.72±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: >20mg/mL
pka 13.53±0.70(Predicted)
form powder
color white to off-white
InChIKey PPUDLEUZKVJXSZ-VPCXQMTMSA-N
FDA UNII 27FS20C1D8

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

2'-C-Methylcytidine price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M4949 2’-C-Methylcytidine ≥95% (HPLC), powder 20724-73-6 5mg $97.9 2024-03-01 Buy
Sigma-Aldrich M4949 2’-C-Methylcytidine ≥95% (HPLC), powder 20724-73-6 25mg $388 2024-03-01 Buy
Cayman Chemical 22887 2'-C-Methylcytidine ≥98% 20724-73-6 5mg $86 2024-03-01 Buy
Cayman Chemical 22887 2'-C-Methylcytidine ≥98% 20724-73-6 10mg $161 2024-03-01 Buy
Cayman Chemical 22887 2'-C-Methylcytidine ≥98% 20724-73-6 25mg $336 2024-03-01 Buy
Product number Packaging Price Buy
M4949 5mg $97.9 Buy
M4949 25mg $388 Buy
22887 5mg $86 Buy
22887 10mg $161 Buy
22887 25mg $336 Buy

2'-C-Methylcytidine Chemical Properties,Uses,Production

Description

2''-C-Methylcytidine (2CMC) is a ribonucleoside with broad-spectrum antiviral activity. It reduces the number of viral plaques in BHK-21 cells infected with dengue type 2, reovirus type 1, West Nile, and yellow fever RNA viruses with EC50 values of 95, 26, 80, and 75 μM, respectively. 2CMC inhibits hepatitis C virus (HCV) replication (EC50 = 2.2 μM in a replicon assay) and protects MDBK cells from infection with bovine virus diarrhea virus (BVDV; EC50 = 2.2 μM) and human coronavirus (HCoV; EC50 = 90 μM). It also reduces infectious virus yield in BHK-21 cells infected with foot-and-mouth disease virus (FMDV; EC50 = 6.4 μM) and swine vesicular disease virus (SVDV; EC50 = 45.2 μM). In vivo, 2CMC reduces viral shedding to undetectable levels in a mouse model of persistent norovirus infection.

Chemical Properties

White to Off-White Powder

Uses

2’-C-Methyl Cytidine (cas# 20724-73-6) is a compound useful in organic synthesis.

Biochem/physiol Actions

2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.

2'-C-Methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

2'-C-Methylcytidine Suppliers

Global( 116)Suppliers
Supplier Tel Email Country ProdList Advantage
NewCan Biotech Limited
+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9980 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Nanjing Baifuli Technology Co., Ltd. 		+86-15335185688 sales@unisyn.cn CHINA 332 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Supplier Advantage
NewCan Biotech Limited
58
career henan chemical co 		58
Nanjing Baifuli Technology Co., Ltd. 		58
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from 2'-C-Methylcytidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NM107 pictures 2024-11-19 NM107
20724-73-6
 US $35.00-77.00 / mg 98% 10g TargetMol Chemicals Inc.
2'-C-methylCytidine pictures 2024-06-03 2'-C-methylCytidine
20724-73-6
 US $0.00-0.00 / g 1g 98% 100g NewCan Biotech Limited
2'-C-Methylcytidine pictures 2019-08-06 2'-C-Methylcytidine
20724-73-6
 US $5.00 / KG 1KG 99% 1ton Career Henan Chemical Co
  • NM107 pictures
  • NM107
    20724-73-6
  • US $35.00-77.00 / mg
  • 98%
  • TargetMol Chemicals Inc.

20724-73-6(2'-C-Methylcytidine)Related Search:

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2'-C-Methylcytidine

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2'-C-METHYLCYTIDINE 2'-CMethyl-D-cytidine 2''-METHYLCYTIDINE 1-(2-C-Methyl-β-D-ribofuranosyl)cytosine NM-107 2'-C-Methyl-1-β-D-ribofuranosylcytosine -C-Methylcytidine 2'-C-METHYLCYTIDINE;NM-107;VALOPICITABINE CS-2055 4-AMINO-1-[3,4-DIHYDROXY-5-(HYDROXYMETHYL)-3-METHYLOXOLAN-2-YL]PYRIMIDIN-2-ONE Cytidine, 2'-C-methyl- 2’-C-Methyl cytidine, 2’-C-Methyl-1-β-D-ribofuranosyl cytosine 2’-β-C-Methylcytidine 2'-C-Methylcytidine USP/EP/BP 4-Amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 2’-b-C-Methyl cytidine NM107, HCV drug 2’-b-C-Methyl cytidine 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one NM 107,inhibit,Inhibitor,HCV,Hepatitis C virus,NM107 2’-C-Methyl cytidine 2’-b-C-Methyl cytidine 20724-73-6 C10H15N3O5 Bases & Related Reagents Nucleotides