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8-AZAGUANINE

8-AZAGUANINE structure

CAS No.: 134-58-7

Chemical Name:: 8-AZAGUANINE

Synonyms: Azaguanine;8ag;AZG;8 AG;Azan;B-28;8-AzaG;SF-337;sk1150;NSC-749

CBNumber:: CB5752825

Molecular Formula:: C4H4N6O

Molecular Weight:: 152.11

MDL Number:: MFCD00056937

MOL File:: 134-58-7.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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8-AZAGUANINE Properties

Melting point	>300 °C(lit.)
Boiling point	274.55°C (rough estimate)
Density	1.5579 (rough estimate)
refractive index	2.3000 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Slightly)
form	lyophilized powder
pka	6.75±0.20(Predicted)
color	White to yellow
Merck	896
InChIKey	LPXQRXLUHJKZIE-UHFFFAOYSA-N
CAS DataBase Reference	134-58-7(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	Q150359I72
NIST Chemistry Reference	8-Azaguanine(134-58-7)
EPA Substance Registry System	8-Azaguanine (134-58-7)
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312+P330-P501
Hazard Codes	Xn
Risk Statements	22
Safety Statements	22-24/25
WGK Germany	3
RTECS	XZ6157000
F	10-23
HS Code	29335990
Toxicity	LD50 oral in mouse: 1500mg/kg

8-AZAGUANINE price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A806065	8-Azaguanine	134-58-7	5g	$195	2021-12-16	Buy
Biosynth Carbosynth	FA07970	8-Azaguanine	134-58-7	50g	$580	2021-12-16	Buy
Matrix Scientific	093129	5-Amino-1H-[1,2,3]triazolo-[4,5-d]pyrimidin-7(6H)-one 95+%	134-58-7	5g	$908	2021-12-16	Buy
AK Scientific	J93879	8-Azaguanine	134-58-7	1g	$30	2021-12-16	Buy
AK Scientific	J93879	8-Azaguanine	134-58-7	5g	$90	2021-12-16	Buy

Product number	Packaging	Price	Buy
A806065	5g	$195	Buy
FA07970	50g	$580	Buy
093129	5g	$908	Buy
J93879	1g	$30	Buy
J93879	5g	$90	Buy

8-AZAGUANINE Chemical Properties,Uses,Production

Chemical Properties

yellow powder

Uses

8-Azaguanine, is a purine analogue which shows antineoplastic activity.

Uses

Antineoplastic;Purine antimetabolite

Definition

ChEBI: A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.

Hazard

Mitotoic poison.

Biological Activity

8-Azaguanine is a triazole-antimetabolite th at displays varies pharmacological effects including anticancer, antiviral and antifungal. It is easily incorporated into ribonucleic acids including rRNA and tRNA. 8-Azaguanine appears to alter mRNA splicing in SF3B1 mutant cells. 8-Azaguanine novel immunomodulatory drug (IMiD) th at significantly increases the cytotoxicity of NK cells.

Purification Methods

Dissolve it in hot M NH4OH, filter, and cool. Recrystallise it, and wash it with water, then dry it in a vacuum. [Beilstein 26 III/IV 4171.]

8-AZAGUANINE Preparation Products And Raw materials

Raw materials

Nitro Sodium dithionite Congo Red 2,4-Diamino-6-hydroxypyrimidine ,98% Amino

Preparation Products

8-AZAGUANINE Suppliers

Global( 204)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	7906	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58

Supplier	Advantage
Shanghai UCHEM Inc.	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58

View Lastest Price from 8-AZAGUANINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-02-08	8-Azaguanine 134-58-7	US $7.00-161.00 / g	1g	0.97	10kg	Shanghai UCHEM Inc.
2024-11-19	8-Azaguanine 134-58-7	US $30.00-55.00 / mg		99.89%	10g	TargetMol Chemicals Inc.
2019-07-10	8-AZAGUANINE 134-58-7	US $1.00 / ASSAYS	1ASSAYS	98%	1kg,2kg,100kg	Career Henan Chemical Co

8-Azaguanine
134-58-7
US $7.00-161.00 / g
0.97
Shanghai UCHEM Inc.

8-Azaguanine
134-58-7
US $30.00-55.00 / mg
99.89%
TargetMol Chemicals Inc.

8-AZAGUANINE
134-58-7
US $1.00 / ASSAYS
98%
Career Henan Chemical Co

8-AZAGUANINE Spectrum

8-AZAGUANINE(134-58-7)MS 8-AZAGUANINE(134-58-7)IR1 8-AZAGUANINE(134-58-7)IR2

134-58-7(8-AZAGUANINE)Related Search:

2-Aminopyrimidine 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine Paliperidone Linagliptin Anidulafungin

Bexarotene VILAZODONE SB216763 Nexturastat A Clindamycin

5-[2,4-Dihydroxy-6-(4-nitrophenoxy)phenyl]-N-(1-methyl-4-piperidinyl)-3-isoxazolecarboxamide API-2 Bardoxolone Methyl 8-AZAGUANINE 8-AZAHYPOXANTHINE

Guanine 1H-[1,2,3]TRIAZOL-4-YLMETHYLAMINE HCL 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE

1of4

2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo 5-aMino-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyriMidin-7-one 5-AMino-1H-[1,2,3]triazolo[4,5-d]pyriMidin-7(6H)-one 5-aMino-3H-[1,2,3]triazolo[4,5-d]pyriMidin-7(6H)-one 8-Azaguanine ,99% 8-Azaguanine,2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, 8-AzaG, Guanazolo 7H-1,2,3-Triazolo[4,5-d]pyriMidin-7-one, 5-aMino-3,6-dihydro- 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL 5-amino-2,3-dihydro-[1,2,3]triazolo[4,5-e]pyrimidin-7-one 5-amino-2,3-dihydrotriazolo[4,5-e]pyrimidin-7-one 5-amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol Prestwick_40 8-AzaG {7H-1,2,3- 5-Amino-1H-triazolo[d]pyrimidin-7-ol 5-Amino-1H-v-triazolo(d)pyrimidin-7-ol 5-Amino-7-hydroxy-1H-triazolo[d]pyrimidine 5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine 5-d)pyrimidin-7-ol,5-amino-v-triazolo( 5-d)pyrimidin-7-one,5-amino-1,6-dihydro-7h-v-triazolo( 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-1,4-dihydro- 7H-v-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-1,6-dihydro- 8 AG 8ag Azan AZG B-28 Guanazol NSC-749 Pathocidin Pathocidine SF-337 SK 1150 sk1150 Triazoloanalogofguanine Triazologuanine v-Triazolo(4,5-d)pyrimidin-7-ol, 5-amino- 5-amino-1H-triazolo[4,5-d]pyrimidin-7-ol 8-AZAGUANINE (50X) HYBRI-MAXGAMMA-IRRADI ATED 8-AZAGUANINE 97% 5-AMINO-1,6-DIHYDRO-7H-1,2,3-TRIAZOLO[4,5-D]PYRIMIDIN-7-ONE 5-AMINO-V-TRIAZOLO(4,5-D)-PYRIMIDIN-7-OL 8-AZAQUANINE AZAGUANINE, 8-(RG) GUANAZOLO AZAGUANINE(8-) 8-AZAGUANINE 5-AMINO-3,6-DIHYDRO-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-ONE 5-AMINO-3,6-DIHYDRO-7H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-ONE 5-AMINO-1H-VIC-TRIAZOLO[4,5-D]PYRIMIDINE-7-OL 2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-1,4-dihydro-7H-1 3-triazolo(4,5-d)pyrimidin-7-one,5-amino-1,4-dihydro-7h-2 5-Amino-1,4-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one 5-Amino-1,6-dihydro-7H-v-triazolo(4,5-d)pyrimidin-7-one 2-AMINO-6-HYDROXY-8-AZAPURINE 2-AMINO-6-OXY-8-AZAPURINE 8-Azaguanine, >98% 8-AZAGUANINE USP/EP/BP